diff --git a/setup.py b/setup.py
index 2aca048dcd4fb9..bfd0c50c9e9be3 100755
--- a/setup.py
+++ b/setup.py
@@ -544,8 +544,7 @@ def srcpath(name=None, suffix='.pyx', subdir='src'):
     '_libs.parsers': {
         'pyxfile': '_libs/parsers',
         'depends': ['pandas/_libs/src/parser/tokenizer.h',
-                    'pandas/_libs/src/parser/io.h',
-                    'pandas/_libs/src/numpy_helper.h'],
+                    'pandas/_libs/src/parser/io.h'],
         'sources': ['pandas/_libs/src/parser/tokenizer.c',
                     'pandas/_libs/src/parser/io.c']},
     '_libs.reduction': {