diff --git a/.changeset/brave-nails-draw.md b/.changeset/brave-nails-draw.md
new file mode 100644
index 00000000..0cf563c4
--- /dev/null
+++ b/.changeset/brave-nails-draw.md
@@ -0,0 +1,5 @@
+---
+'@wyw-in-js/transform': patch
+---
+
+Fix support of :global() selector in nested rules (fixes #42)
diff --git a/packages/transform/src/transform/generators/__tests__/createStylisProcessor.test.ts b/packages/transform/src/transform/generators/__tests__/createStylisProcessor.test.ts
index 3daae2d7..b5b47eef 100644
--- a/packages/transform/src/transform/generators/__tests__/createStylisProcessor.test.ts
+++ b/packages/transform/src/transform/generators/__tests__/createStylisProcessor.test.ts
@@ -98,6 +98,18 @@ describe('stylisGlobalPlugin', () => {
       ).toMatchInlineSnapshot(`".global .component {color:red;}"`);
     });
 
+    it('multi-level nested selector', () => {
+      expect(
+        compileRule(
+          '.component :global() { .global { .nested { color: red } } }'
+        )
+      ).toMatchInlineSnapshot(`".global .nested {color:red;}"`);
+
+      expect(
+        compileRule(':global() { body { .someClassName { color: red; } } }')
+      ).toMatchInlineSnapshot(`"body .someClassName {color:red;}"`);
+    });
+
     it('multiple selectors', () => {
       const cssRuleA = dedent(`
         .component :global() {
diff --git a/packages/transform/src/transform/generators/createStylisPreprocessor.ts b/packages/transform/src/transform/generators/createStylisPreprocessor.ts
index adcbec93..ebe22c9d 100644
--- a/packages/transform/src/transform/generators/createStylisPreprocessor.ts
+++ b/packages/transform/src/transform/generators/createStylisPreprocessor.ts
@@ -8,7 +8,7 @@ import {
   tokenize,
   RULESET,
 } from 'stylis';
-import type { Middleware } from 'stylis';
+import type { Middleware, Element } from 'stylis';
 
 import type { Options } from '../../types';
 
@@ -34,11 +34,36 @@ export function transformUrl(
   return relative.split(platformPath.sep).join(POSIX_SEP);
 }
 
+interface IGlobalSelectorModifiers {
+  includeBaseSelector: boolean;
+  includeSpaceDelimiter: boolean;
+}
+
+const ORIGINAL_VALUE_KEY = Symbol('originalValue');
+
+const getOriginalElementValue = (
+  element: (Element & { [ORIGINAL_VALUE_KEY]?: string }) | null
+) => {
+  return element ? element[ORIGINAL_VALUE_KEY] ?? element.value : '';
+};
+
 /**
  * Stylis plugin that mimics :global() selector behavior from Stylis v3.
  */
 export const stylisGlobalPlugin: Middleware = (element) => {
-  function getGlobalSelectorModifiers(value: string) {
+  function getGlobalSelectorModifiers(el: Element): IGlobalSelectorModifiers {
+    const { parent } = el;
+
+    const value = getOriginalElementValue(el);
+    const parentValue = getOriginalElementValue(parent);
+
+    if (
+      (parent?.children.length === 0 && parentValue.includes(':global(')) ||
+      (parent && !value.includes(':global('))
+    ) {
+      return getGlobalSelectorModifiers(parent);
+    }
+
     const match = value.match(/(&\f( )?)?:global\(/);
 
     if (match === null) {
@@ -73,26 +98,20 @@ export const stylisGlobalPlugin: Middleware = (element) => {
 
       Object.assign(element, {
         props: element.props.map((cssSelector) => {
+          // The value can be changed by other middlewares, but we need an original one with `&`
+          Object.assign(element, { [ORIGINAL_VALUE_KEY]: element.value });
+
           // Avoids calling tokenize() on every string
           if (!cssSelector.includes(':global(')) {
             return cssSelector;
           }
 
           if (element.children.length === 0) {
-            Object.assign(element, {
-              global: getGlobalSelectorModifiers(element.value),
-            });
             return cssSelector;
           }
 
           const { includeBaseSelector, includeSpaceDelimiter } =
-            (
-              element.parent as unknown as
-                | (Element & {
-                    global: ReturnType<typeof getGlobalSelectorModifiers>;
-                  })
-                | undefined
-            )?.global || getGlobalSelectorModifiers(element.value);
+            getGlobalSelectorModifiers(element);
 
           const tokens = tokenize(cssSelector);
           let selector = '';