diff --git a/Cargo.lock b/Cargo.lock
index f0bd37e..f6feb43 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -2,15 +2,6 @@
 # It is not intended for manual editing.
 version = 3
 
-[[package]]
-name = "addr2line"
-version = "0.20.0"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f4fa78e18c64fce05e902adecd7a5eed15a5e0a3439f7b0e169f0252214865e3"
-dependencies = [
- "gimli",
-]
-
 [[package]]
 name = "adler"
 version = "1.0.2"
@@ -19,25 +10,32 @@ checksum = "f26201604c87b1e01bd3d98f8d5d9a8fcbb815e8cedb41ffccbeb4bf593a35fe"
 
 [[package]]
 name = "ahash"
-version = "0.8.3"
+version = "0.8.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2c99f64d1e06488f620f932677e24bc6e2897582980441ae90a671415bd7ec2f"
+checksum = "91429305e9f0a25f6205c5b8e0d2db09e0708a7a6df0f42212bb56c32c8ac97a"
 dependencies = [
  "cfg-if",
  "getrandom",
  "once_cell",
  "version_check",
+ "zerocopy",
 ]
 
 [[package]]
 name = "aho-corasick"
-version = "1.0.2"
+version = "1.1.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "43f6cb1bf222025340178f382c426f13757b2960e89779dfcb319c32542a5a41"
+checksum = "b2969dcb958b36655471fc61f7e416fa76033bdd4bfed0678d8fee1e2d07a1f0"
 dependencies = [
  "memchr",
 ]
 
+[[package]]
+name = "allocator-api2"
+version = "0.2.16"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "0942ffc6dcaadf03badf6e6a2d0228460359d5e34b57ccdc720b7382dfbd5ec5"
+
 [[package]]
 name = "android-tzdata"
 version = "0.1.1"
@@ -79,15 +77,15 @@ dependencies = [
 
 [[package]]
 name = "anstyle"
-version = "1.0.1"
+version = "1.0.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3a30da5c5f2d5e72842e00bcb57657162cdabef0931f40e2deb9b4140440cecd"
+checksum = "7079075b41f533b8c61d2a4d073c4676e1f8b249ff94a393b0595db304e0dd87"
 
 [[package]]
 name = "anstyle-parse"
-version = "0.2.1"
+version = "0.2.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "938874ff5980b03a87c5524b3ae5b59cf99b1d6bc836848df7bc5ada9643c333"
+checksum = "317b9a89c1868f5ea6ff1d9539a69f45dffc21ce321ac1fd1160dfa48c8e2140"
 dependencies = [
  "utf8parse",
 ]
@@ -113,9 +111,9 @@ dependencies = [
 
 [[package]]
 name = "anyhow"
-version = "1.0.71"
+version = "1.0.75"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9c7d0618f0e0b7e8ff11427422b64564d5fb0be1940354bfe2e0529b18a9d9b8"
+checksum = "a4668cab20f66d8d020e1fbc0ebe47217433c1b6c8f2040faf858554e394ace6"
 
 [[package]]
 name = "argminmax"
@@ -142,46 +140,6 @@ dependencies = [
  "serde",
 ]
 
-[[package]]
-name = "arrow2"
-version = "0.17.2"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "15ae0428d69ab31d7b2adad22a752d6f11fef2e901d2262d0cad4f5cb08b7093"
-dependencies = [
- "ahash",
- "arrow-format",
- "bytemuck",
- "chrono",
- "dyn-clone",
- "either",
- "ethnum",
- "foreign_vec",
- "futures",
- "getrandom",
- "hash_hasher",
- "lexical-core",
- "lz4",
- "multiversion",
- "num-traits",
- "regex",
- "regex-syntax 0.6.29",
- "rustc_version",
- "simdutf8",
- "strength_reduce",
- "zstd",
-]
-
-[[package]]
-name = "async-trait"
-version = "0.1.71"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a564d521dd56509c4c47480d00b80ee55f7e385ae48db5744c67ad50c92d2ebf"
-dependencies = [
- "proc-macro2",
- "quote",
- "syn 2.0.32",
-]
-
 [[package]]
 name = "atoi"
 version = "2.0.0"
@@ -197,35 +155,11 @@ version = "1.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "d468802bab17cbc0cc575e9b053f41e72aa36bfa6b7f55e3529ffa43161b97fa"
 
-[[package]]
-name = "backtrace"
-version = "0.3.68"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4319208da049c43661739c5fade2ba182f09d1dc2299b32298d3a31692b17e12"
-dependencies = [
- "addr2line",
- "cc",
- "cfg-if",
- "libc",
- "miniz_oxide",
- "object",
- "rustc-demangle",
-]
-
 [[package]]
 name = "base64"
-version = "0.21.2"
+version = "0.21.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "604178f6c5c21f02dc555784810edfb88d34ac2c73b2eae109655649ee73ce3d"
-
-[[package]]
-name = "bedrs"
-version = "0.0.26"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2e88965de14b05118d0b695991fa0e9867717be1b04e119790cbfb6c4ac1c163"
-dependencies = [
- "anyhow",
-]
+checksum = "35636a1494ede3b646cc98f74f8e62c773a38a659ebc777a2cf26b9b74171df9"
 
 [[package]]
 name = "bit-vec"
@@ -278,47 +212,47 @@ dependencies = [
 
 [[package]]
 name = "bumpalo"
-version = "3.13.0"
+version = "3.14.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a3e2c3daef883ecc1b5d58c15adae93470a91d425f3532ba1695849656af3fc1"
+checksum = "7f30e7476521f6f8af1a1c4c0b8cc94f0bee37d91763d0ca2665f299b6cd8aec"
 
 [[package]]
 name = "bytecount"
-version = "0.6.4"
+version = "0.6.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ad152d03a2c813c80bb94fedbf3a3f02b28f793e39e7c214c8a0bcc196343de7"
+checksum = "e1e5f035d16fc623ae5f74981db80a439803888314e3a555fd6f04acd51a3205"
 
 [[package]]
 name = "bytemuck"
-version = "1.13.1"
+version = "1.14.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "17febce684fd15d89027105661fec94afb475cb995fbc59d2865198446ba2eea"
+checksum = "374d28ec25809ee0e23827c2ab573d729e293f281dfe393500e7ad618baa61c6"
 dependencies = [
  "bytemuck_derive",
 ]
 
 [[package]]
 name = "bytemuck_derive"
-version = "1.4.1"
+version = "1.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fdde5c9cd29ebd706ce1b35600920a33550e402fc998a2e53ad3b42c3c47a192"
+checksum = "965ab7eb5f8f97d2a083c799f3a1b994fc397b2fe2da5d1da1626ce15a39f2b1"
 dependencies = [
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
 name = "byteorder"
-version = "1.4.3"
+version = "1.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "14c189c53d098945499cdfa7ecc63567cf3886b3332b312a5b4585d8d3a6a610"
+checksum = "1fd0f2584146f6f2ef48085050886acf353beff7305ebd1ae69500e27c67f64b"
 
 [[package]]
 name = "bytes"
-version = "1.4.0"
+version = "1.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "89b2fd2a0dcf38d7971e2194b6b6eebab45ae01067456a7fd93d5547a61b70be"
+checksum = "a2bd12c1caf447e69cd4528f47f94d203fd2582878ecb9e9465484c4148a8223"
 
 [[package]]
 name = "bzip2"
@@ -373,9 +307,9 @@ dependencies = [
 
 [[package]]
 name = "clap"
-version = "4.4.6"
+version = "4.4.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d04704f56c2cde07f43e8e2c154b43f216dc5c92fc98ada720177362f953b956"
+checksum = "ac495e00dcec98c83465d5ad66c5c4fabd652fd6686e7c6269b117e729a6f17b"
 dependencies = [
  "clap_builder",
  "clap_derive",
@@ -383,9 +317,9 @@ dependencies = [
 
 [[package]]
 name = "clap_builder"
-version = "4.4.6"
+version = "4.4.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0e231faeaca65ebd1ea3c737966bf858971cd38c3849107aa3ea7de90a804e45"
+checksum = "c77ed9a32a62e6ca27175d00d29d05ca32e396ea1eb5fb01d8256b669cec7663"
 dependencies = [
  "anstream",
  "anstyle",
@@ -396,21 +330,21 @@ dependencies = [
 
 [[package]]
 name = "clap_derive"
-version = "4.4.2"
+version = "4.4.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0862016ff20d69b84ef8247369fabf5c008a7417002411897d40ee1f4532b873"
+checksum = "cf9804afaaf59a91e75b022a30fb7229a7901f60c755489cc61c9b423b836442"
 dependencies = [
  "heck",
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
 name = "clap_lex"
-version = "0.5.0"
+version = "0.6.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2da6da31387c7e4ef160ffab6d5e7f00c42626fe39aea70a7b0f1773f7dd6c1b"
+checksum = "702fc72eb24e5a1e48ce58027a675bc24edd52096d5397d4aea7c6dd9eca0bd1"
 
 [[package]]
 name = "cmd_lib"
@@ -447,9 +381,9 @@ checksum = "acbf1af155f9b9ef647e42cdc158db4b64a1b61f743629225fde6f3e0be2a7c7"
 
 [[package]]
 name = "comfy-table"
-version = "6.2.0"
+version = "7.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7e959d788268e3bf9d35ace83e81b124190378e4c91c9067524675e33394b8ba"
+checksum = "7c64043d6c7b7a4c58e39e7efccfdea7b93d885a795d0c054a69dbbf4dd52686"
 dependencies = [
  "crossterm",
  "strum",
@@ -465,9 +399,9 @@ checksum = "e496a50fda8aacccc86d7529e2c1e0892dbd0f898a6b5645b5561b89c3210efa"
 
 [[package]]
 name = "cpufeatures"
-version = "0.2.9"
+version = "0.2.11"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a17b76ff3a4162b0b27f354a0c87015ddad39d35f9c0c36607a3bdd175dde1f1"
+checksum = "ce420fe07aecd3e67c5f910618fe65e94158f6dcc0adf44e00d69ce2bdfe0fd0"
 dependencies = [
  "libc",
 ]
@@ -515,6 +449,16 @@ dependencies = [
  "scopeguard",
 ]
 
+[[package]]
+name = "crossbeam-queue"
+version = "0.3.8"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "d1cfb3ea8a53f37c40dea2c7bedcbd88bdfae54f5e2175d6ecaff1c988353add"
+dependencies = [
+ "cfg-if",
+ "crossbeam-utils",
+]
+
 [[package]]
 name = "crossbeam-utils"
 version = "0.8.16"
@@ -526,17 +470,14 @@ dependencies = [
 
 [[package]]
 name = "crossterm"
-version = "0.26.1"
+version = "0.27.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a84cda67535339806297f1b331d6dd6320470d2a0fe65381e79ee9e156dd3d13"
+checksum = "f476fe445d41c9e991fd07515a6f463074b782242ccf4a5b7b1d1012e70824df"
 dependencies = [
- "bitflags 1.3.2",
+ "bitflags 2.4.1",
  "crossterm_winapi",
  "libc",
- "mio",
- "parking_lot 0.12.1",
- "signal-hook",
- "signal-hook-mio",
+ "parking_lot",
  "winapi",
 ]
 
@@ -613,9 +554,9 @@ dependencies = [
 
 [[package]]
 name = "dyn-clone"
-version = "1.0.11"
+version = "1.0.14"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "68b0cf012f1230e43cd00ebb729c6bb58707ecfa8ad08b52ef3a4ccd2697fc30"
+checksum = "23d2f3407d9a573d666de4b5bdf10569d73ca9478087346697dcbae6244bfbcd"
 
 [[package]]
 name = "either"
@@ -632,7 +573,7 @@ dependencies = [
  "once_cell",
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -650,9 +591,9 @@ dependencies = [
 
 [[package]]
 name = "equivalent"
-version = "1.0.0"
+version = "1.0.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "88bffebc5d80432c9b140ee17875ff173a8ab62faad5b257da912bd2f6c1c0a1"
+checksum = "5443807d6dff69373d433ab9ef5378ad8df50ca6298caf15de6e52e24aaf54d5"
 
 [[package]]
 name = "errno"
@@ -666,9 +607,9 @@ dependencies = [
 
 [[package]]
 name = "ethnum"
-version = "1.3.2"
+version = "1.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0198b9d0078e0f30dedc7acbb21c974e838fc8fae3ee170128658a98cb2c1c04"
+checksum = "b90ca2580b73ab6a1f724b76ca11ab632df820fd6040c336200d2c1df7b3c82c"
 
 [[package]]
 name = "faccess"
@@ -689,18 +630,15 @@ checksum = "95765f67b4b18863968b4a1bd5bb576f732b29a4a28c7cd84c09fa3e2875f33c"
 
 [[package]]
 name = "fastrand"
-version = "1.9.0"
+version = "2.0.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e51093e27b0797c359783294ca4f0a911c270184cb10f85783b118614a1501be"
-dependencies = [
- "instant",
-]
+checksum = "25cbce373ec4653f1a01a31e8a5e5ec0c622dc27ff9c4e6606eefef5cbbed4a5"
 
 [[package]]
 name = "flate2"
-version = "1.0.26"
+version = "1.0.28"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "3b9429470923de8e8cbd4d2dc513535400b4b3fef0319fb5c4e1f520a7bef743"
+checksum = "46303f565772937ffe1d394a4fac6f411c6013172fadde9dcdb1e147a086940e"
 dependencies = [
  "crc32fast",
  "libz-sys",
@@ -725,95 +663,6 @@ version = "2.0.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "e6d5a32815ae3f33302d95fdcb2ce17862f8c65363dcfd29360480ba1001fc9c"
 
-[[package]]
-name = "futures"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "23342abe12aba583913b2e62f22225ff9c950774065e4bfb61a19cd9770fec40"
-dependencies = [
- "futures-channel",
- "futures-core",
- "futures-executor",
- "futures-io",
- "futures-sink",
- "futures-task",
- "futures-util",
-]
-
-[[package]]
-name = "futures-channel"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "955518d47e09b25bbebc7a18df10b81f0c766eaf4c4f1cccef2fca5f2a4fb5f2"
-dependencies = [
- "futures-core",
- "futures-sink",
-]
-
-[[package]]
-name = "futures-core"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4bca583b7e26f571124fe5b7561d49cb2868d79116cfa0eefce955557c6fee8c"
-
-[[package]]
-name = "futures-executor"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ccecee823288125bd88b4d7f565c9e58e41858e47ab72e8ea2d64e93624386e0"
-dependencies = [
- "futures-core",
- "futures-task",
- "futures-util",
-]
-
-[[package]]
-name = "futures-io"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4fff74096e71ed47f8e023204cfd0aa1289cd54ae5430a9523be060cdb849964"
-
-[[package]]
-name = "futures-macro"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "89ca545a94061b6365f2c7355b4b32bd20df3ff95f02da9329b34ccc3bd6ee72"
-dependencies = [
- "proc-macro2",
- "quote",
- "syn 2.0.32",
-]
-
-[[package]]
-name = "futures-sink"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f43be4fe21a13b9781a69afa4985b0f6ee0e1afab2c6f454a8cf30e2b2237b6e"
-
-[[package]]
-name = "futures-task"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "76d3d132be6c0e6aa1534069c705a74a5997a356c0dc2f86a47765e5617c5b65"
-
-[[package]]
-name = "futures-util"
-version = "0.3.28"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "26b01e40b772d54cf6c6d721c1d1abd0647a0106a12ecaa1c186273392a69533"
-dependencies = [
- "futures-channel",
- "futures-core",
- "futures-io",
- "futures-macro",
- "futures-sink",
- "futures-task",
- "memchr",
- "pin-project-lite",
- "pin-utils",
- "slab",
-]
-
 [[package]]
 name = "fxhash"
 version = "0.2.1"
@@ -846,12 +695,6 @@ dependencies = [
  "wasm-bindgen",
 ]
 
-[[package]]
-name = "gimli"
-version = "0.27.3"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b6c80984affa11d98d1b88b66ac8853f143217b399d3c74116778ff8fdb4ed2e"
-
 [[package]]
 name = "glob"
 version = "0.3.1"
@@ -860,14 +703,15 @@ checksum = "d2fabcfbdc87f4758337ca535fb41a6d701b65693ce38287d856d1674551ec9b"
 
 [[package]]
 name = "grangers"
-version = "0.2.1"
-source = "git+https://github.com/COMBINE-lab/grangers.git?branch=dev#1d780e1911f1a456b4f9d4117628ce16cb05f8a9"
+version = "0.4.0"
+source = "git+https://github.com/COMBINE-lab/grangers.git?branch=dev#eb66072cc70ef95dfd53d48943e63c5e0fa446ba"
 dependencies = [
  "anyhow",
- "bedrs",
  "clap",
  "flate2",
+ "lazy_static",
  "noodles",
+ "nutype",
  "peak_alloc",
  "polars",
  "rust-lapper",
@@ -875,12 +719,6 @@ dependencies = [
  "tracing-subscriber",
 ]
 
-[[package]]
-name = "hash_hasher"
-version = "2.0.3"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "74721d007512d0cb3338cd20f0654ac913920061a4c4d0d8708edb3f2a698c0c"
-
 [[package]]
 name = "hashbrown"
 version = "0.12.3"
@@ -894,14 +732,18 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "43a3c133739dddd0d2990f9a4bdf8eb4b21ef50e4851ca85ab661199821d510e"
 dependencies = [
  "ahash",
- "rayon",
 ]
 
