diff --git a/eng/Subsets.props b/eng/Subsets.props
index 692812a9f7651..140299508e6a4 100644
--- a/eng/Subsets.props
+++ b/eng/Subsets.props
@@ -45,7 +45,7 @@
     <DefaultMonoSubsets Condition="'$(MonoEnableLLVM)' == 'true' and '$(MonoLLVMDir)' == ''">mono.llvm+</DefaultMonoSubsets>
     <DefaultMonoSubsets Condition="'$(MonoAOTEnableLLVM)' == 'true' and '$(MonoAOTLLVMDir)' == ''">mono.llvm+</DefaultMonoSubsets>
     <DefaultMonoSubsets Condition="'$(TargetOS)' == 'Browser'">$(DefaultMonoSubsets)mono.wasmruntime+</DefaultMonoSubsets>
-    <DefaultMonoSubsets Condition="'$(BuildMonoCrossAOT)' == 'true'">$(DefaultMonoSubsets)mono.aotcross+</DefaultMonoSubsets>
+    <DefaultMonoSubsets Condition="'$(MonoCrossAOTTargetOS)' != ''">$(DefaultMonoSubsets)mono.aotcross+</DefaultMonoSubsets>
     <DefaultMonoSubsets>$(DefaultMonoSubsets)mono.runtime+mono.corelib+mono.packages</DefaultMonoSubsets>
 
     <DefaultLibrariesSubsets>libs.native+libs.ref+libs.src+libs.pretest+libs.packages</DefaultLibrariesSubsets>
@@ -288,7 +288,7 @@
     <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' != 'Mono'" Include="$(InstallerProjectRoot)pkg\sfx\installers\dotnet-hostfxr.proj" />
     <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' != 'Mono'" Include="$(InstallerProjectRoot)pkg\sfx\installers\dotnet-runtime-deps\*.proj" />
     <SharedFrameworkProjectToBuild Condition="'$(RuntimeFlavor)' != 'Mono'" Include="$(InstallerProjectRoot)pkg\sfx\bundle\Microsoft.NETCore.App.Bundle.bundleproj" />
-    <SharedFrameworkProjectToBuild Condition="'$(BuildMonoCrossAOT)' == 'true'" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\monocrossaot.sfxproj" />
+    <SharedFrameworkProjectToBuild Condition="'$(MonoCrossAOTTargetOS)' != ''" Include="$(InstallerProjectRoot)pkg\sfx\Microsoft.NETCore.App\monocrossaot.sfxproj" />
     <ProjectToBuild Include="@(SharedFrameworkProjectToBuild)" Category="packs" />
   </ItemGroup>
 
diff --git a/eng/pipelines/common/global-build-job.yml b/eng/pipelines/common/global-build-job.yml
index 586e9df6d7bcd..d006c2cf29e14 100644
--- a/eng/pipelines/common/global-build-job.yml
+++ b/eng/pipelines/common/global-build-job.yml
@@ -11,7 +11,7 @@ parameters:
   variables: []
   targetRid: ''
   timeoutInMinutes: ''
-  dependsOn: ''
+  dependsOn: []
   pool: ''
   platform: ''
   condition: true
@@ -89,11 +89,11 @@ jobs:
     - ${{ if eq(parameters.isOfficialBuild, true) }}:
       - template: /eng/pipelines/common/restore-internal-tools.yml
 
-    - ${{ if eq(parameters.monoCrossAOTTargetOS, 'Android') }}:
+    - ${{ each monoCrossAOTTargetOS in parameters.monoCrossAOTTargetOS }}:
       - task: DownloadPipelineArtifact@2
-        displayName: Download AOT offset files
+        displayName: Download ${{monoCrossAOTTargetOS}} AOT offset files
         inputs:
-          artifact: Mono_Offsets_Android
+          artifact: Mono_Offsets_${{monoCrossAOTTargetOS}}
           path: '$(Build.SourcesDirectory)/artifacts/obj/mono/offsetfiles'
 
