diff --git a/CHANGES.md b/CHANGES.md
index cf78044ad1048..6963d9507cdfe 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -68,7 +68,7 @@
 
 ## New Features / Improvements
 
-* X feature added (Java/Python) ([#X](https://github.com/apache/beam/issues/X)).
+* Profiling of Cythonized code has been disabled by default. This might improve performance for some Python pipelines ([#30938](https://github.com/apache/beam/pull/30938)).
 * Bigtable enrichment handler now accepts a custom function to build a composite row key. (Python) ([#30974](https://github.com/apache/beam/issues/30975)).
 
 ## Breaking Changes
diff --git a/sdks/python/apache_beam/coders/coder_impl.pxd b/sdks/python/apache_beam/coders/coder_impl.pxd
index 0e6e31d0fc824..52889fa2fd923 100644
--- a/sdks/python/apache_beam/coders/coder_impl.pxd
+++ b/sdks/python/apache_beam/coders/coder_impl.pxd
@@ -15,7 +15,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 
 cimport cython
 
diff --git a/sdks/python/apache_beam/metrics/monitoring_infos.py b/sdks/python/apache_beam/metrics/monitoring_infos.py
index ae12c93a5718e..7bc7cced280c1 100644
--- a/sdks/python/apache_beam/metrics/monitoring_infos.py
+++ b/sdks/python/apache_beam/metrics/monitoring_infos.py
@@ -16,7 +16,6 @@
 #
 
 # cython: language_level=3
-# cython: profile=True
 
 # pytype: skip-file
 
diff --git a/sdks/python/apache_beam/runners/common.py b/sdks/python/apache_beam/runners/common.py
index 54d54402312d0..82ff939dbaede 100644
--- a/sdks/python/apache_beam/runners/common.py
+++ b/sdks/python/apache_beam/runners/common.py
@@ -14,7 +14,6 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 #
-# cython: profile=True
 # cython: language_level=3
 
 """Worker operations executor.
diff --git a/sdks/python/apache_beam/runners/worker/opcounters.py b/sdks/python/apache_beam/runners/worker/opcounters.py
index 8d9b36a1166f7..ba53cbcbce7f5 100644
--- a/sdks/python/apache_beam/runners/worker/opcounters.py
+++ b/sdks/python/apache_beam/runners/worker/opcounters.py
@@ -16,7 +16,6 @@
 #
 
 # cython: language_level=3
-# cython: profile=True
 
 """Counters collect the progress of the Worker for reporting to the service."""
 
diff --git a/sdks/python/apache_beam/runners/worker/operations.py b/sdks/python/apache_beam/runners/worker/operations.py
index bdb16a46aeea4..00a652c49e669 100644
--- a/sdks/python/apache_beam/runners/worker/operations.py
+++ b/sdks/python/apache_beam/runners/worker/operations.py
@@ -16,7 +16,6 @@
 #
 
 # cython: language_level=3
-# cython: profile=True
 
 """Worker operations executor."""
 
diff --git a/sdks/python/apache_beam/runners/worker/statesampler_fast.pyx b/sdks/python/apache_beam/runners/worker/statesampler_fast.pyx
index f0e1e6ccb5957..7c082b7a62269 100644
--- a/sdks/python/apache_beam/runners/worker/statesampler_fast.pyx
+++ b/sdks/python/apache_beam/runners/worker/statesampler_fast.pyx
@@ -15,7 +15,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 # cython: language_level=3
 
 """State sampler for tracking time spent in execution steps.
diff --git a/sdks/python/apache_beam/testing/fast_test_utils.pxd b/sdks/python/apache_beam/testing/fast_test_utils.pxd
index 5b27f8b8d42f6..f8868e842b4ae 100644
--- a/sdks/python/apache_beam/testing/fast_test_utils.pxd
+++ b/sdks/python/apache_beam/testing/fast_test_utils.pxd
@@ -15,7 +15,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 
 cimport libc.stdint
 
diff --git a/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pxd b/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pxd
index 3df1a85e3a216..deab8bb16d9a7 100644
--- a/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pxd
+++ b/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pxd
@@ -14,7 +14,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 
 """ For internal use only. No backwards compatibility guarantees."""
 
diff --git a/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pyx b/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pyx
index 6fa32c6fd5d91..c1b32356ed1ff 100644
--- a/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pyx
+++ b/sdks/python/apache_beam/transforms/cy_dataflow_distribution_counter.pyx
@@ -14,7 +14,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 # cython: language_level=3
 
 """ For internal use only. No backwards compatibility guarantees."""
diff --git a/sdks/python/apache_beam/utils/counters.pxd b/sdks/python/apache_beam/utils/counters.pxd
index dc38bfa615812..bb6788da88584 100644
--- a/sdks/python/apache_beam/utils/counters.pxd
+++ b/sdks/python/apache_beam/utils/counters.pxd
@@ -15,7 +15,6 @@
 # limitations under the License.
 #
 
-# cython: profile=True
 # cython: overflowcheck=True
 
 cdef class Counter(object):
diff --git a/sdks/python/apache_beam/utils/windowed_value.py b/sdks/python/apache_beam/utils/windowed_value.py
index 7bee17eb154ea..fb15d3778a6a0 100644
--- a/sdks/python/apache_beam/utils/windowed_value.py
+++ b/sdks/python/apache_beam/utils/windowed_value.py
@@ -22,7 +22,6 @@
 # editing this file as WindowedValues are created for every element for
 # every step in a Beam pipeline.
 
-# cython: profile=True
 # cython: language_level=3
 
 # pytype: skip-file