diff --git a/qiskit/transpiler/passes/synthesis/unitary_synthesis.py b/qiskit/transpiler/passes/synthesis/unitary_synthesis.py
index d2a037a5034d..a30411d16a93 100644
--- a/qiskit/transpiler/passes/synthesis/unitary_synthesis.py
+++ b/qiskit/transpiler/passes/synthesis/unitary_synthesis.py
@@ -49,7 +49,6 @@
     CZGate,
     RXXGate,
     RZXGate,
-    RZZGate,
     ECRGate,
 )
 from qiskit.transpiler.passes.synthesis import plugin
@@ -745,8 +744,6 @@ def _replace_parameterized_gate(op):
                 op = RXXGate(pi / 2)
             elif isinstance(op, RZXGate) and isinstance(op.params[0], Parameter):
                 op = RZXGate(pi / 4)
-            elif isinstance(op, RZZGate) and isinstance(op.params[0], Parameter):
-                op = RZZGate(pi / 2)
             return op
 
         try:
diff --git a/test/python/transpiler/test_basis_translator.py b/test/python/transpiler/test_basis_translator.py
index cd94c474d01f..24e5e68ba987 100644
--- a/test/python/transpiler/test_basis_translator.py
+++ b/test/python/transpiler/test_basis_translator.py
@@ -16,7 +16,6 @@
 import os
 
 from numpy import pi
-import scipy
 
 from qiskit import QuantumRegister, ClassicalRegister, QuantumCircuit
 from qiskit import transpile
@@ -34,17 +33,13 @@
     XGate,
     SXGate,
     CXGate,
-    RXGate,
-    RZZGate,
 )
 from qiskit.converters import circuit_to_dag, dag_to_circuit, circuit_to_instruction
 from qiskit.exceptions import QiskitError
-from qiskit.providers.fake_provider import GenericBackendV2
 from qiskit.quantum_info import Operator
 from qiskit.transpiler.target import Target, InstructionProperties
 from qiskit.transpiler.exceptions import TranspilerError
 from qiskit.transpiler.passes.basis import BasisTranslator, UnrollCustomDefinitions
-from qiskit.transpiler.preset_passmanagers import generate_preset_pass_manager
 from qiskit.circuit.library.standard_gates.equivalence_library import (
     StandardEquivalenceLibrary as std_eqlib,
 )
@@ -1227,48 +1222,3 @@ def __init__(self):
 
         out = BasisTranslator(eq_lib, {"my_h", "my_cx"}, target)(qc)
         self.assertEqual(out, expected)
-
-    def test_fractional_gate_in_basis_from_string(self):
-        """Test transpiling with RZZ in basis with only basis_gates option."""
-        num_qubits = 2
-        seed = 9169
-        basis_gates = ["rz", "rx", "rzz"]
-        qc = QuantumCircuit(num_qubits)
-        mat = scipy.stats.unitary_group.rvs(2**num_qubits, random_state=seed)
-        qc.unitary(mat, range(num_qubits))
-        pm = generate_preset_pass_manager(
-            optimization_level=1, basis_gates=basis_gates, seed_transpiler=134
-        )
-        cqc = pm.run(qc)
-        self.assertEqual(Operator(qc), Operator(cqc))
-
-    def test_fractional_gate_in_basis_from_backendv2(self):
-        """Test transpiling with RZZ in basis of backendv2."""
-        num_qubits = 2
-        seed = 9169
-        basis_gates = ["rz", "rx", "rzz"]
-        qc = QuantumCircuit(num_qubits)
-        mat = scipy.stats.unitary_group.rvs(2**num_qubits, random_state=seed)
-        qc.unitary(mat, range(num_qubits))
-        backend = GenericBackendV2(num_qubits, basis_gates=basis_gates)
-        target = backend.target
-        pm = generate_preset_pass_manager(optimization_level=1, target=target, seed_transpiler=134)
-        cqc = pm.run(qc)
-        self.assertEqual(Operator(qc), Operator.from_circuit(cqc))
-
-    def test_fractional_gate_in_basis_from_custom_target(self):
-        """Test transpiling with RZZ in basis of custom target."""
-        num_qubits = 2
-        seed = 9169
-        qc = QuantumCircuit(num_qubits)
-        mat = scipy.stats.unitary_group.rvs(2**num_qubits, random_state=seed)
-        qc.unitary(mat, range(num_qubits))
-        target = Target()
-        target.add_instruction(RZGate(self.theta), {(i,): None for i in range(qc.num_qubits)})
-        target.add_instruction(RXGate(self.phi), {(i,): None for i in range(qc.num_qubits)})
-        target.add_instruction(
-            RZZGate(self.lam), {(i, i + 1): None for i in range(qc.num_qubits - 1)}
-        )
-        pm = generate_preset_pass_manager(optimization_level=1, target=target, seed_transpiler=134)
-        cqc = pm.run(qc)
-        self.assertEqual(Operator(qc), Operator.from_circuit(cqc))