     - ${{ if in(parameters.osGroup, 'OSX', 'iOS', 'tvOS', 'Android') }}:
diff --git a/eng/pipelines/mono/templates/build-job.yml b/eng/pipelines/mono/templates/build-job.yml
index 1b7c3d9abd8da..48b18b1c8b50c 100644
--- a/eng/pipelines/mono/templates/build-job.yml
+++ b/eng/pipelines/mono/templates/build-job.yml
@@ -13,8 +13,8 @@ parameters:
   isOfficialBuild: false
   crossBuild: false
   crossrootfsDir: ''
-  dependsOn: ''
-  monoCrossAOTTargetOS: ''
+  dependsOn: []
+  monoCrossAOTTargetOS: []
   dependOnEvaluatePaths: false
 
 ### Product build
@@ -93,9 +93,9 @@ jobs:
     - ${{ if eq(parameters.runtimeVariant, 'llvmaot') }}:
       - name: llvmParameter
         value: /p:MonoEnableLLVM=true /p:MonoBundleLLVMOptimizer=true $(llvmCxxAbi)
-    - ${{ if eq(parameters.monoCrossAOTTargetOS, 'Android') }}:
+    - ${{ if gt(length(parameters.monoCrossAOTTargetOS),0) }}:
       - name: aotCrossParameter
-        value: /p:BuildMonoCrossAOT=true /p:SkipMonoCrossJitConfigure=true /p:BuildMonoAOTCrossCompilerOnly=true
+        value: /p:MonoCrossAOTTargetOS=${{join('+',parameters.monoCrossAOTTargetOS)}} /p:SkipMonoCrossJitConfigure=true /p:BuildMonoAOTCrossCompilerOnly=true
     - ${{ parameters.variables }}
 
     steps:
@@ -112,11 +112,11 @@ jobs:
       - script: $(Build.SourcesDirectory)\eng\common\init-tools-native.cmd -InstallDirectory $(Build.SourcesDirectory)\native-tools -Force
         displayName: Install native dependencies
 
-    - ${{ if eq(parameters.monoCrossAOTTargetOS, 'Android') }}:
+    - ${{ each monoCrossAOTTargetOS in parameters.monoCrossAOTTargetOS }}:
       - task: DownloadPipelineArtifact@2
-        displayName: Download AOT offset files
+        displayName: Download ${{monoCrossAOTTargetOS}} AOT offset files
         inputs:
-          artifact: Mono_Offsets_Android
+          artifact: Mono_Offsets_${{monoCrossAOTTargetOS}}
           path: '$(Build.SourcesDirectory)/artifacts/obj/mono/offsetfiles'
 
     - ${{ if in(parameters.osGroup, 'OSX', 'iOS','tvOS') }}:
diff --git a/eng/pipelines/mono/templates/generate-offsets.yml b/eng/pipelines/mono/templates/generate-offsets.yml
index 7b3117706ef5a..ff3b3e9d70ca7 100644
--- a/eng/pipelines/mono/templates/generate-offsets.yml
+++ b/eng/pipelines/mono/templates/generate-offsets.yml
@@ -62,10 +62,10 @@ jobs:
 
     # Build
     - ${{ if ne(parameters.osGroup, 'windows') }}:
-      - script: ./build$(scriptExt) -subset mono.aotcross -c $(buildConfig) -arch $(archType) $(osOverride) -ci $(officialBuildIdArg) /p:MonoGenerateOffsetsOnly=true
+      - script: ./build$(scriptExt) -subset mono.aotcross -c $(buildConfig) -arch $(archType) $(osOverride) -ci $(officialBuildIdArg) /p:MonoGenerateOffsetsOSGroups=$(osGroup)
         displayName: Generate AOT offsets
     - ${{ if eq(parameters.osGroup, 'windows') }}:
-      - script: build$(scriptExt) -subset mono.aotcross -c $(buildConfig) -arch $(archType) $(osOverride) -ci $(officialBuildIdArg) /p:MonoGenerateOffsetsOnly=true
+      - script: build$(scriptExt) -subset mono.aotcross -c $(buildConfig) -arch $(archType) $(osOverride) -ci $(officialBuildIdArg) /p:MonoGenerateOffsetsOSGroups=$(osGroup)
         displayName: Generate AOT offsets
 