 [[package]]
 name = "hashbrown"
-version = "0.14.0"
+version = "0.14.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2c6201b9ff9fd90a5a3bac2e56a830d0caa509576f0e503818ee82c181b3437a"
+checksum = "f93e7192158dbcda357bdec5fb5788eebf8bbac027f3f33e719d29135ae84156"
+dependencies = [
+ "ahash",
+ "allocator-api2",
+ "rayon",
+]
 
 [[package]]
 name = "heck"
@@ -911,9 +753,9 @@ checksum = "95505c38b4572b2d910cecb0281560f54b440a19336cbbcb27bf6ce6adc6f5a8"
 
 [[package]]
 name = "hermit-abi"
-version = "0.3.2"
+version = "0.3.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "443144c8cdadd93ebf52ddb4056d257f5b52c04d3c804e657d19eb73fc33668b"
+checksum = "d77f7ec81a6d05a3abb01ab6eb7590f6083d08449fe5a1c8b1e620283546ccb7"
 
 [[package]]
 name = "home"
@@ -932,16 +774,16 @@ checksum = "9a3a5bfb195931eeb336b2a7b4d761daec841b97f947d34394601737a7bba5e4"
 
 [[package]]
 name = "iana-time-zone"
-version = "0.1.57"
+version = "0.1.58"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2fad5b825842d2b38bd206f3e81d6957625fd7f0a361e345c30e01a0ae2dd613"
+checksum = "8326b86b6cff230b97d0d312a6c40a60726df3332e721f72a1b035f451663b20"
 dependencies = [
  "android_system_properties",
  "core-foundation-sys",
  "iana-time-zone-haiku",
  "js-sys",
  "wasm-bindgen",
- "windows",
+ "windows-core",
 ]
 
 [[package]]
@@ -965,32 +807,12 @@ dependencies = [
 
 [[package]]
 name = "indexmap"
-version = "2.0.0"
+version = "2.0.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d5477fe2230a79769d8dc68e0eabf5437907c0457a5614a9e8dddb67f65eb65d"
+checksum = "8adf3ddd720272c6ea8bf59463c04e0f93d0bbf7c5439b691bca2987e0270897"
 dependencies = [
  "equivalent",
- "hashbrown 0.14.0",
-]
-
-[[package]]
-name = "instant"
-version = "0.1.12"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7a5bbe824c507c5da5956355e86a746d82e0e1464f65d862cc5e71da70e94b2c"
-dependencies = [
- "cfg-if",
-]
-
-[[package]]
-name = "io-lifetimes"
-version = "1.0.11"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "eae7b9aee968036d54dce06cebaefd919e4472e753296daccd6d344e3e2df0c2"
-dependencies = [
- "hermit-abi",
- "libc",
- "windows-sys",
+ "hashbrown 0.14.2",
 ]
 
 [[package]]
@@ -1000,7 +822,7 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "cb0889898416213fab133e1d33a0e5858a48177452750691bde3666d0fdbaf8b"
 dependencies = [
  "hermit-abi",
- "rustix 0.38.19",
+ "rustix",
  "windows-sys",
 ]
 
@@ -1015,15 +837,15 @@ dependencies = [
 
 [[package]]
 name = "itoa"
-version = "1.0.8"
+version = "1.0.9"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "62b02a5381cc465bd3041d84623d0fa3b66738b52b8e2fc3bab8ad63ab032f4a"
+checksum = "af150ab688ff2122fcef229be89cb50dd66af9e01a4ff320cc137eecc9bacc38"
 
 [[package]]
 name = "jobserver"
-version = "0.1.26"
+version = "0.1.27"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "936cfd212a0155903bcbc060e316fb6cc7cbf2e1907329391ebadc1fe0ce77c2"
+checksum = "8c37f63953c4c63420ed5fd3d6d398c719489b9f872b9fa683262f8edd363c7d"
 dependencies = [
  "libc",
 ]
@@ -1070,7 +892,7 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "c11fb98940a7f8b419619e98ccbf2e094671a5fdd0e277f05acd373071186d57"
 dependencies = [
  "jrsonnet-gcmodule-derive",
- "parking_lot 0.12.1",
+ "parking_lot",
 ]
 
 [[package]]
@@ -1256,15 +1078,15 @@ checksum = "a08173bc88b7955d1b3145aa561539096c421ac8debde8cbc3612ec635fee29b"
 
 [[package]]
 name = "libm"
-version = "0.2.7"
+version = "0.2.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f7012b1bbb0719e1097c47611d3898568c546d597c2e74d66f6087edd5233ff4"
+checksum = "4ec2a862134d2a7d32d7983ddcdd1c4923530833c9f2ea1a44fc5fa473989058"
 
 [[package]]
 name = "libz-sys"
-version = "1.1.9"
+version = "1.1.12"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "56ee889ecc9568871456d42f603d6a0ce59ff328d291063a45cbdf0036baf6db"
+checksum = "d97137b25e321a73eef1418d1d5d2eda4d77e12813f8e6dead84bc52c5870a7b"
 dependencies = [
  "cc",
  "pkg-config",
@@ -1277,12 +1099,6 @@ version = "0.5.6"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "0717cef1bc8b636c6e1c1bbdefc09e6322da8a9321966e8928ef80d20f7f770f"
 
-[[package]]
-name = "linux-raw-sys"
-version = "0.3.8"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ef53942eb7bf7ff43a617b3e2c1c4a5ecf5944a7c1bc12d7ee39bbb15e5c1519"
-
 [[package]]
 name = "linux-raw-sys"
 version = "0.4.10"
@@ -1291,9 +1107,9 @@ checksum = "da2479e8c062e40bf0066ffa0bc823de0a9368974af99c9f6df941d2c231e03f"
 
 [[package]]
 name = "lock_api"
-version = "0.4.10"
+version = "0.4.11"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "c1cc9717a20b1bb222f333e6a92fd32f7d8a18ddc5a3191a11af45dcbf4dcd16"
+checksum = "3c168f8615b12bc01f9c17e2eb0cc07dcae1940121185446edc3744920e8ef45"
 dependencies = [
  "autocfg",
  "scopeguard",
@@ -1301,9 +1117,9 @@ dependencies = [
 
 [[package]]
 name = "log"
-version = "0.4.19"
+version = "0.4.20"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b06a4cde4c0f271a446782e3eff8de789548ce57dbc8eca9292c27f4a42004b4"
+checksum = "b5e6163cb8c49088c2c36f57875e58ccd8c87c7427f7fbd50ea6710b2f3f2e8f"
 
 [[package]]
 name = "lz4"
@@ -1359,15 +1175,15 @@ checksum = "490cc448043f947bae3cbee9c203358d62dbee0db12107a74be5c30ccfd09771"
 
 [[package]]
 name = "memchr"
-version = "2.5.0"
+version = "2.6.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2dffe52ecf27772e601905b7522cb4ef790d2cc203488bbd0e2fe85fcb74566d"
+checksum = "f665ee40bc4a3c5590afb1e9677db74a508659dfd71e126420da8274909a0167"
 
 [[package]]
 name = "memmap2"
-version = "0.5.10"
+version = "0.7.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "83faa42c0a078c393f6b29d5db232d8be22776a891f8f56e5284faee4a20b327"
+checksum = "f49388d20533534cd19360ad3d6a7dadc885944aa802ba3995040c5ec11288c6"
 dependencies = [
  "libc",
 ]
@@ -1399,23 +1215,11 @@ dependencies = [
  "adler",
 ]
 
-[[package]]
-name = "mio"
-version = "0.8.8"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "927a765cd3fc26206e66b296465fa9d3e5ab003e651c1b3c060e7956d96b19d2"
-dependencies = [
- "libc",
- "log",
- "wasi",
- "windows-sys",
-]
-
 [[package]]
 name = "multiversion"
-version = "0.7.2"
+version = "0.7.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8cda45dade5144c2c929bf2ed6c24bebbba784e9198df049ec87d722b9462bd1"
+checksum = "b2c7b9d7fe61760ce5ea19532ead98541f6b4c495d87247aff9826445cf6872a"
 dependencies = [
  "multiversion-macros",
  "target-features",
@@ -1423,9 +1227,9 @@ dependencies = [
 
 [[package]]
 name = "multiversion-macros"
-version = "0.7.2"
+version = "0.7.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "04bffdccbd4798b61dce08c97ce8c66a68976f95541aaf284a6e90c1d1c306e1"
+checksum = "26a83d8500ed06d68877e9de1dde76c1dbb83885dcdbda4ef44ccbc3fbda2ac8"
 dependencies = [
  "proc-macro2",
  "quote",
@@ -1449,23 +1253,22 @@ dependencies = [
 
