diff --git a/.github/workflows/commentsFromTests.md b/.github/workflows/commentsFromTests.md
new file mode 100644
index 00000000..dd2ba900
--- /dev/null
+++ b/.github/workflows/commentsFromTests.md
@@ -0,0 +1,7 @@
+This PR has been [automatically tested with GH Actions](https://github.com/SysBioChalmers/Human-GEM/actions/runs/{GH_ACTION_RUN}). Here is the output of the gene essentiality test:
+
+<pre>
+{TEST_RESULTS}
+</pre>
+
+> _Note: In the case of multiple test runs, this post will be edited._
diff --git a/.github/workflows/gene-essentiality.yml b/.github/workflows/gene-essentiality.yml
new file mode 100644
index 00000000..169efc71
--- /dev/null
+++ b/.github/workflows/gene-essentiality.yml
@@ -0,0 +1,33 @@
+name: Check gene essentiality with Hart 2015
+
+on:
+  pull_request:
+    branches:
+      - "main"
+      - "develop"
+
+jobs:
+  check-metabolictasks:
+    runs-on: self-hosted
+
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v3
+
+      - name: Run gene essentiality
+        id: essentiality
+        run: |
+          TEST_RESULTS=$(/usr/local/bin/matlab -nodisplay -nosplash -nodesktop -r "addpath(genpath('.')); ihuman = importYaml('Human-GEM.yml'); taskStruct = parseTaskList('data/metabolicTasks/metabolicTasks_Essential.txt'); eGenes = estimateEssentialGenes(ihuman, 'Hart2015_RNAseq.txt', taskStruct); disp(evaluateHart2015Essentiality(eGenes));" | awk 'NR>9 && !/^\.+/')
+          PARSED_RESULTS="${TEST_RESULTS//'%'/'%25'}"
+          PARSED_RESULTS="${PARSED_RESULTS//$'\n'/'<br>'}"
+          PARSED_RESULTS="${PARSED_RESULTS//$'\r'/'<br>'}"
+          echo "results=$PARSED_RESULTS" >> $GITHUB_OUTPUT
+
+      - name: Post comment
+        uses: NejcZdovc/comment-pr@v2
+        with:
+          file: "commentsFromTests.md"
+        env:
+          GITHUB_TOKEN: ${{secrets.GITHUB_TOKEN}}
+          TEST_RESULTS: ${{steps.essentiality.outputs.results}}
+          GH_ACTION_RUN: ${{github.run_id}}