     # Upload offset files
diff --git a/eng/pipelines/runtime-official.yml b/eng/pipelines/runtime-official.yml
index 2bab2f0bfcf87..4dd467fe931e7 100644
--- a/eng/pipelines/runtime-official.yml
+++ b/eng/pipelines/runtime-official.yml
@@ -132,9 +132,10 @@ stages:
       buildConfig: release
       platforms:
       - Android_x64
+      - Browser_wasm
 
   #
-  # Build Mono release Android AOT cross-compiler
+  # Build Mono release AOT cross-compilers
   #
   - template: /eng/pipelines/common/platform-matrix.yml
     parameters:
@@ -146,15 +147,20 @@ stages:
       - Linux_x64
       jobParameters:
         buildArgs: -s mono+libs+host+packs -c $(_BuildConfig)
-                   /p:BuildMonoCrossAOT=true /p:SkipMonoCrossJitConfigure=true /p:BuildMonoAOTCrossCompilerOnly=true
-        nameSuffix: AndroidAOT_Mono
-        runtimeVariant: crossandroid
-        dependsOn: mono_android_offsets
-        monoCrossAOTTargetOS: Android
+                   /p:MonoCrossAOTTargetOS=Android+Browser /p:SkipMonoCrossJitConfigure=true /p:BuildMonoAOTCrossCompilerOnly=true
+        nameSuffix: CrossAOT_Mono
+        runtimeVariant: crossaot
+        dependsOn:
+        - mono_android_offsets
+        - mono_browser_offsets
+        monoCrossAOTTargetOS:
+        - Android
+        - Browser
         isOfficialBuild: ${{ variables.isOfficialBuild }}
         extraStepsTemplate: /eng/pipelines/common/upload-intermediate-artifacts-step.yml
         extraStepsParameters:
           name: MonoRuntimePacks
+
   #
   # Build Mono LLVM runtime packs
   #
diff --git a/eng/pipelines/runtime.yml b/eng/pipelines/runtime.yml
index da9d540235a96..6984eecd6b69b 100644
--- a/eng/pipelines/runtime.yml
+++ b/eng/pipelines/runtime.yml
@@ -192,6 +192,7 @@ jobs:
     buildConfig: release
     platforms:
     - Android_x64
+    - Browser_wasm
     jobParameters:
       condition: >-
         or(
@@ -494,9 +495,13 @@ jobs:
     # - windows_arm
     # - windows_arm64
     jobParameters:
-      runtimeVariant: crossandroid
-      dependsOn: mono_android_offsets
-      monoCrossAOTTargetOS: Android
+      runtimeVariant: crossaot
+      dependsOn:
+      - mono_android_offsets
+      - mono_browser_offsets
+      monoCrossAOTTargetOS:
+      - Android
+      - Browser
       condition: >-
         or(
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
diff --git a/src/installer/pkg/sfx/Microsoft.NETCore.App/monocrossaot.sfxproj b/src/installer/pkg/sfx/Microsoft.NETCore.App/monocrossaot.sfxproj
index 97ff1a1de517a..0859d9debbea8 100644
--- a/src/installer/pkg/sfx/Microsoft.NETCore.App/monocrossaot.sfxproj
+++ b/src/installer/pkg/sfx/Microsoft.NETCore.App/monocrossaot.sfxproj
@@ -1,7 +1,9 @@
 <Project Sdk="Microsoft.Build.Traversal">
 
   <PropertyGroup>
-    <MonoAotTargets Condition="'$(MonoAotTargets)' == ''">android-x64;android-arm64;android-x86;android-arm</MonoAotTargets>
+    <_MonoCrossAOTTargetOS Condition="'$(MonoCrossAOTTargetOS)' != ''">+$(MonoCrossAOTTargetOS.ToLowerInvariant())+</_MonoCrossAOTTargetOS>
+    <MonoAotTargets Condition="$(_MonoCrossAOTTargetOS.contains('+android+'))">$(MonoAotTargets);android-x64;android-arm64;android-x86;android-arm</MonoAotTargets>
+    <MonoAotTargets Condition="$(_MonoCrossAOTTargetOS.contains('+wasm+'))">$(MonoAotTargets);browser-wasm</MonoAotTargets>
   </PropertyGroup>
 
