diff --git a/.changeset/plenty-tables-beg.md b/.changeset/plenty-tables-beg.md
new file mode 100644
index 00000000..0e115423
--- /dev/null
+++ b/.changeset/plenty-tables-beg.md
@@ -0,0 +1,5 @@
+---
+'@hono/zod-openapi': minor
+---
+
+extract range definitions to StatusCode
diff --git a/packages/zod-openapi/src/index.ts b/packages/zod-openapi/src/index.ts
index 786964af..96f670c2 100644
--- a/packages/zod-openapi/src/index.ts
+++ b/packages/zod-openapi/src/index.ts
@@ -27,7 +27,14 @@ import type {
   TypedResponse,
 } from 'hono'
 import type { MergePath, MergeSchemaPath } from 'hono/types'
-import type { StatusCode } from 'hono/utils/http-status'
+import type {
+  ClientErrorStatusCode,
+  InfoStatusCode,
+  RedirectStatusCode,
+  ServerErrorStatusCode,
+  StatusCode,
+  SuccessStatusCode,
+} from 'hono/utils/http-status'
 import type { Prettify, RemoveBlankRecord } from 'hono/utils/types'
 import { mergePath } from 'hono/utils/url'
 import type { AnyZodObject, ZodSchema, ZodError } from 'zod'
@@ -143,13 +150,28 @@ type ExtractContent<T> = T extends {
     : never
   : never
 
+type StatusCodeRangeDefinitions = {
+  '1XX': InfoStatusCode
+  '2XX': SuccessStatusCode
+  '3XX': RedirectStatusCode
+  '4XX': ClientErrorStatusCode
+  '5XX': ServerErrorStatusCode
+}
+type RouteConfigStatusCode = keyof StatusCodeRangeDefinitions | StatusCode
+type ExtractStatusCode<T extends RouteConfigStatusCode> = T extends keyof StatusCodeRangeDefinitions
+  ? StatusCodeRangeDefinitions[T]
+  : T
 export type RouteConfigToTypedResponse<R extends RouteConfig> = {
-  [Status in keyof R['responses'] & StatusCode]: IsJson<
+  [Status in keyof R['responses'] & RouteConfigStatusCode]: IsJson<
     keyof R['responses'][Status]['content']
   > extends never
-    ? TypedResponse<{}, Status, string>
-    : TypedResponse<ExtractContent<R['responses'][Status]['content']>, Status, 'json'>
-}[keyof R['responses'] & StatusCode]
+    ? TypedResponse<{}, ExtractStatusCode<Status>, string>
+    : TypedResponse<
+        ExtractContent<R['responses'][Status]['content']>,
+        ExtractStatusCode<Status>,
+        'json'
+      >
+}[keyof R['responses'] & RouteConfigStatusCode]
 
 export type Hook<T, E extends Env, P extends string, R> = (
   result:
diff --git a/packages/zod-openapi/test/index.test.ts b/packages/zod-openapi/test/index.test.ts
index 40efe279..e3286846 100644
--- a/packages/zod-openapi/test/index.test.ts
+++ b/packages/zod-openapi/test/index.test.ts
@@ -4,6 +4,7 @@ import { hc } from 'hono/client'
 import { describe, it, expect, expectTypeOf } from 'vitest'
 import { OpenAPIHono, createRoute, z, RouteConfigToTypedResponse } from '../src/index'
 import { Expect, Equal } from 'hono/utils/types'
+import { ServerErrorStatusCode } from 'hono/utils/http-status'
 
 describe('Constructor', () => {
   it('Should not require init object', () => {
@@ -200,11 +201,19 @@ describe('Basic - params', () => {
             responses: {
               '200': {
                 description: 'Get the user',
-                content: { 'application/json': { schema: { $ref: '#/components/schemas/User' } } },
+                content: {
+                  'application/json': {
+                    schema: { $ref: '#/components/schemas/User' },
+                  },
+                },
               },
               '400': {
                 description: 'Error!',
-                content: { 'application/json': { schema: { $ref: '#/components/schemas/Error' } } },
+                content: {
+                  'application/json': {
+                    schema: { $ref: '#/components/schemas/Error' },
+                  },
+                },
               },
             },
           },
@@ -1465,6 +1474,14 @@ describe('RouteConfigToTypedResponse', () => {
           },
           description: 'Error!',
         },
+        '5XX': {
+          content: {
+            'application/json': {
+              schema: ErrorSchema,
+            },
+          },
+          description: 'Server Error!',
+        },
       },
     }
 
@@ -1486,6 +1503,13 @@ describe('RouteConfigToTypedResponse', () => {
           400,
           'json'
         >
+      | TypedResponse<
+          {
+            ok: boolean
+          },
+          ServerErrorStatusCode,
+          'json'
+        >
     type verify = Expect<Equal<Expected, Actual>>
   })
 })