forked from ucscCancer/pindel-tool
-
Notifications
You must be signed in to change notification settings - Fork 3
/
pindel-somatic.template
44 lines (44 loc) · 4.37 KB
/
pindel-somatic.template
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
{
"tumor" : {
"class" : "File",
"path": "</full/file/path>" # Required file; replace '</full/file/path>' with full path to tumor DNA BAM file [e.g., /my/path/to/tumor.bam]
},
"normal" : {
"class" : "File",
"path" : "</full/file/path>" # Required file; replace '</full/file/path>' with full path to normal DNA BAM file [e.g., /my/path/to/normal.bam]
},
"reference": {
"class" : "File",
"path": "</full/file/path>" # Required file; replace '</full/file/path>' with full path to reference FASTA [e.g., /my/path/to/genome.fa.gz]
},
"centromere" : {
"class" : "File",
"path" : "</full/file/path>" # Required file; replace '</full/file/path>' with centromere location BED file [e.g., /my/path/to/centromere.bed]
},
"additional_mismatch" : null, # Optional integer; only map part of a read to the reference genome if there are no other candidate positions with no more than this number of mismatches position (larger values are more accurate but less sensitive); 'null' defaults to '1'
"outputRawFile" : null, # Optional string; name of raw output file; 'null' defaults to 'pindel.raw'
"outputSomaticVcfFile" : null, # Optional string; name of somatic VCF output file; 'null' defaults to 'pindel_somatic.vcf'
"outputVcfFile" : null, # Optional string; name of full VCF output file; 'null' defaults to 'pindel.vcf'
"procs" : null, # Optional integer; number of threads to run Pindel; 'null' defaults to '2'
"balance_cutoff" : null, # Optional integer; number of bases of an SV above which a more stringent filter is applied; 'null' defaults to '100'
"max_range_index" : null, # Optional integer; maximum size of structural variations to be detected; 'null' defaults to '4'
"maximum_allowed_mismatch_rate" : null, # Optional float; only reads with fewer mismatches with the reference genome than this fraction will be considered; 'null' defaults to '0.02'
"min_inversion_size" : null, # Optional integer; only report inversions greater than this number of bases; 'null' defaults to '50'
"min_num_matched_bases" : null, # Optional integer; only consider reads as evidence if they map with more than this number of bases to the reference; 'null' defaults to '30'
"min_perfect_match_around_BP" : null, # Optional integer; there should at least be this number of perfectly matching bases between read and reference where the read is split into two; 'null' defaults to '3'
"minimum_support_for_event" : null, # Optional integer; minimum supporting reads to call an event; 'null' defaults to '1'
"normal_insert_size" : null, # Optional integer; insert size of normal reads
"referenceName" : null, # Optional string; Short name for reference file; 'null' defaults to 'HG19'
"report_breakpoints" : null, # Optional boolean; replace 'null' with 'true' to report breakpoints; 'null' defaults to 'false'
"report_duplications" : null, # Optional boolean; replace 'null' with 'true' to report duplications; 'null' defaults to 'false'
"report_inversions" : null, # Optional boolean; replace 'null' with 'true' to report inversions; 'null' defaults to 'false'
"report_long_insertions" : null, # Optional boolean; replace 'null' with 'true' to enable report long insertions; 'null' defaults to 'false'
"report_only_close_mapped_reads" : null, # Optional boolean; replace 'null' with 'true' to enable report only closely mapped reads; 'null' defaults to 'false'
"sensitivity" : null, # Optional float; 'null' defaults to '0.95'
"sequencing_error_rate" : null, # Optional float; 'null' defaults to '0.01'
"somatic_cov" : null, # Optional integer; 'null' defaults to '20'
"somatic_hom" : null, # Optional integer; 'null' defaults to '6'
"somatic_vaf" : null, # Optional float; 'null' defaults to '0.08'
"tumor_insert_size" : null, # Optional integer; insert size of tumor reads
"window_size" : null # Optional float; 'null' defaults to '5.0'
}