diff --git a/app/generated_resources.grd b/app/generated_resources.grd
index 3bce8a32e5bb..5748c3fd175c 100644
--- a/app/generated_resources.grd
+++ b/app/generated_resources.grd
@@ -10935,6 +10935,9 @@ Please help our engineers fix this problem. Tell us what happened right before y
     <message name="IDS_SHOW_KALEIDOSCOPE" desc="Menu item to launch the Brave watch feature">
       Watch
     </message>
+    <message name="IDS_EXTENSION_PROMPT_WARNING_IPFS" desc="Permisson string for access to ipfs api.">
+      Publish and retrieve files from IPFS
+    </message>
 
     <!-- BraveLabs bubble -->
     <message name="IDS_CHROMELABS_RELAUNCH_BUTTON_LABEL" desc="Label on the button in the footer of the Brave Labs bubble which will relaunch the browser.">
diff --git a/chromium_src/chrome/common/DEPS b/chromium_src/chrome/common/DEPS
index 246eda060af2..0cd460876a8e 100644
--- a/chromium_src/chrome/common/DEPS
+++ b/chromium_src/chrome/common/DEPS
@@ -2,7 +2,9 @@ include_rules = [
   "+../../../../chrome/common",
   "+../../../../../chrome/common/importer",
   "+../../../../../chrome/common/media",
+  "+../../../../../../chrome/common/extensions/permissions",
   "+brave/common",
   "+chrome/common",
   "+components/version_info",
 ]
+6
\ No newline at end of file
diff --git a/chromium_src/chrome/common/extensions/permissions/chrome_api_permissions.cc b/chromium_src/chrome/common/extensions/permissions/chrome_api_permissions.cc
new file mode 100644
index 000000000000..7a69efeb2668
--- /dev/null
+++ b/chromium_src/chrome/common/extensions/permissions/chrome_api_permissions.cc
@@ -0,0 +1,56 @@
+/* Copyright (c) 2021 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at https://mozilla.org/MPL/2.0/. */
+
+#define GetPermissionInfos GetPermissionInfos_ChromiumImpl
+#include "../../../../../../chrome/common/extensions/permissions/chrome_api_permissions.cc"
+#undef GetPermissionInfos
+
+namespace extensions {
+namespace chrome_api_permissions {
+
+namespace {
+
+constexpr APIPermissionInfo::InitInfo brave_permissions_to_register[] = {
+    {APIPermission::kIpfs, "ipfs",
+     APIPermissionInfo::kFlagImpliesFullURLAccess}};
+
+// Merges Brave and Chrormium constant arrays to final list of permissions.
+template <typename T, size_t N>
+class PermissionsContainer {
+ public:
+  constexpr PermissionsContainer(base::span<const T> chromium,
+                                 base::span<const T> brave) {
+    CHECK(N == chromium.size() + brave.size());
+    size_t last_index = 0;
+    for (const auto& item : chromium) {
+      permissions_[last_index++] = item;
+    }
+    for (const auto& item : brave) {
+      permissions_[last_index++] = item;
+    }
+  }
+  base::span<const T> GetPermissionInfos() const {
+    return base::make_span(permissions_);
+  }
+
+ private:
+  T permissions_[N];
+};
+
+constexpr size_t PermissionsTotal = base::size(permissions_to_register) +
+                                    base::size(brave_permissions_to_register);
+
+const PermissionsContainer<APIPermissionInfo::InitInfo, PermissionsTotal>
+    final_permissions(base::make_span(permissions_to_register),
+                      base::make_span(brave_permissions_to_register));
+
+}  // namespace
+
+base::span<const APIPermissionInfo::InitInfo> GetPermissionInfos() {
+  return final_permissions.GetPermissionInfos();
+}
+
+}  // namespace chrome_api_permissions
+}  // namespace extensions
diff --git a/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.cc b/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.cc
new file mode 100644
index 000000000000..b5c79979c58b
--- /dev/null
+++ b/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.cc
@@ -0,0 +1,24 @@
+/* Copyright (c) 2021 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at https://mozilla.org/MPL/2.0/. */
+
+#include "chrome/common/extensions/permissions/chrome_permission_message_rules.h"
+#include "brave/grit/brave_generated_resources.h"
+
+#define GetAllRules GetAllRules_ChromiumImpl
+#include "../../../../../../chrome/common/extensions/permissions/chrome_permission_message_rules.cc"
+#undef GetAllRules
+
+namespace extensions {
+
+// static
+std::vector<ChromePermissionMessageRule>
+ChromePermissionMessageRule::GetAllRules() {
+  auto rules = ChromePermissionMessageRule::GetAllRules_ChromiumImpl();
+  rules.push_back(
+      {IDS_EXTENSION_PROMPT_WARNING_IPFS, {APIPermission::kIpfs}, {}});
+  return rules;
+}
+
+}  // namespace extensions
diff --git a/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.h b/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.h
new file mode 100644