   <ItemGroup>
diff --git a/src/mono/mono.proj b/src/mono/mono.proj
index 68a5d51a4bb31..a0b25a4e0cdec 100644
--- a/src/mono/mono.proj
+++ b/src/mono/mono.proj
@@ -74,7 +74,7 @@
     <Error Condition="'$(TargetsiOS)' == 'true' and '$(Platform)' != 'x64' and '$(Platform)' != 'x86' and '$(Platform)' != 'arm64' and '$(Platform)' != 'arm'" Text="Error: Invalid platform for $(TargetOS): $(Platform)." />
     <Error Condition="('$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true') and !$([MSBuild]::IsOSPlatform('OSX'))" Text="Error: $(TargetOS) can only be built on macOS." />
     <Error Condition="'$(TargetsAndroid)' == 'true' and '$(Platform)' != 'x64' and '$(Platform)' != 'x86' and '$(Platform)' != 'arm64' and '$(Platform)' != 'arm'" Text="Error: Invalid platform for $(TargetOS): $(Platform)." />
-    <Error Condition="'$(TargetsBrowser)' == 'true' and '$(EMSDK_PATH)' == ''" Text="The EMSDK_PATH environment variable should be set pointing to the emscripten SDK root dir."/>
+    <Error Condition="'$(TargetsBrowser)' == 'true' and '$(EMSDK_PATH)' == '' and '$(SkipMonoCrossJitConfigure)' != 'true'" Text="The EMSDK_PATH environment variable should be set pointing to the emscripten SDK root dir."/>
     <Error Condition="'$(TargetsAndroid)' == 'true' and '$(ANDROID_NDK_ROOT)' == '' and '$(SkipMonoCrossJitConfigure)' != 'true'" Text="Error: You need to set the ANDROID_NDK_ROOT environment variable pointing to the Android NDK root." />
     <Error Condition="'$(OS)' == 'Windows_NT' and ('$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true')" Text="Error: Mono runtime for $(TargetOS) can't be built on Windows." />
 
@@ -472,10 +472,10 @@
     <Exec Condition="'$(MonoUseCrossTool)' == 'true' and !Exists('$(MonoAotOffsetsFile)')" Command="$(_MonoAotCrossOffsetsCommand)" IgnoreStandardErrorWarningFormat="true" />
     <!-- configure -->
     <Message Text="Running '$(_MonoAotCMakeConfigureCommand)' in '$(MonoObjDir)/cross'" Importance="High" />
-    <Exec Condition="'$(MonoGenerateOffsetsOnly)' != 'true'" Command="$(_MonoAotCMakeConfigureCommand)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)/cross"/>
+    <Exec Condition="'$(MonoGenerateOffsetsOSGroups)' == ''" Command="$(_MonoAotCMakeConfigureCommand)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)/cross"/>
     <!-- build -->
     <Message Text="Running '$(_MonoAotCMakeBuildCommand)' in '$(MonoObjDir)/cross'" Importance="High" />
-    <Exec Condition="'$(MonoGenerateOffsetsOnly)' != 'true'" Command="$(_MonoAotCMakeBuildCommand)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)/cross"/>
+    <Exec Condition="'$(MonoGenerateOffsetsOSGroups)' == ''" Command="$(_MonoAotCMakeBuildCommand)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)/cross"/>
   </Target>
 
