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CHIIMP should support IUPAC codes for ambiguous nucleotides in primer sequences in order to recognize multiple sets of possible primers for a single locus.
The text was updated successfully, but these errors were encountered:
This is probably a good opportunity to move away from character vectors to support these sorts of features. Biostrings supports ambiguous matches via IUPAC codes easily:
> Biostrings::vmatchPattern(
+ "RCTG",
+ Biostrings::DNAStringSet(c("ACTGAAAATCAA", "GCTGAGGCTCAA", "TCTGAAAATCAA")),
+ fixed = FALSE)
MIndex object of length 3
[[1]]
IRanges of length 1
start end width
[1] 1 4 4
[[2]]
IRanges of length 1
start end width
[1] 1 4 4
[[3]]
IRanges of length 0
CHIIMP should support IUPAC codes for ambiguous nucleotides in primer sequences in order to recognize multiple sets of possible primers for a single locus.
The text was updated successfully, but these errors were encountered: