sepsis patients according to sepsis-3

[houraniiiii]

Hello,

I’m currently working with the eICU database and need to identify sepsis patients according to Sepsis-3 criteria. Could you provide details on any available codes or tables that can help specify sepsis cases based on Sepsis-3 guidelines?

I found the ricu R package, which includes functions to identify Sepsis-3 patients across various ICU databases, including eICU. However, this package relies on fluid sampling data, which appears to be incomplete in the eICU dataset. I noticed that one study (1) defined Sepsis-3 as the concurrent use of multiple antibiotics, addressing this data gap. There are several studies using eICU data to study Sepsis-3 patients, but they often include a larger cohort of sepsis cases than the number of available fluid samples, and they typically lack code or detailed explanations for their methods.

Thank you!

(1) Moor, Michael et al. “Predicting sepsis using deep learning across international sites: a retrospective development and validation study.” EClinicalMedicine, vol. 62, 102124, 11 Aug. 2023, doi:10.1016/j.eclinm.2023.102124