 [[package]]
 name = "nix"
-version = "0.26.2"
+version = "0.26.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "bfdda3d196821d6af13126e40375cdf7da646a96114af134d5f417a9a1dc8e1a"
+checksum = "598beaf3cc6fdd9a5dfb1630c2800c7acd31df7aaf0f565796fba2b53ca1af1b"
 dependencies = [
  "bitflags 1.3.2",
  "cfg-if",
  "libc",
  "memoffset 0.7.1",
  "pin-utils",
- "static_assertions",
 ]
 
 [[package]]
 name = "noodles"
-version = "0.44.0"
+version = "0.56.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "57213e65425cd2be8923d39ad3cd13c0847949dc9ed3e1bef73f2733d84c0570"
+checksum = "9ba860dd272b95bc6758e9cf1ec9d13d159c928726b020432a88bd897ca75bbb"
 dependencies = [
  "noodles-core",
  "noodles-fasta",
@@ -1475,9 +1278,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-bgzf"
-version = "0.22.0"
+version = "0.25.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2985a96e0306878a47e223f1bc8b5c988de6ef1516797796e05349dac0a727b2"
+checksum = "7d578e5a173cbfac77295db4188c959966ce24a3364e009d363170d1ed44066a"
 dependencies = [
  "byteorder",
  "bytes",
@@ -1493,22 +1296,22 @@ checksum = "94fbe3192fe33acacabaedd387657f39b0fc606f1996d546db0dfe14703b843a"
 
 [[package]]
 name = "noodles-csi"
-version = "0.22.0"
+version = "0.26.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "55329e145d9b5ba58299e3f9e36512d143e19379f13c3480db7346bcfaadc679"
+checksum = "e0531175d5473e6057c1724c1242b19bfc42dba644fe275b4df89c5b8d31a782"
 dependencies = [
  "bit-vec",
  "byteorder",
- "indexmap 2.0.0",
+ "indexmap 2.0.2",
  "noodles-bgzf",
  "noodles-core",
 ]
 
 [[package]]
 name = "noodles-fasta"
-version = "0.25.0"
+version = "0.30.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e096096e1c04ab76fe034ea499c692d8a4401a321155b542cd8ea3b1f7d08d12"
+checksum = "310dcfb61e8e2cafb65d9da4b329a98a390f2b570c17599a7f4639328cfb3e2c"
 dependencies = [
  "bytes",
  "memchr",
@@ -1518,10 +1321,11 @@ dependencies = [
 
 [[package]]
 name = "noodles-gff"
-version = "0.16.0"
+version = "0.23.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "112d886335b986e5716de8c02291565813fd3be65053e3f5774b95399434af4f"
+checksum = "2a70052d45f0bf58198617f282a6564c2c22602aa9bfff293a30b90060148ce6"
 dependencies = [
+ "indexmap 2.0.2",
  "noodles-bgzf",
  "noodles-core",
  "noodles-csi",
@@ -1530,9 +1334,9 @@ dependencies = [
 
 [[package]]
 name = "noodles-gtf"
-version = "0.14.0"
+version = "0.19.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "096367bb382b244da2dc087a9628daecae299a5641f6572f28627f2001187465"
+checksum = "fc089e0d2a80c447213126e85d52b4408ed7a737f64e4a01521336962a6f67aa"
 dependencies = [
  "noodles-bgzf",
  "noodles-core",
@@ -1569,31 +1373,32 @@ dependencies = [
 
 [[package]]
 name = "num-traits"
-version = "0.2.15"
+version = "0.2.17"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "578ede34cf02f8924ab9447f50c28075b4d3e5b269972345e7e0372b38c6cdcd"
+checksum = "39e3200413f237f41ab11ad6d161bc7239c84dcb631773ccd7de3dfe4b5c267c"
 dependencies = [
  "autocfg",
  "libm",
 ]
 
 [[package]]
-name = "num_cpus"
-version = "1.16.0"
+name = "nutype"
+version = "0.3.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4161fcb6d602d4d2081af7c3a45852d875a03dd337a6bfdd6e06407b61342a43"
+checksum = "0ae1c26994c543093dea62dc235aba699a8ea1ba5bcab09449a757449a643a91"
 dependencies = [
- "hermit-abi",
- "libc",
+ "nutype_macros",
 ]
 
 [[package]]
-name = "object"
-version = "0.31.1"
+name = "nutype_macros"
+version = "0.3.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8bda667d9f2b5051b8833f59f3bf748b28ef54f850f4fcb389a252aa383866d1"
+checksum = "1f23758ee2f73e58d93bad0e422ed9cbb9a9609797c2ee3b27f8c1537b38a2ca"
 dependencies = [
- "memchr",
+ "proc-macro2",
+ "quote",
+ "syn 1.0.109",
 ]
 
 [[package]]
@@ -1640,17 +1445,6 @@ dependencies = [
  "unicode-width",
 ]
 
-[[package]]
-name = "parking_lot"
-version = "0.11.2"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7d17b78036a60663b797adeaee46f5c9dfebb86948d1255007a1d6be0271ff99"
-dependencies = [
- "instant",
- "lock_api",
- "parking_lot_core 0.8.6",
-]
-
 [[package]]
 name = "parking_lot"
 version = "0.12.1"
@@ -1658,32 +1452,18 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "3742b2c103b9f06bc9fff0a37ff4912935851bee6d36f3c02bcc755bcfec228f"
 dependencies = [
  "lock_api",
- "parking_lot_core 0.9.8",
+ "parking_lot_core",
 ]
 
 [[package]]
 name = "parking_lot_core"
-version = "0.8.6"
+version = "0.9.9"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "60a2cfe6f0ad2bfc16aefa463b497d5c7a5ecd44a23efa72aa342d90177356dc"
+checksum = "4c42a9226546d68acdd9c0a280d17ce19bfe27a46bf68784e4066115788d008e"
 dependencies = [
  "cfg-if",
- "instant",
  "libc",
- "redox_syscall 0.2.16",
- "smallvec",
- "winapi",
-]
-
-[[package]]
-name = "parking_lot_core"
-version = "0.9.8"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "93f00c865fe7cabf650081affecd3871070f26767e7b2070a3ffae14c654b447"
-dependencies = [
- "cfg-if",
- "libc",
- "redox_syscall 0.3.5",
+ "redox_syscall",
  "smallvec",
  "windows-targets",
 ]
@@ -1702,9 +1482,9 @@ checksum = "84d3978b0aa7d46c34452384c28264ac859c652b67635f6acfd598e1b6608de5"
 
 [[package]]
 name = "peg"
-version = "0.8.1"
+version = "0.8.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a07f2cafdc3babeebc087e499118343442b742cc7c31b4d054682cc598508554"
+checksum = "400bcab7d219c38abf8bd7cc2054eb9bbbd4312d66f6a5557d572a203f646f61"
 dependencies = [
  "peg-macros",
  "peg-runtime",
@@ -1712,9 +1492,9 @@ dependencies = [
 
 [[package]]
 name = "peg-macros"
-version = "0.8.1"
+version = "0.8.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4a90084dc05cf0428428e3d12399f39faad19b0909f64fb9170c9fdd6d9cd49b"
+checksum = "46e61cce859b76d19090f62da50a9fe92bab7c2a5f09e183763559a2ac392c90"
 dependencies = [
  "peg-runtime",
  "proc-macro2",
@@ -1723,9 +1503,9 @@ dependencies = [
 
 [[package]]
 name = "peg-runtime"
-version = "0.8.1"
+version = "0.8.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9fa00462b37ead6d11a82c9d568b26682d78e0477dc02d1966c013af80969739"
+checksum = "36bae92c60fa2398ce4678b98b2c4b5a7c61099961ca1fa305aec04a9ad28922"
 
 [[package]]
 name = "percent-encoding"
@@ -1735,19 +1515,20 @@ checksum = "9b2a4787296e9989611394c33f193f676704af1686e70b8f8033ab5ba9a35a94"
 
 [[package]]
 name = "pest"
-version = "2.7.0"
+version = "2.7.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f73935e4d55e2abf7f130186537b19e7a4abc886a0252380b59248af473a3fc9"
+checksum = "ae9cee2a55a544be8b89dc6848072af97a20f2422603c10865be2a42b580fff5"
 dependencies = [
+ "memchr",
  "thiserror",
  "ucd-trie",
 ]
 
 [[package]]
 name = "pest_derive"
-version = "2.7.0"
+version = "2.7.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "aef623c9bbfa0eedf5a0efba11a5ee83209c326653ca31ff019bec3a95bfff2b"
+checksum = "81d78524685f5ef2a3b3bd1cafbc9fcabb036253d9b1463e726a91cd16e2dfc2"
 dependencies = [
  "pest",
  "pest_generator",
@@ -1755,22 +1536,22 @@ dependencies = [
 
