From 9d3818be28bbd237448a930a17b35a9330a51c50 Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Wed, 22 Mar 2023 11:29:38 +0100 Subject: [PATCH 1/2] fix: refine GPRs for Pyrroline-5-carboxylate reductase --- model/Human-GEM.yml | 8 ++++---- 1 file changed, 4 insertions(+), 4 deletions(-) diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index 191d7c8d..714d09b6 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -77153,7 +77153,7 @@ - MAM02770c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811 or ENSG00000183010" + - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.5.1.2" @@ -77172,7 +77172,7 @@ - MAM02770c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811 or ENSG00000183010" + - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.5.1.2" @@ -77191,7 +77191,7 @@ - MAM02770m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811 or ENSG00000183010" + - gene_reaction_rule: "ENSG00000143811 or ENSG00000183010" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.5.1.2" @@ -78831,7 +78831,7 @@ - MAM02770m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000104524 or ENSG00000143811 or ENSG00000183010" + - gene_reaction_rule: "ENSG00000143811 or ENSG00000183010" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.5.1.2" From 96a672e38a1c0fb3c88b39de18bcaefe7c8e1dbe Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Wed, 22 Mar 2023 11:51:55 +0100 Subject: [PATCH 2/2] fix-met: rename MAM01939 from G3P to D-glyceraldehyde 3-phosphate - rename metabolite as discussed in #500 --- model/Human-GEM.yml | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index 714d09b6..09c704b0 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -26446,7 +26446,7 @@ - metFrom: "HMRdatabase" - !!omap - id: "MAM01939c" - - name: "GAP" + - name: "D-glyceraldehyde 3-phosphate" - compartment: "c" - formula: "C3H5O6P" - charge: -2