diff --git a/README.md b/README.md
index 2217e3b2..45b1f4e1 100644
--- a/README.md
+++ b/README.md
@@ -311,6 +311,32 @@ bigquery://host:port/projectid/location/dataset?disable_auth=true
 
 `disable_auth` (optional) - Pass `true` to skip Authentication, use only for testing and connecting to emulator.
 
+#### Spanner (PostgreSQL Interface)
+
+Spanner support is currently limited to databases using the [PostgreSQL Dialect](https://cloud.google.com/spanner/docs/postgresql-interface), which must be chosen during database creation. For future Spanner with GoogleSQL support, see [this discussion](https://github.com/amacneil/dbmate/discussions/369).
+
+Spanner with the Postgres interface requires that the [PGAdapter](https://cloud.google.com/spanner/docs/pgadapter) is running. Use the following format for `DATABASE_URL`, with the host and port set to where the PGAdapter is running:
+
+```shell
+DATABASE_URL="spanner-postgres://127.0.0.1:5432/database_name?sslmode=disable"
+```
+
+Note that specifying a username and password is not necessary, as authentication is handled by the PGAdapter (they will be ignored by the PGAdapter if specified).
+
+Other options of the [postgres driver](#postgresql) are supported.
+
+Spanner also doesn't allow DDL to be executed inside explicit transactions. You must therefore specify `transaction:false` on migrations that include DDL:
+
+```sql
+-- migrate:up transaction:false
+CREATE TABLE ...
+
+-- migrate:down transaction:false
+DROP TABLE ...
+```
+
+Schema dumps are not currently supported, as `pg_dump` uses functions that are not provided by Spanner.
+
 ### Creating Migrations
 
 To create a new migration, run `dbmate new create_users_table`. You can name the migration anything you like. This will create a file `db/migrations/20151127184807_create_users_table.sql` in the current directory:
diff --git a/docker-compose.yml b/docker-compose.yml
index ecc07570..217ac70c 100644
--- a/docker-compose.yml
+++ b/docker-compose.yml
@@ -13,6 +13,7 @@ services:
       - clickhouse-cluster-01
       - clickhouse-cluster-02
       - bigquery
+      - spanner-emulator
     environment:
       CLICKHOUSE_TEST_URL: clickhouse://clickhouse:9000/dbmate_test
       CLICKHOUSE_CLUSTER_01_TEST_URL: clickhouse://ch-cluster-01:9000/dbmate_test
@@ -20,6 +21,7 @@ services:
       MYSQL_TEST_URL: mysql://root:root@mysql/dbmate_test
       POSTGRES_TEST_URL: postgres://postgres:postgres@postgres/dbmate_test?sslmode=disable
       BIGQUERY_TEST_URL: bigquery://test/us-east5/dbmate_test?disable_auth=true&endpoint=http%3A%2F%2Fbigquery%3A9050
+      SPANNER_POSTGRES_TEST_URL: spanner-postgres://spanner-emulator/dbmate_test?sslmode=disable
 
   dbmate:
     build:
@@ -69,3 +71,6 @@ services:
     image: ghcr.io/goccy/bigquery-emulator:0.4.4
     command: |
       --project=test --dataset=dbmate_test
+
+  spanner-emulator:
+    image: gcr.io/cloud-spanner-pg-adapter/pgadapter-emulator
diff --git a/pkg/driver/postgres/postgres.go b/pkg/driver/postgres/postgres.go
index 8f91a408..99f3fac7 100644
--- a/pkg/driver/postgres/postgres.go
+++ b/pkg/driver/postgres/postgres.go
@@ -20,6 +20,7 @@ func init() {
 	dbmate.RegisterDriver(NewDriver, "postgres")
 	dbmate.RegisterDriver(NewDriver, "postgresql")
 	dbmate.RegisterDriver(NewDriver, "redshift")
+	dbmate.RegisterDriver(NewDriver, "spanner-postgres")
 }
 
 // Driver provides top level database functions
@@ -73,17 +74,16 @@ func connectionString(u *url.URL) string {
 	}
 	if port == "" {
 		switch u.Scheme {
-		case "postgresql":
-			fallthrough
-		case "postgres":
-			port = "5432"
 		case "redshift":
 			port = "5439"
+		default:
+			port = "5432"
 		}
 	}
 
