diff --git a/src/common.ts b/src/common.ts
index edee0efd..de944c7c 100644
--- a/src/common.ts
+++ b/src/common.ts
@@ -14,8 +14,16 @@
 import {Agent} from 'http';
 import {URL} from 'url';
 
-/* eslint-disable @typescript-eslint/no-explicit-any */
+import {pkg} from './util';
 
+/**
+ * Support `instanceof` operator for `GaxiosError`s in different versions of this library.
+ *
+ * @see {@link GaxiosError[Symbol.hasInstance]}
+ */
+export const GAXIOS_ERROR_SYMBOL = Symbol.for(`${pkg.name}-gaxios-error`);
+
+/* eslint-disable-next-line @typescript-eslint/no-explicit-any */
 export class GaxiosError<T = any> extends Error {
   /**
    * An Error code.
@@ -34,6 +42,37 @@ export class GaxiosError<T = any> extends Error {
    */
   status?: number;
 
+  /**
+   * Support `instanceof` operator for `GaxiosError` across builds/duplicated files.
+   *
+   * @see {@link GAXIOS_ERROR_SYMBOL}
+   * @see {@link GaxiosError[Symbol.hasInstance]}
+   * @see {@link https://github.com/microsoft/TypeScript/issues/13965#issuecomment-278570200}
+   * @see {@link https://stackoverflow.com/questions/46618852/require-and-instanceof}
+   * @see {@link https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/Function/@@hasInstance#reverting_to_default_instanceof_behavior}
+   */
+  [GAXIOS_ERROR_SYMBOL] = pkg.version;
+
+  /**
+   * Support `instanceof` operator for `GaxiosError` across builds/duplicated files.
+   *
+   * @see {@link GAXIOS_ERROR_SYMBOL}
+   * @see {@link GaxiosError[GAXIOS_ERROR_SYMBOL]}
+   */
+  static [Symbol.hasInstance](instance: unknown) {
+    if (
+      instance &&
+      typeof instance === 'object' &&
+      GAXIOS_ERROR_SYMBOL in instance &&
+      instance[GAXIOS_ERROR_SYMBOL] === pkg.version
+    ) {
+      return true;
+    }
+
+    // fallback to native
+    return Function.prototype[Symbol.hasInstance].call(GaxiosError, instance);
+  }
+
   constructor(
     message: string,
     public config: GaxiosOptions,
diff --git a/src/util.ts b/src/util.ts
new file mode 100644
index 00000000..1428c3bc
--- /dev/null
+++ b/src/util.ts
@@ -0,0 +1,17 @@
+// Copyright 2023 Google LLC
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//    http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+export const pkg: {
+  name: string;
+  version: string;
+} = require('../../package.json');
diff --git a/test/test.getch.ts b/test/test.getch.ts
index 844cba04..f61eeea8 100644
--- a/test/test.getch.ts
+++ b/test/test.getch.ts
@@ -26,6 +26,8 @@ import {
   GaxiosResponse,
   GaxiosPromise,
 } from '../src';
+import {GAXIOS_ERROR_SYMBOL} from '../src/common';
+import {pkg} from '../src/util';
 import qs from 'querystring';
 import fs from 'fs';
 import {Blob} from 'node-fetch';
@@ -119,6 +121,18 @@ describe('🚙 error handling', () => {
     assert(error.response, undefined);
     assert.equal(error.response.data, notJSON);
   });
+
+  it('should support `instanceof` for GaxiosErrors of the same version', () => {
+    class A extends GaxiosError {}
+
+    const wrongVersion = {[GAXIOS_ERROR_SYMBOL]: '0.0.0'};
+    const correctVersion = {[GAXIOS_ERROR_SYMBOL]: pkg.version};
+    const child = new A('', {});
+
+    assert.equal(wrongVersion instanceof GaxiosError, false);
+    assert.equal(correctVersion instanceof GaxiosError, true);
+    assert.equal(child instanceof GaxiosError, true);
+  });
 });
 
 describe('🥁 configuration options', () => {