 [[package]]
 name = "pest_generator"
-version = "2.7.0"
+version = "2.7.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b3e8cba4ec22bada7fc55ffe51e2deb6a0e0db2d0b7ab0b103acc80d2510c190"
+checksum = "68bd1206e71118b5356dae5ddc61c8b11e28b09ef6a31acbd15ea48a28e0c227"
 dependencies = [
  "pest",
  "pest_meta",
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
 name = "pest_meta"
-version = "2.7.0"
+version = "2.7.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a01f71cb40bd8bb94232df14b946909e14660e33fc05db3e50ae2a82d7ea0ca0"
+checksum = "7c747191d4ad9e4a4ab9c8798f1e82a39affe7ef9648390b7e5548d18e099de6"
 dependencies = [
  "once_cell",
  "pest",
@@ -1807,7 +1588,7 @@ dependencies = [
  "phf_shared",
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -1821,9 +1602,9 @@ dependencies = [
 
 [[package]]
 name = "pin-project-lite"
-version = "0.2.10"
+version = "0.2.13"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4c40d25201921e5ff0c862a505c6557ea88568a4e3ace775ab55e93f2f4f9d57"
+checksum = "8afb450f006bf6385ca15ef45d71d2288452bc3683ce2e2cacc0d18e4be60b58"
 
 [[package]]
 name = "pin-utils"
@@ -1848,9 +1629,9 @@ dependencies = [
 
 [[package]]
 name = "polars"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "c464be75f4ec8b1a8527a55583f67961e3514f112a99f789476a7ccb9a397d10"
+checksum = "40db657cc67a8dd9fe4b40db5b73027f5f224623545597e1930cbbb9c05b1de5"
 dependencies = [
  "getrandom",
  "polars-core",
@@ -1864,32 +1645,46 @@ dependencies = [
 
 [[package]]
 name = "polars-arrow"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4f187a7fd8fbef04d6a810bfd4c181baf584fc4439ec054e0caad4325bf00f95"
+checksum = "d1e50c63db77f846ac5119477422f0156f0a1826ceaae7d921f9a6d5ea5f7ca3"
 dependencies = [
- "arrow2",
- "hashbrown 0.13.2",
+ "ahash",
+ "arrow-format",
+ "bytemuck",
+ "chrono",
+ "dyn-clone",
+ "either",
+ "ethnum",
+ "foreign_vec",
+ "getrandom",
+ "hashbrown 0.14.2",
+ "lexical-core",
+ "lz4",
  "multiversion",
  "num-traits",
  "polars-error",
- "thiserror",
+ "rustc_version",
+ "simdutf8",
+ "streaming-iterator",
+ "strength_reduce",
+ "zstd",
 ]
 
 [[package]]
 name = "polars-core"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "78b7216aa3336fd2a7b5ebfa66748f3770682b28cd682930d1abf59b53b670e0"
+checksum = "cdfb622b8ca81b4614c64d95e7590d6e0571d7d398b5ad595c1abc4412abe714"
 dependencies = [
  "ahash",
- "arrow2",
- "bitflags 1.3.2",
+ "bitflags 2.4.1",
+ "bytemuck",
  "chrono",
  "comfy-table",
  "either",
- "hashbrown 0.13.2",
- "indexmap 1.9.3",
+ "hashbrown 0.14.2",
+ "indexmap 2.0.2",
  "num-traits",
  "once_cell",
  "polars-arrow",
@@ -1902,41 +1697,40 @@ dependencies = [
  "regex",
  "smartstring",
  "thiserror",
- "wasm-timer",
+ "version_check",
  "xxhash-rust",
 ]
 
 [[package]]
 name = "polars-error"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dfb4f020b2b6d12408cca6b081dbd928fef8bbe9cdbba4c88441e61ade33bc2d"
+checksum = "4b6480520ebde0b20935b600483b865513891e36c04942cebdd19e4f338257b4"
 dependencies = [
- "arrow2",
+ "arrow-format",
  "regex",
+ "simdutf8",
  "thiserror",
 ]
 
 [[package]]
 name = "polars-io"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "270650704e08bef37d227a6904b36c4bdad2d013536ea3c57f40007c19ad2ebc"
+checksum = "666466a3b151047c76d99b4e4e5f5438895ef97848008cf49b06df8e3d2d395a"
 dependencies = [
  "ahash",
- "arrow2",
- "async-trait",
  "bytes",
  "chrono",
  "fast-float",
- "futures",
  "home",
+ "itoa",
  "lexical",
- "lexical-core",
  "memchr",
  "memmap2",
  "num-traits",
  "once_cell",
+ "percent-encoding",
  "polars-arrow",
  "polars-core",
  "polars-error",
@@ -1944,18 +1738,19 @@ dependencies = [
  "polars-utils",
  "rayon",
  "regex",
+ "ryu",
  "simdutf8",
- "tokio",
+ "smartstring",
 ]
 
 [[package]]
 name = "polars-lazy"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "f2a8fe41263496b5212098f19d0cdddc11f75c71957a09d2ce300a8fdb4407e3"
+checksum = "07e1c2da1ca20106f80d9510090344e7311fd1dcfd6e6b65031e10606c0958c7"
 dependencies = [
  "ahash",
- "bitflags 1.3.2",
+ "bitflags 2.4.1",
  "glob",
  "once_cell",
  "polars-arrow",
@@ -1968,32 +1763,43 @@ dependencies = [
  "polars-utils",
  "rayon",
  "smartstring",
+ "version_check",
 ]
 
 [[package]]
 name = "polars-ops"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d63c31565b88f31457abafb224166fdc0824bf2954414f0c5c52b31c09189942"
+checksum = "0fe2d37a6a3ef358499d43aecee80740e62dd44e6cfe7a9c4aa0b8db88de8292"
 dependencies = [
+ "ahash",
  "argminmax",
- "arrow2",
+ "bytemuck",
  "either",
+ "hashbrown 0.14.2",
+ "indexmap 2.0.2",
  "memchr",
+ "num-traits",
  "polars-arrow",
  "polars-core",
+ "polars-error",
  "polars-utils",
+ "rayon",
+ "regex",
  "smartstring",
+ "version_check",
 ]
 
 [[package]]
 name = "polars-pipe"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "51076665e7e45f536a2f080763db040e38eab9fdb1cd927b93428720ba23c46a"
+checksum = "f6aa050d529be01617f54bc60658149da76f97dbea9fdac3c9d60b811f64a2ba"
 dependencies = [
+ "crossbeam-channel",
+ "crossbeam-queue",
  "enum_dispatch",
- "hashbrown 0.13.2",
+ "hashbrown 0.14.2",
  "num-traits",
  "polars-arrow",
  "polars-core",
@@ -2004,17 +1810,19 @@ dependencies = [
  "polars-utils",
  "rayon",
  "smartstring",
+ "version_check",
 ]
 
 [[package]]
 name = "polars-plan"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8a7d0f48bdd7fa9474f718ecb99fc12d97671933707091a249bb0da96b30f291"
+checksum = "c47e5d62d8f612aab61a6331d04c5c95c9ff301106d8b91131c8833b4ef3def6"
 dependencies = [
  "ahash",
- "arrow2",
+ "bytemuck",
  "once_cell",
+ "percent-encoding",
  "polars-arrow",
  "polars-core",
  "polars-io",
@@ -2024,29 +1832,33 @@ dependencies = [
  "rayon",
  "regex",
  "smartstring",
+ "strum_macros",
+ "version_check",
 ]
 
 [[package]]
 name = "polars-row"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b18fa58195b88fdd32c98561cbeff4024b106cdd2a8c975e7d06544324d0e4d1"
+checksum = "f05d6544f7d6065fcaa93bc69aac0532ce09aab4f81ec03c9a78dd901bb0c05b"
 dependencies = [
- "arrow2",
+ "polars-arrow",
  "polars-error",
  "polars-utils",
 ]
 
 [[package]]
 name = "polars-sql"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8485d0c9664e67123b065c8a7c946a0165b0192c05c24cdcde447b1c9e05c7e5"
+checksum = "77f65f9c8bfe7f0b2c08c38c79b92ec4ddaf213fc424d94a6272ed7b2d83987f"
 dependencies = [
  "polars-arrow",
  "polars-core",
+ "polars-error",
  "polars-lazy",
  "polars-plan",
+ "rand",
  "serde",
  "serde_json",
  "sqlparser",
@@ -2054,17 +1866,17 @@ dependencies = [
 
