diff --git a/.changeset/cold-dingos-give.md b/.changeset/cold-dingos-give.md
new file mode 100644
index 00000000000..d9eaf08d3d9
--- /dev/null
+++ b/.changeset/cold-dingos-give.md
@@ -0,0 +1,5 @@
+---
+'@hyperlane-xyz/sdk': patch
+---
+
+Optimize HyperlaneRelayer routing config derivation
diff --git a/typescript/sdk/src/core/HyperlaneRelayer.ts b/typescript/sdk/src/core/HyperlaneRelayer.ts
index 27341a773fa..cb0ba570e90 100644
--- a/typescript/sdk/src/core/HyperlaneRelayer.ts
+++ b/typescript/sdk/src/core/HyperlaneRelayer.ts
@@ -75,12 +75,18 @@ export class HyperlaneRelayer {
   async getHookConfig(
     chain: ChainName,
     hook: Address,
+    messageContext?: DispatchedMessage,
   ): Promise<DerivedHookConfig> {
     let config: DerivedHookConfig | undefined;
     if (this.cache?.hook[chain]?.[hook]) {
       config = this.cache.hook[chain][hook] as DerivedHookConfig | undefined;
     } else {
-      const evmHookReader = new EvmHookReader(this.multiProvider, chain);
+      const evmHookReader = new EvmHookReader(
+        this.multiProvider,
+        chain,
+        undefined,
+        messageContext,
+      );
       config = await evmHookReader.deriveHookConfig(hook);
     }
 
@@ -98,12 +104,18 @@ export class HyperlaneRelayer {
   async getIsmConfig(
     chain: ChainName,
     ism: Address,
+    messageContext?: DispatchedMessage,
   ): Promise<DerivedIsmConfig> {
     let config: DerivedIsmConfig | undefined;
     if (this.cache?.ism[chain]?.[ism]) {
       config = this.cache.ism[chain][ism] as DerivedIsmConfig | undefined;
     } else {
-      const evmIsmReader = new EvmIsmReader(this.multiProvider, chain);
+      const evmIsmReader = new EvmIsmReader(
+        this.multiProvider,
+        chain,
+        undefined,
+        messageContext,
+      );
       config = await evmIsmReader.deriveIsmConfig(ism);
     }
 
@@ -124,7 +136,7 @@ export class HyperlaneRelayer {
   ): Promise<DerivedHookConfig> {
     const originChain = this.core.getOrigin(message);
     const hook = await this.core.getSenderHookAddress(message);
-    return this.getHookConfig(originChain, hook);
+    return this.getHookConfig(originChain, hook, message);
   }
 
   async getRecipientIsmConfig(
@@ -132,7 +144,7 @@ export class HyperlaneRelayer {
   ): Promise<DerivedIsmConfig> {
     const destinationChain = this.core.getDestination(message);
     const ism = await this.core.getRecipientIsmAddress(message);
-    return this.getIsmConfig(destinationChain, ism);
+    return this.getIsmConfig(destinationChain, ism, message);
   }
 
   async relayMessage(
diff --git a/typescript/sdk/src/hook/EvmHookReader.ts b/typescript/sdk/src/hook/EvmHookReader.ts
index 518b63e5850..1ed1f42ab79 100644
--- a/typescript/sdk/src/hook/EvmHookReader.ts
+++ b/typescript/sdk/src/hook/EvmHookReader.ts
@@ -26,6 +26,7 @@ import {
 } from '@hyperlane-xyz/utils';
 
 import { DEFAULT_CONTRACT_READ_CONCURRENCY } from '../consts/concurrency.js';
+import { DispatchedMessage } from '../core/types.js';
 import { MultiProvider } from '../providers/MultiProvider.js';
 import { ChainNameOrId } from '../types.js';
 import { HyperlaneReader } from '../utils/HyperlaneReader.js';
@@ -96,6 +97,7 @@ export class EvmHookReader extends HyperlaneReader implements HookReader {
     protected readonly concurrency: number = multiProvider.tryGetRpcConcurrency(
       chain,
     ) ?? DEFAULT_CONTRACT_READ_CONCURRENCY,
+    protected readonly messageContext?: DispatchedMessage,
   ) {
     super(multiProvider, chain);
   }
@@ -379,6 +381,7 @@ export class EvmHookReader extends HyperlaneReader implements HookReader {
     address: Address,
   ): Promise<WithAddress<DomainRoutingHookConfig>> {
     const hook = DomainRoutingHook__factory.connect(address, this.provider);
+
     this.assertHookType(await hook.hookType(), OnchainHookType.ROUTING);
 
     const owner = await hook.owner();
@@ -403,6 +406,7 @@ export class EvmHookReader extends HyperlaneReader implements HookReader {
       address,
       this.provider,
     );
+
     this.assertHookType(
       await hook.hookType(),
       OnchainHookType.FALLBACK_ROUTING,
@@ -430,7 +434,9 @@ export class EvmHookReader extends HyperlaneReader implements HookReader {
   private async fetchDomainHooks(
     hook: DomainRoutingHook | FallbackDomainRoutingHook,
   ): Promise<RoutingHookConfig['domains']> {
-    const domainIds = this.multiProvider.getKnownDomainIds();
+    const domainIds = this.messageContext
+      ? [this.messageContext.parsed.destination]
+      : this.multiProvider.getKnownDomainIds();
 
     const domainHooks: RoutingHookConfig['domains'] = {};
     await concurrentMap(this.concurrency, domainIds, async (domainId) => {
diff --git a/typescript/sdk/src/ism/EvmIsmReader.ts b/typescript/sdk/src/ism/EvmIsmReader.ts
index c7d766e8cab..47e58d2b76d 100644
--- a/typescript/sdk/src/ism/EvmIsmReader.ts
+++ b/typescript/sdk/src/ism/EvmIsmReader.ts
@@ -1,4 +1,4 @@
-import { ethers } from 'ethers';
+import { BigNumber, ethers } from 'ethers';
 
 import {
   ArbL2ToL1Ism__factory,
@@ -21,6 +21,7 @@ import {
 } from '@hyperlane-xyz/utils';
 
 import { DEFAULT_CONTRACT_READ_CONCURRENCY } from '../consts/concurrency.js';
+import { DispatchedMessage } from '../core/types.js';
 import { MultiProvider } from '../providers/MultiProvider.js';
 import { ChainNameOrId } from '../types.js';
 import { HyperlaneReader } from '../utils/HyperlaneReader.js';
@@ -66,6 +67,7 @@ export class EvmIsmReader extends HyperlaneReader implements IsmReader {
     protected readonly concurrency: number = multiProvider.tryGetRpcConcurrency(
       chain,
     ) ?? DEFAULT_CONTRACT_READ_CONCURRENCY,
+    protected readonly messageContext?: DispatchedMessage,
   ) {
     super(multiProvider, chain);
   }
@@ -129,11 +131,14 @@ export class EvmIsmReader extends HyperlaneReader implements IsmReader {
       address,
       this.provider,
     );
+
     const owner = await ism.owner();
     this.assertModuleType(await ism.moduleType(), ModuleType.ROUTING);
 
+    const domainIds = this.messageContext
+      ? [BigNumber.from(this.messageContext.parsed.origin)]
+      : await ism.domains();
     const domains: RoutingIsmConfig['domains'] = {};
-    const domainIds = await ism.domains();
 
     await concurrentMap(this.concurrency, domainIds, async (domainId) => {
       const chainName = this.multiProvider.tryGetChainName(domainId.toNumber());