index 000000000000..c17e8b179da2
--- /dev/null
+++ b/chromium_src/chrome/common/extensions/permissions/chrome_permission_message_rules.h
@@ -0,0 +1,15 @@
+/* Copyright (c) 2021 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at http://mozilla.org/MPL/2.0/. */
+
+#ifndef BRAVE_CHROMIUM_SRC_CHROME_COMMON_EXTENSIONS_PERMISSIONS_CHROME_PERMISSION_MESSAGE_RULES_H_
+#define BRAVE_CHROMIUM_SRC_CHROME_COMMON_EXTENSIONS_PERMISSIONS_CHROME_PERMISSION_MESSAGE_RULES_H_
+
+#define GetAllRules           \
+  GetAllRules_ChromiumImpl(); \
+  static std::vector<ChromePermissionMessageRule> GetAllRules
+#include "../../../../../../chrome/common/extensions/permissions/chrome_permission_message_rules.h"
+#undef GetAllRules
+
+#endif  // BRAVE_CHROMIUM_SRC_CHROME_COMMON_EXTENSIONS_PERMISSIONS_CHROME_PERMISSION_MESSAGE_RULES_H_
diff --git a/chromium_src/extensions/common/permissions/api_permission.h b/chromium_src/extensions/common/permissions/api_permission.h
new file mode 100644
index 000000000000..55a2f06b7d4a
--- /dev/null
+++ b/chromium_src/extensions/common/permissions/api_permission.h
@@ -0,0 +1,15 @@
+/* Copyright (c) 2021 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at https://mozilla.org/MPL/2.0/. */
+
+#ifndef BRAVE_CHROMIUM_SRC_EXTENSIONS_COMMON_PERMISSIONS_API_PERMISSION_H_
+#define BRAVE_CHROMIUM_SRC_EXTENSIONS_COMMON_PERMISSIONS_API_PERMISSION_H_
+
+#define BRAVE_PERMISSION_IDS kIpfs = 750,
+
+#include "../../../../extensions/common/permissions/api_permission.h"
+
+#undef BRAVE_PERMISSION_IDS
+
+#endif  // BRAVE_CHROMIUM_SRC_EXTENSIONS_COMMON_PERMISSIONS_API_PERMISSION_H_
diff --git a/common/extensions/api/_ipfs_api_features.json b/common/extensions/api/_ipfs_api_features.json
index 2c7dbfae3833..b1aaec7677f1 100644
--- a/common/extensions/api/_ipfs_api_features.json
+++ b/common/extensions/api/_ipfs_api_features.json
@@ -18,5 +18,35 @@
     "channel": "stable",
     "contexts": ["blessed_extension"],
     "allowlist": ["780BF954C0F7C586EA9662D4F967771F49CC2114", "FF32507DC3DB5DFFD1D6733187C84D4B74713D63", "A321D47A2B4CA86898167A55CA8B2E02385EA7CD"]
+  }],
+  "ipfs.resolveIPFSURI": [{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": ["permission:ipfs"]
+  },{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": [],
+    "allowlist": ["780BF954C0F7C586EA9662D4F967771F49CC2114", "FF32507DC3DB5DFFD1D6733187C84D4B74713D63", "A321D47A2B4CA86898167A55CA8B2E02385EA7CD"]
+  }],
+  "ipfs.getIPFSEnabled": [{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": ["permission:ipfs"]
+  },{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": [],
+    "allowlist": ["780BF954C0F7C586EA9662D4F967771F49CC2114", "FF32507DC3DB5DFFD1D6733187C84D4B74713D63", "A321D47A2B4CA86898167A55CA8B2E02385EA7CD"]
+  }],
+  "ipfs.getResolveMethodType": [{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": ["permission:ipfs"]
+  },{
+    "channel": "stable",
+    "contexts": ["blessed_extension"],
+    "dependencies": [],
+    "allowlist": ["780BF954C0F7C586EA9662D4F967771F49CC2114", "FF32507DC3DB5DFFD1D6733187C84D4B74713D63", "A321D47A2B4CA86898167A55CA8B2E02385EA7CD"]
   }]
 }
diff --git a/common/extensions/api/_permission_features.json b/common/extensions/api/_permission_features.json
index 0f3756a2a5e5..3549e110caba 100644
--- a/common/extensions/api/_permission_features.json
+++ b/common/extensions/api/_permission_features.json
@@ -20,5 +20,9 @@
       "226CF815E39A363090A1E547D53063472B8279FA",  // Media Router Release
       "A321D47A2B4CA86898167A55CA8B2E02385EA7CD"   // Brave Shields
     ]
-  }]
+  }],
+  "ipfs": {
+    "channel": "stable",
+    "extension_types": ["extension"]
+  }
 }
diff --git a/patches/extensions-common-permissions-api_permission.h.patch b/patches/extensions-common-permissions-api_permission.h.patch
new file mode 100644
index 000000000000..fbdac904bc9b
--- /dev/null
+++ b/patches/extensions-common-permissions-api_permission.h.patch
@@ -0,0 +1,12 @@
+diff --git a/extensions/common/permissions/api_permission.h b/extensions/common/permissions/api_permission.h
+index 886adb61d224a1db57f38844748ddcf163840b18..2f6d333899b6cc49206de56ef4562a8b5c8d958a 100644
+--- a/extensions/common/permissions/api_permission.h
++++ b/extensions/common/permissions/api_permission.h
+@@ -272,6 +272,7 @@ class APIPermission {
+     kSearch = 228,
+     kTabGroups = 229,
+     kScripting = 230,
++    BRAVE_PERMISSION_IDS
+     // Last entry: Add new entries above and ensure to update the
+     // "ExtensionPermission3" enum in tools/metrics/histograms/enums.xml
+     // (by running update_extension_permission.py).