 [[package]]
 name = "polars-time"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "5c0d11ef8a93b2d204a60da7099510c40fe1ac04d95022ae4daa39df31b345e1"
+checksum = "3763af36aeeb85ef083f11c43bc28c5b6222e2aae039c5118d916bc855f2b5b9"
 dependencies = [
- "arrow2",
  "atoi",
  "chrono",
  "now",
  "once_cell",
  "polars-arrow",
  "polars-core",
+ "polars-error",
  "polars-ops",
  "polars-utils",
  "regex",
@@ -2073,16 +1885,20 @@ dependencies = [
 
 [[package]]
 name = "polars-utils"
-version = "0.30.0"
+version = "0.34.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "145a59f928f8317fcf543407ef1b83e827448462e05e2fc6444162fcec84386a"
+checksum = "55d2c038ff67e4eb6019682c3f66d83f744e285de9c28e816109a61bace824cd"
 dependencies = [
  "ahash",
- "hashbrown 0.13.2",
+ "bytemuck",
+ "hashbrown 0.14.2",
+ "num-traits",
  "once_cell",
+ "polars-error",
  "rayon",
  "smartstring",
  "sysinfo",
+ "version_check",
 ]
 
 [[package]]
@@ -2187,9 +2003,9 @@ dependencies = [
 
 [[package]]
 name = "rayon"
-version = "1.7.0"
+version = "1.8.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1d2df5196e37bcc87abebc0053e20787d73847bb33134a69841207dd0a47f03b"
+checksum = "9c27db03db7734835b3f53954b534c91069375ce6ccaa2e065441e07d9b6cdb1"
 dependencies = [
  "either",
  "rayon-core",
@@ -2197,44 +2013,33 @@ dependencies = [
 
 [[package]]
 name = "rayon-core"
-version = "1.11.0"
+version = "1.12.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4b8f95bd6966f5c87776639160a66bd8ab9895d9d4ab01ddba9fc60661aebe8d"
+checksum = "5ce3fb6ad83f861aac485e76e1985cd109d9a3713802152be56c3b1f0e0658ed"
 dependencies = [
- "crossbeam-channel",
  "crossbeam-deque",
  "crossbeam-utils",
- "num_cpus",
-]
-
-[[package]]
-name = "redox_syscall"
-version = "0.2.16"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fb5a58c1855b4b6819d59012155603f0b22ad30cad752600aadfcb695265519a"
-dependencies = [
- "bitflags 1.3.2",
 ]
 
 [[package]]
 name = "redox_syscall"
-version = "0.3.5"
+version = "0.4.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "567664f262709473930a4bf9e51bf2ebf3348f2e748ccc50dea20646858f8f29"
+checksum = "4722d768eff46b75989dd134e5c353f0d6296e5aaa3132e776cbdb56be7731aa"
 dependencies = [
  "bitflags 1.3.2",
 ]
 
 [[package]]
 name = "regex"
-version = "1.9.1"
+version = "1.10.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b2eae68fc220f7cf2532e4494aded17545fce192d59cd996e0fe7887f4ceb575"
+checksum = "380b951a9c5e80ddfd6136919eef32310721aa4aacd4889a8d39124b026ab343"
 dependencies = [
  "aho-corasick",
  "memchr",
- "regex-automata 0.3.2",
- "regex-syntax 0.7.3",
+ "regex-automata 0.4.3",
+ "regex-syntax 0.8.2",
 ]
 
 [[package]]
@@ -2248,13 +2053,13 @@ dependencies = [
 
 [[package]]
 name = "regex-automata"
-version = "0.3.2"
+version = "0.4.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "83d3daa6976cffb758ec878f108ba0e062a45b2d6ca3a2cca965338855476caf"
+checksum = "5f804c7828047e88b2d32e2d7fe5a105da8ee3264f01902f796c8e067dc2483f"
 dependencies = [
  "aho-corasick",
  "memchr",
- "regex-syntax 0.7.3",
+ "regex-syntax 0.8.2",
 ]
 
 [[package]]
@@ -2265,14 +2070,14 @@ checksum = "f162c6dd7b008981e4d40210aca20b4bd0f9b60ca9271061b07f78537722f2e1"
 
 [[package]]
 name = "regex-syntax"
-version = "0.7.3"
+version = "0.8.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "2ab07dc67230e4a4718e70fd5c20055a4334b121f1f9db8fe63ef39ce9b8c846"
+checksum = "c08c74e62047bb2de4ff487b251e4a92e24f48745648451635cec7d591162d9f"
 
 [[package]]
 name = "roers"
-version = "0.2.0"
-source = "git+https://github.com/COMBINE-lab/roers?branch=main#c7d21fccb05d3ed5173a7a34665a4fbbbeb28a23"
+version = "0.3.0"
+source = "git+https://github.com/COMBINE-lab/roers?branch=main#a1cb54e79c2cb2c0af1d2c9ba92e1e3b3b6f63cd"
 dependencies = [
  "anyhow",
  "clap",
@@ -2298,12 +2103,6 @@ dependencies = [
  "num-traits",
 ]
 
-[[package]]
-name = "rustc-demangle"
-version = "0.1.23"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d626bb9dae77e28219937af045c257c28bfd3f69333c512553507f5f9798cb76"
-
 [[package]]
 name = "rustc-hash"
 version = "1.1.0"
@@ -2321,42 +2120,28 @@ dependencies = [
 
 [[package]]
 name = "rustix"
-version = "0.37.23"
+version = "0.38.21"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4d69718bf81c6127a49dc64e44a742e8bb9213c0ff8869a22c308f84c1d4ab06"
-dependencies = [
- "bitflags 1.3.2",
- "errno",
- "io-lifetimes",
- "libc",
- "linux-raw-sys 0.3.8",
- "windows-sys",
-]
-
-[[package]]
-name = "rustix"
-version = "0.38.19"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "745ecfa778e66b2b63c88a61cb36e0eea109e803b0b86bf9879fbc77c70e86ed"
+checksum = "2b426b0506e5d50a7d8dafcf2e81471400deb602392c7dd110815afb4eaf02a3"
 dependencies = [
  "bitflags 2.4.1",
  "errno",
  "libc",
- "linux-raw-sys 0.4.10",
+ "linux-raw-sys",
  "windows-sys",
 ]
 
 [[package]]
 name = "rustversion"
-version = "1.0.13"
+version = "1.0.14"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "dc31bd9b61a32c31f9650d18add92aa83a49ba979c143eefd27fe7177b05bd5f"
+checksum = "7ffc183a10b4478d04cbbbfc96d0873219d962dd5accaff2ffbd4ceb7df837f4"
 
 [[package]]
 name = "ryu"
-version = "1.0.14"
+version = "1.0.15"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fe232bdf6be8c8de797b22184ee71118d63780ea42ac85b61d1baa6d3b782ae9"
+checksum = "1ad4cc8da4ef723ed60bced201181d83791ad433213d8c24efffda1eec85d741"
 
 [[package]]
 name = "safemem"
@@ -2366,9 +2151,9 @@ checksum = "ef703b7cb59335eae2eb93ceb664c0eb7ea6bf567079d843e09420219668e072"
 
 [[package]]
 name = "scopeguard"
-version = "1.1.0"
+version = "1.2.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d29ab0c6d3fc0ee92fe66e2d99f700eab17a8d57d1c1d3b748380fb20baa78cd"
+checksum = "94143f37725109f92c262ed2cf5e59bce7498c01bcc1502d7b9afe439a4e9f49"
 
 [[package]]
 name = "semver"
@@ -2405,22 +2190,22 @@ dependencies = [
 
 [[package]]
 name = "serde"
-version = "1.0.189"
+version = "1.0.190"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "8e422a44e74ad4001bdc8eede9a4570ab52f71190e9c076d14369f38b9200537"
+checksum = "91d3c334ca1ee894a2c6f6ad698fe8c435b76d504b13d436f0685d648d6d96f7"
 dependencies = [
  "serde_derive",
 ]
 
 [[package]]
 name = "serde_derive"
-version = "1.0.189"
+version = "1.0.190"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1e48d1f918009ce3145511378cf68d613e3b3d9137d67272562080d68a2b32d5"
+checksum = "67c5609f394e5c2bd7fc51efda478004ea80ef42fee983d5c67a65e34f32c0e3"
 dependencies = [
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -2459,9 +2244,9 @@ dependencies = [
 
 [[package]]
 name = "sha2"
-version = "0.10.7"
+version = "0.10.8"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "479fb9d862239e610720565ca91403019f2f00410f1864c5aa7479b950a76ed8"
+checksum = "793db75ad2bcafc3ffa7c68b215fee268f537982cd901d132f89c6343f3a3dc8"
 dependencies = [
  "cfg-if",
  "cpufeatures",
@@ -2480,43 +2265,13 @@ dependencies = [
 
