diff --git a/numba_cuda/numba/cuda/cudadrv/nvrtc.py b/numba_cuda/numba/cuda/cudadrv/nvrtc.py
index 0178345..9a1ae74 100644
--- a/numba_cuda/numba/cuda/cudadrv/nvrtc.py
+++ b/numba_cuda/numba/cuda/cudadrv/nvrtc.py
@@ -3,6 +3,7 @@
 from numba.core import config
 from numba.cuda.cudadrv.error import (NvrtcError, NvrtcCompilationError,
                                       NvrtcSupportError)
+from cuda.cuda.cudadrv.driver import get_version
 
 import functools
 import os
@@ -62,6 +63,14 @@ class NVRTC:
     NVVM interface. Initialization is protected by a lock and uses the standard
     (for Numba) open_cudalib function to load the NVRTC library.
     """
+
+    _CU12ONLY_PROTOTYPES = {
+        # nvrtcResult nvrtcGetLTOIRSize(nvrtcProgram prog, size_t *ltoSizeRet);
+        "nvrtcGetLTOIRSize": (nvrtc_result, nvrtc_program, POINTER(c_size_t)),
+        # nvrtcResult nvrtcGetLTOIR(nvrtcProgram prog, char *lto);
+        "nvrtcGetLTOIR": (nvrtc_result, nvrtc_program, c_char_p)
+    }
+
     _PROTOTYPES = {
         # nvrtcResult nvrtcVersion(int *major, int *minor)
         'nvrtcVersion': (nvrtc_result, POINTER(c_int), POINTER(c_int)),
@@ -84,10 +93,6 @@ class NVRTC:
         'nvrtcGetPTXSize': (nvrtc_result, nvrtc_program, POINTER(c_size_t)),
         # nvrtcResult nvrtcGetPTX(nvrtcProgram prog, char *ptx);
         'nvrtcGetPTX': (nvrtc_result, nvrtc_program, c_char_p),
-        # nvrtcResult nvrtcGetLTOIRSize(nvrtcProgram prog, size_t *ltoSizeRet);
-        "nvrtcGetLTOIRSize": (nvrtc_result, nvrtc_program, POINTER(c_size_t)),
-        # nvrtcResult nvrtcGetLTOIR(nvrtcProgram prog, char *lto);
-        "nvrtcGetLTOIR": (nvrtc_result, nvrtc_program, c_char_p),
         # nvrtcResult nvrtcGetCUBINSize(nvrtcProgram prog,
         #                               size_t *cubinSizeRet);
         'nvrtcGetCUBINSize': (nvrtc_result, nvrtc_program, POINTER(c_size_t)),
@@ -101,6 +106,9 @@ class NVRTC:
         'nvrtcGetProgramLog': (nvrtc_result, nvrtc_program, c_char_p),
     }
 
+    if get_version() >= (12, 0):
+        _PROTOTYPES |= _CU12ONLY_PROTOTYPES
+
     # Singleton reference
     __INSTANCE = None