diff --git a/crates/ruff/resources/test/fixtures/pyupgrade/UP009_9.py b/crates/ruff/resources/test/fixtures/pyupgrade/UP009_9.py
new file mode 100644
index 0000000000000..fbfb852bf4d3c
--- /dev/null
+++ b/crates/ruff/resources/test/fixtures/pyupgrade/UP009_9.py
@@ -0,0 +1,7 @@
+x = 1 \
+  # coding=utf8
+x = 2
+
+"""
+Should not be modified due to continuation in preceding line
+"""
diff --git a/crates/ruff/src/rules/pyupgrade/mod.rs b/crates/ruff/src/rules/pyupgrade/mod.rs
index 89ef60d46ca78..e6ff0e751bd37 100644
--- a/crates/ruff/src/rules/pyupgrade/mod.rs
+++ b/crates/ruff/src/rules/pyupgrade/mod.rs
@@ -70,6 +70,7 @@ mod tests {
     #[test_case(Rule::UTF8EncodingDeclaration, Path::new("UP009_6.py"))]
     #[test_case(Rule::UTF8EncodingDeclaration, Path::new("UP009_7.py"))]
     #[test_case(Rule::UTF8EncodingDeclaration, Path::new("UP009_8.py"))]
+    #[test_case(Rule::UTF8EncodingDeclaration, Path::new("UP009_9.py"))]
     #[test_case(Rule::UnicodeKindPrefix, Path::new("UP025.py"))]
     #[test_case(Rule::UnnecessaryBuiltinImport, Path::new("UP029.py"))]
     #[test_case(Rule::UnnecessaryClassParentheses, Path::new("UP039.py"))]
diff --git a/crates/ruff/src/rules/pyupgrade/rules/unnecessary_coding_comment.rs b/crates/ruff/src/rules/pyupgrade/rules/unnecessary_coding_comment.rs
index c03d7c9fc0673..1d2b1d195ef0b 100644
--- a/crates/ruff/src/rules/pyupgrade/rules/unnecessary_coding_comment.rs
+++ b/crates/ruff/src/rules/pyupgrade/rules/unnecessary_coding_comment.rs
@@ -65,6 +65,17 @@ pub(crate) fn unnecessary_coding_comment(
                 continue;
             }
 
+            // Do not apply to lines with continuations; a fix will result in invalid syntax
+            // Ex)
+            // ```
+            // x = 1 \
+            //    # coding=utf8
+            // x = 2
+            // ```
+            if let Some(_) = indexer.preceded_by_continuations(line_range.start(), locator) {
+                continue;
+            }
+
             let mut diagnostic = Diagnostic::new(UTF8EncodingDeclaration, *comment_range);
             if settings.rules.should_fix(diagnostic.kind.rule()) {
                 diagnostic.set_fix(Fix::automatic(Edit::deletion(
diff --git a/crates/ruff/src/rules/pyupgrade/snapshots/ruff__rules__pyupgrade__tests__UP009_9.py.snap b/crates/ruff/src/rules/pyupgrade/snapshots/ruff__rules__pyupgrade__tests__UP009_9.py.snap
new file mode 100644
index 0000000000000..870ad3bf5d625
--- /dev/null
+++ b/crates/ruff/src/rules/pyupgrade/snapshots/ruff__rules__pyupgrade__tests__UP009_9.py.snap
@@ -0,0 +1,4 @@
+---
+source: crates/ruff/src/rules/pyupgrade/mod.rs
+---
+