diff --git a/clang/lib/Sema/Sema.cpp b/clang/lib/Sema/Sema.cpp
index 2e989f0ba6fe45..19d8692ee64849 100644
--- a/clang/lib/Sema/Sema.cpp
+++ b/clang/lib/Sema/Sema.cpp
@@ -310,6 +310,13 @@ void Sema::addImplicitTypedef(StringRef Name, QualType T) {
 }
 
 void Sema::Initialize() {
+  // Create BuiltinVaListDecl *before* ExternalSemaSource::InitializeSema(this)
+  // because during initialization ASTReader can emit globals that require
+  // name mangling. And the name mangling uses BuiltinVaListDecl.
+  if (Context.getTargetInfo().hasBuiltinMSVaList())
+    (void)Context.getBuiltinMSVaListDecl();
+  (void)Context.getBuiltinVaListDecl();
+
   if (SemaConsumer *SC = dyn_cast<SemaConsumer>(&Consumer))
     SC->InitializeSema(*this);
 
diff --git a/clang/test/Modules/builtin-vararg.c b/clang/test/Modules/builtin-vararg.c
new file mode 100644
index 00000000000000..ed6e6aeb6e50f5
--- /dev/null
+++ b/clang/test/Modules/builtin-vararg.c
@@ -0,0 +1,83 @@
+// Check how builtins using varargs behave with the modules.
+
+// RUN: rm -rf %t
+// RUN: split-file %s %t
+
+// RUN: %clang_cc1 -triple x86_64-apple-darwin \
+// RUN:   -fmodules -fno-implicit-modules -fbuiltin-headers-in-system-modules \
+// RUN:   -emit-module -fmodule-name=DeclareVarargs \
+// RUN:   -x c %t/include/module.modulemap -o %t/DeclareVarargs.pcm \
+// RUN:   -fmodule-map-file=%t/resource_dir/module.modulemap -isystem %t/resource_dir
+// RUN: %clang_cc1 -triple x86_64-apple-darwin \
+// RUN:   -fmodules -fno-implicit-modules -fbuiltin-headers-in-system-modules \
+// RUN:   -emit-pch -fmodule-name=Prefix \
+// RUN:   -x c-header %t/prefix.pch -o %t/prefix.pch.gch \
+// RUN:   -fmodule-map-file=%t/include/module.modulemap -fmodule-file=DeclareVarargs=%t/DeclareVarargs.pcm \
+// RUN:   -I %t/include
+// RUN: %clang_cc1 -triple x86_64-apple-darwin \
+// RUN:   -fmodules -fno-implicit-modules -fbuiltin-headers-in-system-modules \
+// RUN:   -emit-obj -fmodule-name=test \
+// RUN:   -x c %t/test.c -o %t/test.o \
+// RUN:   -Werror=incompatible-pointer-types \
+// RUN:   -fmodule-file=%t/DeclareVarargs.pcm -include-pch %t/prefix.pch.gch \
+// RUN:   -I %t/include
+
+//--- include/declare-varargs.h
+#ifndef DECLARE_VARARGS_H
+#define DECLARE_VARARGS_H
+
+#include <stdarg.h>
+
+int vprintf(const char *format, va_list args);
+
+// 1. initializeBuiltins 'acos' causes its deserialization and deserialization
+//    of 'implementation_of_builtin'. Because this is done before Sema initialization,
+//    'implementation_of_builtin' DeclID is added to PreloadedDeclIDs.
+#undef acos
+#define acos(__x) implementation_of_builtin(__x)
+
+// 2. Because of 'static' the function isn't added to EagerlyDeserializedDecls
+//    and not deserialized in `ASTReader::StartTranslationUnit` before `ASTReader::InitializeSema`.
+// 3. Because of '__overloadable__' attribute the function requires name mangling during deserialization.
+//    And the name mangling requires '__builtin_va_list' decl.
+//    Because the function is added to PreloadedDeclIDs, the deserialization happens in `ASTReader::InitializeSema`.
+static int __attribute__((__overloadable__)) implementation_of_builtin(int x) {
+  return x;
+}
+
+#endif // DECLARE_VARARGS_H
+
+//--- include/module.modulemap
+module DeclareVarargs {
+  header "declare-varargs.h"
+  export *
+}
+
+//--- resource_dir/stdarg.h
+#ifndef STDARG_H
+#define STDARG_H
+
+typedef __builtin_va_list va_list;
+#define va_start(ap, param) __builtin_va_start(ap, param)
+#define va_end(ap) __builtin_va_end(ap)
+
+#endif // STDARG_H
+
+//--- resource_dir/module.modulemap
+module _Builtin_stdarg {
+  header "stdarg.h"
+  export *
+}
+
+//--- prefix.pch
+#include <declare-varargs.h>
+
+//--- test.c
+#include <declare-varargs.h>
+
+void test(const char *format, ...) {
+  va_list argParams;
+  va_start(argParams, format);
+  vprintf(format, argParams);
+  va_end(argParams);
+}