   <Target Name="InitializeGenerateRuntimeVersionFile"
@@ -543,22 +543,22 @@
       <_MonoRuntimeArtifacts Condition="'$(_MonoIncludeInterpStaticFiles)' == 'true'" Include="$(MonoObjDir)out\lib\libmono-ilgen.a">
         <Destination>$(RuntimeBinDir)libmono-ilgen.a</Destination>
       </_MonoRuntimeArtifacts>
-      <_MonoRuntimeArtifacts Condition="'$(TargetsBrowser)' == 'true'" Include="$(MonoObjDir)out\lib\libmono-profiler-aot.a">
+      <_MonoRuntimeArtifacts Condition="'$(TargetsBrowser)' == 'true' and '$(BuildMonoAOTCrossCompilerOnly)' != 'true'" Include="$(MonoObjDir)out\lib\libmono-profiler-aot.a">
         <Destination>$(RuntimeBinDir)libmono-profiler-aot.a</Destination>
       </_MonoRuntimeArtifacts>
     </ItemGroup>
 
     <Copy SourceFiles="@(_MonoRuntimeArtifacts)"
           DestinationFiles="%(_MonoRuntimeArtifacts.Destination)"
-          Condition="'$(MonoGenerateOffsetsOnly)' != 'true'"
+          Condition="'$(MonoGenerateOffsetsOSGroups)' == ''"
           SkipUnchangedFiles="true" />
 
     <Copy SourceFiles="@(_MonoIncludeArtifacts)"
           DestinationFiles="@(_MonoIncludeArtifacts->'$(RuntimeBinDir)include\%(RecursiveDir)%(Filename)%(Extension)')"
           SkipUnchangedFiles="true"
-          Condition="'$(MonoGenerateOffsetsOnly)' != 'true' and ('$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsAndroid)' == 'true' or '$(TargetsBrowser)' == 'true')"/>
+          Condition="'$(MonoGenerateOffsetsOSGroups)' == '' and ('$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsAndroid)' == 'true' or '$(TargetsBrowser)' == 'true')"/>
 
-    <Exec Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true' and '$(MonoGenerateOffsetsOnly)' != 'true' and ('$(TargetsOSX)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true')" Command="install_name_tool -id @rpath/$(MonoFileName) $(RuntimeBinDir)$(MonoFileName)" />
+    <Exec Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true' and '$(MonoGenerateOffsetsOSGroups)' == '' and ('$(TargetsOSX)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true')" Command="install_name_tool -id @rpath/$(MonoFileName) $(RuntimeBinDir)$(MonoFileName)" />
   </Target>
 
   <Target Name="CleanMono">
diff --git a/src/mono/monoaotcross.proj b/src/mono/monoaotcross.proj
index 99ad16a0655f7..260d5203ad55b 100644
--- a/src/mono/monoaotcross.proj
+++ b/src/mono/monoaotcross.proj
@@ -5,7 +5,12 @@
 
   <PropertyGroup>
     <!-- OS name is case sensitive! -->
-    <MonoAotTargets Condition="'$(MonoAotTargets)' == ''">Android-x64;Android-arm64;Android-x86;Android-arm</MonoAotTargets>
+    <_MonoCrossAOTTargetOS Condition="'$(MonoCrossAOTTargetOS)' != ''">+$(MonoCrossAOTTargetOS.ToLowerInvariant())+</_MonoCrossAOTTargetOS>
+    <_MonoGenerateOffsetsOSGroups Condition="'$(MonoGenerateOffsetsOSGroups)' != ''">+$(MonoGenerateOffsetsOSGroups.ToLowerInvariant())+</_MonoGenerateOffsetsOSGroups>
+    <_MonoCrossAOTTargetOS Condition="$(_MonoGenerateOffsetsOSGroups.contains('+android+'))">$(_MonoCrossAOTTargetOS)+android+</_MonoCrossAOTTargetOS>
+    <_MonoCrossAOTTargetOS Condition="$(_MonoGenerateOffsetsOSGroups.contains('+browser+'))">$(_MonoCrossAOTTargetOS)+browser+</_MonoCrossAOTTargetOS>
+    <MonoAotTargets Condition="$(_MonoCrossAOTTargetOS.contains('+android+'))">$(MonoAotTargets);Android-x64;Android-arm64;Android-x86;Android-arm</MonoAotTargets>
+    <MonoAotTargets Condition="$(_MonoCrossAOTTargetOS.contains('+browser+'))">$(MonoAotTargets);Browser-wasm</MonoAotTargets>
   </PropertyGroup>
 
   <ItemGroup>