 	// generate output URL
 	out, _ := url.Parse(u.String())
+	// force scheme back to postgres if there was another postgres-compatible scheme
 	out.Scheme = "postgres"
 	out.Host = fmt.Sprintf("%s:%s", hostname, port)
 	out.RawQuery = query.Encode()
@@ -439,8 +439,8 @@ func (drv *Driver) quotedMigrationsTableNameParts(db dbutil.Transaction) (string
 		return "", "", err
 	}
 
-	// Quote identifiers for Redshift
-	if drv.databaseURL.Scheme == "redshift" {
+	// Quote identifiers for Redshift and Spanner
+	if drv.databaseURL.Scheme == "redshift" || drv.databaseURL.Scheme == "spanner-postgres" {
 		return pq.QuoteIdentifier(schema), pq.QuoteIdentifier(strings.Join(tableNameParts, ".")), nil
 	}
 
diff --git a/pkg/driver/postgres/postgres_test.go b/pkg/driver/postgres/postgres_test.go
index 9b15e65f..d2dc4709 100644
--- a/pkg/driver/postgres/postgres_test.go
+++ b/pkg/driver/postgres/postgres_test.go
@@ -30,6 +30,15 @@ func testRedshiftDriver(t *testing.T) *Driver {
 	return drv.(*Driver)
 }
 
+func testSpannerPostgresDriver(t *testing.T) *Driver {
+	// URL to the spanner pgadapter, or a locally-running spanner emulator with the pgadapter
+	u := dbtest.GetenvURLOrSkip(t, "SPANNER_POSTGRES_TEST_URL")
+	drv, err := dbmate.New(u).Driver()
+	require.NoError(t, err)
+
+	return drv.(*Driver)
+}
+
 func prepTestPostgresDB(t *testing.T) *sql.DB {
 	drv := testPostgresDriver(t)
 
@@ -64,6 +73,21 @@ func prepRedshiftTestDB(t *testing.T, drv *Driver) *sql.DB {
 	return db
 }
 
+func prepTestSpannerPostgresDB(t *testing.T, drv *Driver) *sql.DB {
+	// Spanner doesn't allow running `drop database`, so we just drop the migrations
+	// table instead
+	db, err := sql.Open("postgres", connectionString(drv.databaseURL))
+	require.NoError(t, err)
+
+	_, migrationsTable, err := drv.quotedMigrationsTableNameParts(db)
+	require.NoError(t, err)
+
+	_, err = db.Exec(fmt.Sprintf("drop table if exists %s", migrationsTable))
+	require.NoError(t, err)
+
+	return db
+}
+
 func TestGetDriver(t *testing.T) {
 	db := dbmate.New(dbtest.MustParseURL(t, "postgres://"))
 	drvInterface, err := db.Driver()
@@ -107,6 +131,7 @@ func TestConnectionString(t *testing.T) {
 		{"postgres://bob:secret@/foo?host=/var/run/postgresql", "postgres://bob:secret@:5432/foo?host=%2Fvar%2Frun%2Fpostgresql"},
 		// redshift default port is 5439, not 5432
 		{"redshift://myhost/foo", "postgres://myhost:5439/foo"},
+		{"spanner-postgres://myhost/foo", "postgres://myhost:5432/foo"},
 	}
 
 	for _, c := range cases {
@@ -420,6 +445,28 @@ func TestRedshiftCreateMigrationsTable(t *testing.T) {
 	})
 }
 
+func TestSpannerPostgresCreateMigrationsTable(t *testing.T) {
+	t.Run("default schema", func(t *testing.T) {
+		drv := testSpannerPostgresDriver(t)
+		db := prepTestSpannerPostgresDB(t, drv)
+		defer dbutil.MustClose(db)
+
+		// migrations table should not exist
+		count := 0
+		err := db.QueryRow("select count(*) from public.schema_migrations").Scan(&count)
+		require.Error(t, err, "migrations table exists when it shouldn't")
+		require.Contains(t, err.Error(), "pq: relation \"public.schema_migrations\" does not exist")
+
+		// create table
+		err = drv.CreateMigrationsTable(db)
+		require.NoError(t, err)
+
+		// migrations table should exist
+		err = db.QueryRow("select count(*) from public.schema_migrations").Scan(&count)
+		require.NoError(t, err)
+	})
+}
+
 func TestPostgresSelectMigrations(t *testing.T) {
 	drv := testPostgresDriver(t)
 	drv.migrationsTableName = "test_migrations"