For now QUsb2Snes Linux integration is pretty bad (especially configuration file)
You need the developpment files for Qt 5.8 or supperior. You will need the developplent files for websocket and serialport libraries that goes with your Qt version You can etheir use the Qbs build tool or the regular qmake build too to build it. QMake is simpler to use.
qmake QUsb2snes.pro CONFIG+='release'
make
Then start the QUsb2Snes binart from the release
directory that is created.
To make your sd2snes device work, you will need to set some tty setting
stty -F /dev/ttyACM0 0:0:cbd:0:3:1c:7f:15:4:5:40:0:11:13:1a:0:12:f:17:16:0:0:0:0:0:0:0:0:0:0:0:0:0:0:0:0
Replace /dev/ttyACM0
by the correct device.