diff --git a/Dockerfile b/Dockerfile
index dc71d699e..93924b1dd 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -86,28 +86,15 @@ RUN apt-get install -q -y zlib1g-dev libncurses5-dev libncursesw5-dev && \
 ## Install dependencies for genetracks/drawsvg
 RUN apt-get install -q -y libcairo2-dev
 
-COPY pyproject.toml /opt/micall/
+COPY . /opt/micall/
 
-## Python packages, plus trigger matplotlib to build its font cache
-WORKDIR /opt
-RUN pip install --upgrade pip && \
-  pip install .[basespace] && \
-  python -c 'import matplotlib; matplotlib.use("Agg"); import matplotlib.pyplot'
+RUN pip install --upgrade pip
+RUN pip install /opt/micall
+RUN micall make_blast_db
 
-## MiCall
-COPY micall_docker.py micall_kive.py micall_kive_resistance.py version.tx[t] /opt/micall/
-COPY micall/__init__.py micall/project* /opt/micall/micall/
-
-COPY micall/blast_db/make_blast_db.py    /opt/micall/micall/blast_db/make_blast_db.py
-COPY micall/core    /opt/micall/micall/core/
-COPY micall/data    /opt/micall/micall/data/
-COPY micall/drivers    /opt/micall/micall/drivers/
-COPY micall/g2p     /opt/micall/micall/g2p/
-COPY micall/resistance   /opt/micall/micall/resistance/
-COPY micall/monitor /opt/micall/micall/monitor/
-COPY micall/utils   /opt/micall/micall/utils/
-
-RUN python /opt/micall/micall/blast_db/make_blast_db.py
+## Trigger matplotlib to build its font cache
+RUN pip install .[basespace]
+RUN python -c 'import matplotlib; matplotlib.use("Agg"); import matplotlib.pyplot'
 
 WORKDIR /data
-ENTRYPOINT ["python", "/opt/micall/micall_docker.py"]
+ENTRYPOINT ["micall", "micall_docker"]