diff --git a/src/components/tooltip/tooltip-body.ts b/src/components/tooltip/tooltip-body.ts
index a30d68a71..a949bd153 100644
--- a/src/components/tooltip/tooltip-body.ts
+++ b/src/components/tooltip/tooltip-body.ts
@@ -1,7 +1,7 @@
 /**
  * @license
  *
- * Copyright IBM Corp. 2019, 2020
+ * Copyright IBM Corp. 2019, 2022
  *
  * This source code is licensed under the Apache-2.0 license found in the
  * LICENSE file in the root directory of this source tree.
@@ -9,6 +9,7 @@
 
 import settings from 'carbon-components/es/globals/js/settings';
 import { html, property, customElement } from 'lit-element';
+import HostListener from '../../globals/decorators/host-listener';
 import BXFloatingMenu, {
   FLOATING_MENU_ALIGNMENT,
   FLOATING_MENU_DIRECTION,
@@ -41,6 +42,17 @@ class BXTooltipBody extends BXFloatingMenu {
   @property({ type: Boolean, reflect: true })
   open = false;
 
+  /**
+   * Handles `keydown` event on this element.
+   */
+  @HostListener('keydown')
+  // @ts-ignore: The decorator refers to this method but TS thinks this method is not referred to
+  private _handleKeydown = async event => {
+    if (event.key === 'Escape') {
+      this.open = false;
+    }
+  };
+
   /**
    * The position of this tooltip body.
    */