diff --git a/dandiapi/settings.py b/dandiapi/settings.py
index 464618fd5..7ed9df4b7 100644
--- a/dandiapi/settings.py
+++ b/dandiapi/settings.py
@@ -188,6 +188,9 @@ def mutate_configuration(configuration: type[ComposedConfiguration]):
         configuration.INSTALLED_APPS.remove('composed_configuration.sentry.apps.SentryConfig')
 
         # In production, enable rate limiting for unauthenticated users
+        configuration.REST_FRAMEWORK['DEFAULT_THROTTLE_CLASSES'] = [
+            'rest_framework.throttling.AnonRateThrottle',
+        ]
         configuration.REST_FRAMEWORK['DEFAULT_THROTTLE_RATES'] = {
             'anon': '300/minute',
         }