diff --git a/packages/react-is/README.md b/packages/react-is/README.md
index d255977618178..c446e89c6b0fe 100644
--- a/packages/react-is/README.md
+++ b/packages/react-is/README.md
@@ -40,7 +40,6 @@ ReactIs.isValidElementType(FunctionComponent); // true
 ReactIs.isValidElementType(ForwardRefComponent); // true
 ReactIs.isValidElementType(Context.Provider); // true
 ReactIs.isValidElementType(Context.Consumer); // true
-ReactIs.isValidElementType(React.createFactory("div")); // true
 ```
 
 ### Determining an Element's Type
diff --git a/packages/react-is/src/__tests__/ReactIs-test.js b/packages/react-is/src/__tests__/ReactIs-test.js
index 5b63eebd529fd..f9d9dc923cc23 100644
--- a/packages/react-is/src/__tests__/ReactIs-test.js
+++ b/packages/react-is/src/__tests__/ReactIs-test.js
@@ -67,18 +67,6 @@ describe('ReactIs', () => {
     expect(ReactIs.isValidElementType(MemoComponent)).toEqual(true);
     expect(ReactIs.isValidElementType(Context.Provider)).toEqual(true);
     expect(ReactIs.isValidElementType(Context.Consumer)).toEqual(true);
-    if (!__EXPERIMENTAL__) {
-      let factory;
-      expect(() => {
-        factory = React.createFactory('div');
-      }).toWarnDev(
-        'Warning: React.createFactory() is deprecated and will be removed in a ' +
-          'future major release. Consider using JSX or use React.createElement() ' +
-          'directly instead.',
-        {withoutStack: true},
-      );
-      expect(ReactIs.isValidElementType(factory)).toEqual(true);
-    }
     expect(ReactIs.isValidElementType(React.Fragment)).toEqual(true);
     expect(ReactIs.isValidElementType(React.StrictMode)).toEqual(true);
     expect(ReactIs.isValidElementType(React.Suspense)).toEqual(true);
diff --git a/packages/react/src/React.js b/packages/react/src/React.js
index 5728a2ba50d78..e1b42d64bc81f 100644
--- a/packages/react/src/React.js
+++ b/packages/react/src/React.js
@@ -27,7 +27,6 @@ import {createRef} from './ReactCreateRef';
 import {forEach, map, count, toArray, only} from './ReactChildren';
 import {
   createElement as createElementProd,
-  createFactory as createFactoryProd,
   cloneElement as cloneElementProd,
   isValidElement,
 } from './ReactElement';
@@ -63,7 +62,6 @@ import {
 } from './ReactHooks';
 import {
   createElementWithValidation,
-  createFactoryWithValidation,
   cloneElementWithValidation,
 } from './ReactElementValidator';
 import {createServerContext} from './ReactServerContext';
@@ -78,9 +76,6 @@ const createElement: any = __DEV__
 const cloneElement: any = __DEV__
   ? cloneElementWithValidation
   : cloneElementProd;
-const createFactory: any = __DEV__
-  ? createFactoryWithValidation
-  : createFactoryProd;
 
 const Children = {
   map,
@@ -126,8 +121,6 @@ export {
   isValidElement,
   ReactVersion as version,
   ReactSharedInternals as __SECRET_INTERNALS_DO_NOT_USE_OR_YOU_WILL_BE_FIRED,
-  // Deprecated behind disableCreateFactory
-  createFactory,
   // Concurrent Mode
   useTransition,
   startTransition,
diff --git a/packages/react/src/ReactElement.js b/packages/react/src/ReactElement.js
index e9d721b92693a..af2a6d4fd8a25 100644
--- a/packages/react/src/ReactElement.js
+++ b/packages/react/src/ReactElement.js
@@ -450,21 +450,6 @@ export function createElement(type, config, children) {
   );
 }
 
-/**
- * Return a function that produces ReactElements of a given type.
- * See https://reactjs.org/docs/react-api.html#createfactory
- */
-export function createFactory(type) {
-  const factory = createElement.bind(null, type);
-  // Expose the type on the factory and the prototype so that it can be
-  // easily accessed on elements. E.g. `<Foo />.type === Foo`.
-  // This should not be named `constructor` since this may not be the function
-  // that created the element, and it may not even be a constructor.
-  // Legacy hook: remove it
-  factory.type = type;
-  return factory;
-}
-
 export function cloneAndReplaceKey(oldElement, newKey) {
   const newElement = ReactElement(
     oldElement.type,
diff --git a/packages/react/src/ReactElementValidator.js b/packages/react/src/ReactElementValidator.js
index 8281057750e9c..ddca597b2bbc1 100644
--- a/packages/react/src/ReactElementValidator.js
+++ b/packages/react/src/ReactElementValidator.js
@@ -508,39 +508,6 @@ export function createElementWithValidation(type, props, children) {
   return element;
 }
 
-let didWarnAboutDeprecatedCreateFactory = false;
-
-export function createFactoryWithValidation(type) {
-  const validatedFactory = createElementWithValidation.bind(null, type);
-  validatedFactory.type = type;
-  if (__DEV__) {
-    if (!didWarnAboutDeprecatedCreateFactory) {
-      didWarnAboutDeprecatedCreateFactory = true;
-      console.warn(
-        'React.createFactory() is deprecated and will be removed in ' +
-          'a future major release. Consider using JSX ' +
-          'or use React.createElement() directly instead.',
-      );
-    }
-    // Legacy hook: remove it
-    Object.defineProperty(validatedFactory, 'type', {
-      enumerable: false,
-      get: function () {
-        console.warn(
-          'Factory.type is deprecated. Access the class directly ' +
-            'before passing it to createFactory.',
-        );
-        Object.defineProperty(this, 'type', {
-          value: type,
-        });
-        return type;
-      },
-    });
-  }
-
-  return validatedFactory;
-}
-
 export function cloneElementWithValidation(element, props, children) {
   const newElement = cloneElement.apply(this, arguments);
   for (let i = 2; i < arguments.length; i++) {
diff --git a/packages/react/src/__tests__/ReactElementValidator-test.internal.js b/packages/react/src/__tests__/ReactElementValidator-test.internal.js
index c447f554a71ac..5b90aab54ae5a 100644
--- a/packages/react/src/__tests__/ReactElementValidator-test.internal.js
+++ b/packages/react/src/__tests__/ReactElementValidator-test.internal.js
@@ -438,34 +438,6 @@ describe('ReactElementValidator', () => {
     );
   });
 
-  if (!__EXPERIMENTAL__) {
-    it('should warn when accessing .type on an element factory', () => {
-      function TestComponent() {
-        return <div />;
-      }
-
-      let TestFactory;
-
-      expect(() => {
-        TestFactory = React.createFactory(TestComponent);
-      }).toWarnDev(
-        'Warning: React.createFactory() is deprecated and will be removed in a ' +
-          'future major release. Consider using JSX or use React.createElement() ' +
-          'directly instead.',
-        {withoutStack: true},
-      );
-
-      expect(() => TestFactory.type).toWarnDev(
-        'Warning: Factory.type is deprecated. Access the class directly before ' +
-          'passing it to createFactory.',
-        {withoutStack: true},
-      );
-
-      // Warn once, not again
-      expect(TestFactory.type).toBe(TestComponent);
-    });
-  }
-
   it('does not warn when using DOM node as children', () => {
     class DOMContainer extends React.Component {
       render() {