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Planned Analysis: Analysis of recurrent fusions #10
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@kgaonkar6 and I would like to work on this analysis. We have already created a workflow for annotating and identifying high-confidence fusions from the two fusion algorithms. |
@kgaonkar6 - for this recurrent analysis, we should pay special attention to samples in which we have diagnosis/relapse pairs (#155) or patient/cell line matched data and should separate/plot differently. For example, we can look at cell line results separately (or exclude from this analysis). For patients with more than one RNA sample, I think we should look into how similar/different they are/if this differs by phase of therapy and think about how to describe this data. |
@kgaonkar6 - in writing up some comments for @cansavvy for #18, I realize we could use the recurrent fusion list here. Can you possibly create a quick PR to create a table of recurrently-fused genes and recurrent fusions by broad cancer type? I think @cansavvy can perhaps start with that for survival analysis. |
Closing all planned analysis tickets in favor of opening new proposed analysis/updated analysis tickets as needed. |
This should probably be partitioned by cancer type and/or molecular subtype. This could be a stacked bar chart (one bar per fusion) for instance with colors representing different cancer types.
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