diff --git a/eng/native/configurecompiler.cmake b/eng/native/configurecompiler.cmake
index 0be4937c7f8d4..70685a048aea0 100644
--- a/eng/native/configurecompiler.cmake
+++ b/eng/native/configurecompiler.cmake
@@ -56,6 +56,9 @@ add_compile_definitions("$<$<OR:$<CONFIG:RELEASE>,$<CONFIG:RELWITHDEBINFO>>:NDEB
 if (MSVC)
   add_linker_flag(/guard:cf)
 
+  # Load all imported DLLs from the System32 directory.
+  add_linker_flag(/DEPENDENTLOADFLAG:0x800)
+
   # Linker flags
   #
   set (WINDOWS_SUBSYSTEM_VERSION 6.01)
diff --git a/eng/native/ijw/IJW.cmake b/eng/native/ijw/IJW.cmake
index 9ef90525dda8b..7ca232ee4b8e7 100644
--- a/eng/native/ijw/IJW.cmake
+++ b/eng/native/ijw/IJW.cmake
@@ -70,6 +70,10 @@ if (CLR_CMAKE_HOST_WIN32)
   remove_ijw_incompatible_options("${dirCompileOptions}" dirCompileOptions)
   set_directory_properties(PROPERTIES COMPILE_OPTIONS "${dirCompileOptions}")
 
+  # IJW tests needs to load DLLs from somewhere other than System32
+  string(REPLACE "/DEPENDENTLOADFLAG:0x800" "" CMAKE_EXE_LINKER_FLAGS "${CMAKE_EXE_LINKER_FLAGS}")
+  string(REPLACE "/DEPENDENTLOADFLAG:0x800" "" CMAKE_SHARED_LINKER_FLAGS "${CMAKE_SHARED_LINKER_FLAGS}")
+
   set(CLR_SDK_REF_PACK_OUTPUT "")
   set(CLR_SDK_REF_PACK_DISCOVERY_ERROR "")
   set(CLR_SDK_REF_PACK_DISCOVERY_RESULT 0)
diff --git a/src/coreclr/build-runtime.cmd b/src/coreclr/build-runtime.cmd
index ec6887c78d84c..7e85e50f9de4d 100644
--- a/src/coreclr/build-runtime.cmd
+++ b/src/coreclr/build-runtime.cmd
@@ -428,6 +428,10 @@ if %__BuildNative% EQU 1 (
         goto ExitWithCode
     )
 
+    @REM Temporarily disabling PGO until updated files with new linker flag are available.
+    @REM https://github.com/dotnet/runtime/pull/89311
+    GOTO :SkipNativeBuild
+
     if %__EnforcePgo% EQU 1 (
         set PgoCheckCmd="!PYTHON!" "!__ProjectDir!\scripts\pgocheck.py" "!__BinDir!\coreclr.dll" "!__BinDir!\clrjit.dll"
         echo !PgoCheckCmd!
diff --git a/src/coreclr/pgosupport.cmake b/src/coreclr/pgosupport.cmake
index 719ac14ad990b..a0a2b2ab305dd 100644
--- a/src/coreclr/pgosupport.cmake
+++ b/src/coreclr/pgosupport.cmake
@@ -59,9 +59,11 @@ function(add_pgo TargetName)
             message("Cannot use PGO optimization built with Ninja from MSBuild. Re-run build with Ninja to apply PGO information")
         else(NOT EXISTS ${ProfilePath})
             if(CLR_CMAKE_HOST_WIN32)
-                set_property(TARGET ${TargetName} APPEND_STRING PROPERTY LINK_FLAGS_RELEASE        " /LTCG /USEPROFILE:PGD=\"${ProfilePath}\"")
-                set_property(TARGET ${TargetName} APPEND_STRING PROPERTY LINK_FLAGS_RELWITHDEBINFO " /LTCG /USEPROFILE:PGD=\"${ProfilePath}\"")
-                add_compile_definitions(WITH_NATIVE_PGO)
+                # Temporarily disabling PGO until updated files with new linker flag are available.
+                # https://github.com/dotnet/runtime/pull/89311
+                # set_property(TARGET ${TargetName} APPEND_STRING PROPERTY LINK_FLAGS_RELEASE        " /LTCG /USEPROFILE:PGD=\"${ProfilePath}\"")
+                # set_property(TARGET ${TargetName} APPEND_STRING PROPERTY LINK_FLAGS_RELWITHDEBINFO " /LTCG /USEPROFILE:PGD=\"${ProfilePath}\"")
+                # add_compile_definitions(WITH_NATIVE_PGO)
             else(CLR_CMAKE_HOST_WIN32)
                 if(UPPERCASE_CMAKE_BUILD_TYPE STREQUAL RELEASE OR UPPERCASE_CMAKE_BUILD_TYPE STREQUAL RELWITHDEBINFO)
                     if((CMAKE_CXX_COMPILER_ID MATCHES "Clang") AND (NOT CMAKE_CXX_COMPILER_VERSION VERSION_LESS 16))