diff --git a/compiler/packages/babel-plugin-react-compiler/src/Entrypoint/Pipeline.ts b/compiler/packages/babel-plugin-react-compiler/src/Entrypoint/Pipeline.ts
index 6d231919a6693..97ec36626b67b 100644
--- a/compiler/packages/babel-plugin-react-compiler/src/Entrypoint/Pipeline.ts
+++ b/compiler/packages/babel-plugin-react-compiler/src/Entrypoint/Pipeline.ts
@@ -70,7 +70,9 @@ import {
 } from "../ReactiveScopes";
 import { alignMethodCallScopes } from "../ReactiveScopes/AlignMethodCallScopes";
 import { alignReactiveScopesToBlockScopesHIR } from "../ReactiveScopes/AlignReactiveScopesToBlockScopesHIR";
+import { flattenReactiveLoopsHIR } from "../ReactiveScopes/FlattenReactiveLoopsHIR";
 import { pruneAlwaysInvalidatingScopes } from "../ReactiveScopes/PruneAlwaysInvalidatingScopes";
+import pruneInitializationDependencies from "../ReactiveScopes/PruneInitializationDependencies";
 import { stabilizeBlockIds } from "../ReactiveScopes/StabilizeBlockIds";
 import { eliminateRedundantPhi, enterSSA, leaveSSA } from "../SSA";
 import { inferTypes } from "../TypeInference";
@@ -91,7 +93,6 @@ import {
   validatePreservedManualMemoization,
   validateUseMemo,
 } from "../Validation";
-import pruneInitializationDependencies from "../ReactiveScopes/PruneInitializationDependencies";
 
 export type CompilerPipelineValue =
   | { kind: "ast"; name: string; value: CodegenFunction }
@@ -281,6 +282,13 @@ function* runWithEnvironment(
     });
 
     assertValidBlockNesting(hir);
+
+    flattenReactiveLoopsHIR(hir);
+    yield log({
+      kind: "hir",
+      name: "FlattenReactiveLoopsHIR",
+      value: hir,
+    });
   }
 
   const reactiveFunction = buildReactiveFunction(hir);
@@ -320,14 +328,14 @@ function* runWithEnvironment(
       name: "BuildReactiveBlocks",
       value: reactiveFunction,
     });
-  }
 
-  flattenReactiveLoops(reactiveFunction);
-  yield log({
-    kind: "reactive",
-    name: "FlattenReactiveLoops",
-    value: reactiveFunction,
-  });
+    flattenReactiveLoops(reactiveFunction);
+    yield log({
+      kind: "reactive",
+      name: "FlattenReactiveLoops",
+      value: reactiveFunction,
+    });
+  }
 
   assertScopeInstructionsWithinScopes(reactiveFunction);
 
diff --git a/compiler/packages/babel-plugin-react-compiler/src/ReactiveScopes/FlattenReactiveLoopsHIR.ts b/compiler/packages/babel-plugin-react-compiler/src/ReactiveScopes/FlattenReactiveLoopsHIR.ts
new file mode 100644
index 0000000000000..6fa65ee2bf257
--- /dev/null
+++ b/compiler/packages/babel-plugin-react-compiler/src/ReactiveScopes/FlattenReactiveLoopsHIR.ts
@@ -0,0 +1,71 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ */
+
+import { BlockId, HIRFunction, PrunedScopeTerminal } from "../HIR";
+import { assertExhaustive, retainWhere } from "../Utils/utils";
+
+/**
+ * Prunes any reactive scopes that are within a loop (for, while, etc). We don't yet
+ * support memoization within loops because this would require an extra layer of reconciliation
+ * (plus a way to identify values across runs, similar to how we use `key` in JSX for lists).
+ * Eventually we may integrate more deeply into the runtime so that we can do a single level
+ * of reconciliation, but for now we've found it's sufficient to memoize *around* the loop.
+ */
+export function flattenReactiveLoopsHIR(fn: HIRFunction): void {
+  const activeLoops = Array<BlockId>();
+  for (const [, block] of fn.body.blocks) {
+    retainWhere(activeLoops, (id) => id !== block.id);
+    const { terminal } = block;
+    switch (terminal.kind) {
+      case "do-while":
+      case "for":
+      case "for-in":
+      case "for-of":
+      case "while": {
+        activeLoops.push(terminal.fallthrough);
+        break;
+      }
+      case "scope": {
+        if (activeLoops.length !== 0) {
+          block.terminal = {
+            kind: "pruned-scope",
+            block: terminal.block,
+            fallthrough: terminal.fallthrough,
+            id: terminal.id,
+            loc: terminal.loc,
+            scope: terminal.scope,
+          } as PrunedScopeTerminal;
+        }
+        break;
+      }
+      case "branch":
+      case "goto":
+      case "if":
+      case "label":
+      case "logical":
+      case "maybe-throw":
+      case "optional":
+      case "pruned-scope":
+      case "return":
+      case "sequence":
+      case "switch":
+      case "ternary":
+      case "throw":
+      case "try":
+      case "unreachable":
+      case "unsupported": {
+        break;
+      }
+      default: {
+        assertExhaustive(
+          terminal,
+          `Unexpected terminal kind \`${(terminal as any).kind}\``
+        );
+      }
+    }
+  }
+}