 [[package]]
 name = "sharded-slab"
-version = "0.1.4"
+version = "0.1.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "900fba806f70c630b0a382d0d825e17a0f19fcd059a2ade1ff237bcddf446b31"
+checksum = "f40ca3c46823713e0d4209592e8d6e826aa57e928f09752619fc696c499637f6"
 dependencies = [
  "lazy_static",
 ]
 
-[[package]]
-name = "signal-hook"
-version = "0.3.15"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "732768f1176d21d09e076c23a93123d40bba92d50c4058da34d45c8de8e682b9"
-dependencies = [
- "libc",
- "signal-hook-registry",
-]
-
-[[package]]
-name = "signal-hook-mio"
-version = "0.2.3"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "29ad2e15f37ec9a6cc544097b78a1ec90001e9f71b81338ca39f430adaca99af"
-dependencies = [
- "libc",
- "mio",
- "signal-hook",
-]
-
-[[package]]
-name = "signal-hook-registry"
-version = "1.4.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d8229b473baa5980ac72ef434c4415e70c4b5e71b423043adb4ba059f89c99a1"
-dependencies = [
- "libc",
-]
-
 [[package]]
 name = "simdutf8"
 version = "0.1.4"
@@ -2552,24 +2307,15 @@ dependencies = [
 
 [[package]]
 name = "siphasher"
-version = "0.3.10"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7bd3e3206899af3f8b12af284fafc038cc1dc2b41d1b89dd17297221c5d225de"
-
-[[package]]
-name = "slab"
-version = "0.4.8"
+version = "0.3.11"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "6528351c9bc8ab22353f9d776db39a20288e8d6c37ef8cfe3317cf875eecfc2d"
-dependencies = [
- "autocfg",
-]
+checksum = "38b58827f4464d87d377d175e90bf58eb00fd8716ff0a62f80356b5e61555d0d"
 
 [[package]]
 name = "smallvec"
-version = "1.11.0"
+version = "1.11.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "62bb4feee49fdd9f707ef802e22365a35de4b7b299de4763d44bfea899442ff9"
+checksum = "942b4a808e05215192e39f4ab80813e599068285906cc91aa64f923db842bd5a"
 
 [[package]]
 name = "smartstring"
@@ -2582,21 +2328,11 @@ dependencies = [
  "version_check",
 ]
 
-[[package]]
-name = "socket2"
-version = "0.4.9"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "64a4a911eed85daf18834cfaa86a79b7d266ff93ff5ba14005426219480ed662"
-dependencies = [
- "libc",
- "winapi",
-]
-
 [[package]]
 name = "sqlparser"
-version = "0.34.0"
+version = "0.38.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "37d3706eefb17039056234df6b566b0014f303f867f2656108334a55b8096f59"
+checksum = "0272b7bb0a225320170c99901b4b5fb3a4384e255a7f2cc228f61e2ba3893e75"
 dependencies = [
  "log",
 ]
@@ -2607,6 +2343,12 @@ version = "1.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "a2eb9349b6444b326872e140eb1cf5e7c522154d69e7a0ffb0fb81c06b37543f"
 
+[[package]]
+name = "streaming-iterator"
+version = "0.1.9"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "2b2231b7c3057d5e4ad0156fb3dc807d900806020c5ffa3ee6ff2c8c76fb8520"
+
 [[package]]
 name = "strength_reduce"
 version = "0.2.4"
@@ -2643,21 +2385,21 @@ dependencies = [
 
 [[package]]
 name = "strum"
-version = "0.24.1"
+version = "0.25.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "063e6045c0e62079840579a7e47a355ae92f60eb74daaf156fb1e84ba164e63f"
+checksum = "290d54ea6f91c969195bdbcd7442c8c2a2ba87da8bf60a7ee86a235d4bc1e125"
 
 [[package]]
 name = "strum_macros"
-version = "0.24.3"
+version = "0.25.3"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1e385be0d24f186b4ce2f9982191e7101bb737312ad61c1f2f984f34bcf85d59"
+checksum = "23dc1fa9ac9c169a78ba62f0b841814b7abae11bdd047b9c58f893439e309ea0"
 dependencies = [
  "heck",
  "proc-macro2",
  "quote",
  "rustversion",
- "syn 1.0.109",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -2673,9 +2415,9 @@ dependencies = [
 
 [[package]]
 name = "syn"
-version = "2.0.32"
+version = "2.0.38"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "239814284fd6f1a4ffe4ca893952cdd93c224b6a1571c9a9eadd670295c0c9e2"
+checksum = "e96b79aaa137db8f61e26363a0c9b47d8b4ec75da28b7d1d614c2303e232408b"
 dependencies = [
  "proc-macro2",
  "quote",
@@ -2684,9 +2426,9 @@ dependencies = [
 
 [[package]]
 name = "sysinfo"
-version = "0.29.4"
+version = "0.29.10"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "751e810399bba86e9326f5762b7f32ac5a085542df78da6a78d94e07d14d7c11"
+checksum = "0a18d114d420ada3a891e6bc8e96a2023402203296a47cdd65083377dad18ba5"
 dependencies = [
  "cfg-if",
  "core-foundation-sys",
@@ -2728,21 +2470,20 @@ checksum = "55937e1799185b12863d447f42597ed69d9928686b8d88a1df17376a097d8369"
 
 [[package]]
 name = "target-features"
-version = "0.1.4"
+version = "0.1.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "06f6b473c37f9add4cf1df5b4d66a8ef58ab6c895f1a3b3f949cf3e21230140e"
+checksum = "cfb5fa503293557c5158bd215fdc225695e567a77e453f5d4452a50a193969bd"
 
 [[package]]
 name = "tempfile"
-version = "3.6.0"
+version = "3.8.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "31c0432476357e58790aaa47a8efb0c5138f137343f3b5f23bd36a27e3b0a6d6"
+checksum = "7ef1adac450ad7f4b3c28589471ade84f25f731a7a0fe30d71dfa9f60fd808e5"
 dependencies = [
- "autocfg",
  "cfg-if",
  "fastrand",
- "redox_syscall 0.3.5",
- "rustix 0.37.23",
+ "redox_syscall",
+ "rustix",
  "windows-sys",
 ]
 
@@ -2761,28 +2502,28 @@ version = "0.3.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "21bebf2b7c9e0a515f6e0f8c51dc0f8e4696391e6f1ff30379559f8365fb0df7"
 dependencies = [
- "rustix 0.38.19",
+ "rustix",
  "windows-sys",
 ]
 
 [[package]]
 name = "thiserror"
-version = "1.0.43"
+version = "1.0.50"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a35fc5b8971143ca348fa6df4f024d4d55264f3468c71ad1c2f365b0a4d58c42"
+checksum = "f9a7210f5c9a7156bb50aa36aed4c95afb51df0df00713949448cf9e97d382d2"
 dependencies = [
  "thiserror-impl",
 ]
 
 [[package]]
 name = "thiserror-impl"
-version = "1.0.43"
+version = "1.0.50"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "463fe12d7993d3b327787537ce8dd4dfa058de32fc2b195ef3cde03dc4771e8f"
+checksum = "266b2e40bc00e5a6c09c3584011e08b06f123c00362c92b975ba9843aaaa14b8"
 dependencies = [
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -2830,21 +2571,6 @@ dependencies = [
  "time-core",
 ]
 
-[[package]]
-name = "tokio"
-version = "1.29.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "532826ff75199d5833b9d2c5fe410f29235e25704ee5f0ef599fb51c21f4a4da"
-dependencies = [
- "autocfg",
- "backtrace",
- "libc",
- "mio",
- "pin-project-lite",
- "socket2",
- "windows-sys",
-]
-
 [[package]]
 name = "tracing"
 version = "0.1.40"
@@ -2864,7 +2590,7 @@ checksum = "34704c8d6ebcbc939824180af020566b01a7c01f80641264eba0999f6c2b6be7"
 dependencies = [
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
 ]
 
 [[package]]
@@ -2879,12 +2605,12 @@ dependencies = [
 
 [[package]]
 name = "tracing-log"
-version = "0.1.3"
+version = "0.1.4"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "78ddad33d2d10b1ed7eb9d1f518a5674713876e97e5bb9b7345a7984fbb4f922"
+checksum = "f751112709b4e791d8ce53e32c4ed2d353565a795ce84da2285393f41557bdf2"
 dependencies = [
- "lazy_static",
  "log",
+ "once_cell",
  "tracing-core",
 ]
 
@@ -2908,9 +2634,9 @@ dependencies = [
 
 [[package]]
 name = "typenum"
-version = "1.16.0"
+version = "1.17.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "497961ef93d974e23eb6f433eb5fe1b7930b659f06d12dec6fc44a8f554c0bba"
+checksum = "42ff0bf0c66b8238c6f3b578df37d0b7848e55df8577b3f74f92a69acceeb825"
 
