diff --git a/core/lib/basic_types/src/web3/mod.rs b/core/lib/basic_types/src/web3/mod.rs
index be785040d2d..a2166d62710 100644
--- a/core/lib/basic_types/src/web3/mod.rs
+++ b/core/lib/basic_types/src/web3/mod.rs
@@ -61,9 +61,13 @@ impl Serialize for Bytes {
     where
         S: Serializer,
     {
-        let mut serialized = "0x".to_owned();
-        serialized.push_str(&hex::encode(&self.0));
-        serializer.serialize_str(serialized.as_ref())
+        if serializer.is_human_readable() {
+            let mut serialized = "0x".to_owned();
+            serialized.push_str(&hex::encode(&self.0));
+            serializer.serialize_str(serialized.as_ref())
+        } else {
+            serializer.serialize_bytes(&self.0)
+        }
     }
 }
 
@@ -72,7 +76,11 @@ impl<'a> Deserialize<'a> for Bytes {
     where
         D: Deserializer<'a>,
     {
-        deserializer.deserialize_identifier(BytesVisitor)
+        if deserializer.is_human_readable() {
+            deserializer.deserialize_identifier(BytesVisitor)
+        } else {
+            Vec::<u8>::deserialize(deserializer).map(Bytes)
+        }
     }
 }
 
diff --git a/core/lib/basic_types/src/web3/tests.rs b/core/lib/basic_types/src/web3/tests.rs
index e7c0a0d048a..bbeaece0374 100644
--- a/core/lib/basic_types/src/web3/tests.rs
+++ b/core/lib/basic_types/src/web3/tests.rs
@@ -83,3 +83,12 @@ fn block_can_be_deserialized() {
     let block: Block<H256> = serde_json::from_str(pre_dencun).unwrap();
     assert!(block.excess_blob_gas.is_none());
 }
+
+#[test]
+fn test_bytes_serde() {
+    use bincode::{deserialize, serialize};
+    let original = Bytes(vec![0, 1, 2, 3, 4]);
+    let encoded: Vec<u8> = serialize(&original).unwrap();
+    let decoded: Bytes = deserialize(&encoded).unwrap();
+    assert_eq!(original, decoded);
+}