 [[package]]
 name = "ucd-trie"
@@ -2981,22 +2707,10 @@ dependencies = [
  "once_cell",
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
  "wasm-bindgen-shared",
 ]
 
-[[package]]
-name = "wasm-bindgen-futures"
-version = "0.4.37"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "c02dbc21516f9f1f04f187958890d7e6026df8d16540b7ad9492bc34a67cea03"
-dependencies = [
- "cfg-if",
- "js-sys",
- "wasm-bindgen",
- "web-sys",
-]
-
 [[package]]
 name = "wasm-bindgen-macro"
 version = "0.2.87"
@@ -3015,7 +2729,7 @@ checksum = "54681b18a46765f095758388f2d0cf16eb8d4169b639ab575a8f5693af210c7b"
 dependencies = [
  "proc-macro2",
  "quote",
- "syn 2.0.32",
+ "syn 2.0.38",
  "wasm-bindgen-backend",
  "wasm-bindgen-shared",
 ]
@@ -3026,31 +2740,6 @@ version = "0.2.87"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "ca6ad05a4870b2bf5fe995117d3728437bd27d7cd5f06f13c17443ef369775a1"
 
-[[package]]
-name = "wasm-timer"
-version = "0.2.5"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "be0ecb0db480561e9a7642b5d3e4187c128914e58aa84330b9493e3eb68c5e7f"
-dependencies = [
- "futures",
- "js-sys",
- "parking_lot 0.11.2",
- "pin-utils",
- "wasm-bindgen",
- "wasm-bindgen-futures",
- "web-sys",
-]
-
-[[package]]
-name = "web-sys"
-version = "0.3.64"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9b85cbef8c220a6abc02aefd892dfc0fc23afb1c6a426316ec33253a3877249b"
-dependencies = [
- "js-sys",
- "wasm-bindgen",
-]
-
 [[package]]
 name = "which"
 version = "5.0.0"
@@ -3060,7 +2749,7 @@ dependencies = [
  "either",
  "home",
  "once_cell",
- "rustix 0.38.19",
+ "rustix",
  "windows-sys",
 ]
 
@@ -3096,10 +2785,10 @@ source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "712e227841d057c1ee1cd2fb22fa7e5a5461ae8e48fa2ca79ec42cfc1931183f"
 
 [[package]]
-name = "windows"
-version = "0.48.0"
+name = "windows-core"
+version = "0.51.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e686886bc078bc1b0b600cac0147aadb815089b6e4da64016cbd754b6342700f"
+checksum = "f1f8cf84f35d2db49a46868f947758c7a1138116f7fac3bc844f43ade1292e64"
 dependencies = [
  "windows-targets",
 ]
@@ -3115,9 +2804,9 @@ dependencies = [
 
 [[package]]
 name = "windows-targets"
-version = "0.48.1"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "05d4b17490f70499f20b9e791dcf6a299785ce8af4d709018206dc5b4953e95f"
+checksum = "9a2fa6e2155d7247be68c096456083145c183cbbbc2764150dda45a87197940c"
 dependencies = [
  "windows_aarch64_gnullvm",
  "windows_aarch64_msvc",
@@ -3130,45 +2819,45 @@ dependencies = [
 
 [[package]]
 name = "windows_aarch64_gnullvm"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "91ae572e1b79dba883e0d315474df7305d12f569b400fcf90581b06062f7e1bc"
+checksum = "2b38e32f0abccf9987a4e3079dfb67dcd799fb61361e53e2882c3cbaf0d905d8"
 
 [[package]]
 name = "windows_aarch64_msvc"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b2ef27e0d7bdfcfc7b868b317c1d32c641a6fe4629c171b8928c7b08d98d7cf3"
+checksum = "dc35310971f3b2dbbf3f0690a219f40e2d9afcf64f9ab7cc1be722937c26b4bc"
 
 [[package]]
 name = "windows_i686_gnu"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "622a1962a7db830d6fd0a69683c80a18fda201879f0f447f065a3b7467daa241"
+checksum = "a75915e7def60c94dcef72200b9a8e58e5091744960da64ec734a6c6e9b3743e"
 
 [[package]]
 name = "windows_i686_msvc"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "4542c6e364ce21bf45d69fdd2a8e455fa38d316158cfd43b3ac1c5b1b19f8e00"
+checksum = "8f55c233f70c4b27f66c523580f78f1004e8b5a8b659e05a4eb49d4166cca406"
 
 [[package]]
 name = "windows_x86_64_gnu"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ca2b8a661f7628cbd23440e50b05d705db3686f894fc9580820623656af974b1"
+checksum = "53d40abd2583d23e4718fddf1ebec84dbff8381c07cae67ff7768bbf19c6718e"
 
 [[package]]
 name = "windows_x86_64_gnullvm"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7896dbc1f41e08872e9d5e8f8baa8fdd2677f29468c4e156210174edc7f7b953"
+checksum = "0b7b52767868a23d5bab768e390dc5f5c55825b6d30b86c844ff2dc7414044cc"
 
 [[package]]
 name = "windows_x86_64_msvc"
-version = "0.48.0"
+version = "0.48.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1a515f5799fe4961cb532f983ce2b23082366b898e52ffbce459c86f67c8378a"
+checksum = "ed94fce61571a4006852b7389a063ab983c02eb1bb37b47f8272ce92d06d9538"
 
 [[package]]
 name = "wyz"
@@ -3181,9 +2870,9 @@ dependencies = [
 
 [[package]]
 name = "xxhash-rust"
-version = "0.8.6"
+version = "0.8.7"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "735a71d46c4d68d71d4b24d03fdc2b98e38cea81730595801db779c04fe80d70"
+checksum = "9828b178da53440fa9c766a3d2f73f7cf5d0ac1fe3980c1e5018d899fd19e07b"
 
 [[package]]
 name = "xz2"
@@ -3212,32 +2901,50 @@ dependencies = [
  "winapi",
 ]
 
+[[package]]
+name = "zerocopy"
+version = "0.7.18"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "ede7d7c7970ca2215b8c1ccf4d4f354c4733201dfaaba72d44ae5b37472e4901"
+dependencies = [
+ "zerocopy-derive",
+]
+
+[[package]]
+name = "zerocopy-derive"
+version = "0.7.18"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "4b27b1bb92570f989aac0ab7e9cbfbacdd65973f7ee920d9f0e71ebac878fd0b"
+dependencies = [
+ "proc-macro2",
+ "quote",
+ "syn 2.0.38",
+]
+
 [[package]]
 name = "zstd"
-version = "0.12.3+zstd.1.5.2"
+version = "0.13.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "76eea132fb024e0e13fd9c2f5d5d595d8a967aa72382ac2f9d39fcc95afd0806"
+checksum = "bffb3309596d527cfcba7dfc6ed6052f1d39dfbd7c867aa2e865e4a449c10110"
 dependencies = [
  "zstd-safe",
 ]
 
 [[package]]
 name = "zstd-safe"
-version = "6.0.5+zstd.1.5.4"
+version = "7.0.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d56d9e60b4b1758206c238a10165fbcae3ca37b01744e394c463463f6529d23b"
+checksum = "43747c7422e2924c11144d5229878b98180ef8b06cca4ab5af37afc8a8d8ea3e"
 dependencies = [
- "libc",
  "zstd-sys",
 ]
 
 [[package]]
 name = "zstd-sys"
-version = "2.0.8+zstd.1.5.5"
+version = "2.0.9+zstd.1.5.5"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "5556e6ee25d32df2586c098bbfa278803692a20d0ab9565e049480d52707ec8c"
+checksum = "9e16efa8a874a0481a574084d34cc26fdb3b99627480f785888deb6386506656"
 dependencies = [
  "cc",
- "libc",
  "pkg-config",
 ]
diff --git a/Cargo.toml b/Cargo.toml
index 3ae70c7..3e364b5 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -34,7 +34,7 @@ categories = ["command-line-utilities", "science"]
 [dependencies]
 seq_geom_parser = { git = "https://github.com/COMBINE-lab/seq_geom_parser", branch = "dev", version = "0.3.0" }
 seq_geom_xform = { git = "https://github.com/COMBINE-lab/seq_geom_xform", branch = "dev", version = "0.4.0" }
-roers = { git = "https://github.com/COMBINE-lab/roers", branch = "main", version = "0.2.0" }
+roers = { git = "https://github.com/COMBINE-lab/roers", branch = "main", version = "0.3.0" }
 anyhow = "^1.0"
 clap = { version = "4.4.6", features = ["derive", "cargo", "deprecated", "wrap_help", "help", "usage", "error-context"] } 
 cmd_lib = "^1.6.0"