diff --git a/.github/workflows/pythonpackage.yml b/.github/workflows/pythonpackage.yml
index 9099c8de..0d4fad34 100644
--- a/.github/workflows/pythonpackage.yml
+++ b/.github/workflows/pythonpackage.yml
@@ -1,15 +1,7 @@
 name: Python package
-
-on:
-  push:
-    branches: [ master ]
-  pull_request:
-    branches: [ master ]
-  workflow_dispatch:
-
+on: [push]
 jobs:
   build:
-
     runs-on: ubuntu-latest
     strategy:
       matrix:
@@ -23,19 +15,15 @@ jobs:
         python-version: ${{ matrix.python-version }}
     - name: Install dependencies
       run: |
-        python -m pip install --upgrade pip setuptools
-        pip install -e .[pywavefront,trimesh]
-        pip install -r tests/requirements.txt
-        # pip install -r requirements.txt
+        python -m pip install --upgrade pip
+        pip install -e .[tests]
     - name: Lint with flake8
       run: |
-        # pip install flake8
         # stop the build if there are Python syntax errors or undefined names
         flake8 . --count --select=E9,F63,F7,F82 --show-source --statistics
         # exit-zero treats all errors as warnings. The GitHub editor is 127 chars wide
         flake8 . --count --exit-zero --max-complexity=10 --max-line-length=127 --statistics
     - name: Test with pytest
       run: |
-        pip install pytest
         # TODO: Figure out if we can run headless tests
         pytest tests/test_docs.py
diff --git a/.readthedocs.yml b/.readthedocs.yml
index 47d1b0c1..3929f5f7 100644
--- a/.readthedocs.yml
+++ b/.readthedocs.yml
@@ -1,8 +1,10 @@
-build:
-  image: latest
-
-python:
-  version: 3.8
-  setup_py_install: true
-  install:
-    - requirements: docs/requirements.txt
+build:
+  image: latest
+
+python:
+  version: 3.8
+  install:
+    - method: pip
+      path: .
+      extra_requirements:
+        - docs
diff --git a/README.md b/README.md
index ae344128..6c16f8d8 100644
--- a/README.md
+++ b/README.md
@@ -38,7 +38,7 @@ you provide us your `moderngl.Context`.
 ## Install
 
 ```bash
-pip install moderngl-window
+$ pip install moderngl-window
 ```
 
 ## Supported Platforms
@@ -67,13 +67,13 @@ Test.run()
 Run the example with different window backends:
 
 ```bash
-python test.py --window pyglet
-python test.py --window pygame2
-python test.py --window glfw
-python test.py --window sdl2
-python test.py --window pyside2
-python test.py --window pyqt5
-python test.py --window tk
+$ python test.py --window pyglet
+$ python test.py --window pygame2
+$ python test.py --window glfw
+$ python test.py --window sdl2
+$ python test.py --window pyside2
+$ python test.py --window pyqt5
+$ python test.py --window tk
 ```
 
 `WindowConfig` classes are the simplest way to get started without knowing
@@ -88,9 +88,8 @@ We assume the user knows how to handle virtualenvs.
 # Install the package in editable mode
 $ pip install -e .
 
-# Set up and dev requirements
-pip install -r requirements.txt
-pip install -r tests/requirements.txt
+# Install test and development requirements
+$ pip install -e .[tests]
 ```
 
 ## Running Tests
@@ -98,19 +97,19 @@ pip install -r tests/requirements.txt
 Tests are set up with `tox` running pytest with coverage and flake8.
 
 ```bash
-pip install -r tests/requirements.txt
-tox -e py36
-tox -e py37
-tox -e py38
-tox -e py39
-tox -e pep8
+$ pip install -e .[tests]
+$ tox -e py36
+$ tox -e py37
+$ tox -e py38
+$ tox -e py39
+$ tox -e pep8
 ```
 
 ## Building Docs
 
 ```bash
-pip install -r docs/requirements.txt
-python setup.py build_sphinx
+$ pip install -e .[docs]
+$ sphinx-build -b html docs docs/_build
 ```
 
 ## Contributing
diff --git a/docs/requirements.txt b/docs/requirements.txt
deleted file mode 100644
index 0dddbb45..00000000
--- a/docs/requirements.txt
+++ /dev/null
@@ -1,4 +0,0 @@
-Sphinx==2.2.0
-sphinx-rtd-theme==0.4.3
-sphinxcontrib-napoleon==0.7
-doc8
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 00000000..2987d193
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,70 @@
+[project]
+name = "moderngl-window"
+version = "2.4.4"
+description = "A cross platform helper library for ModernGL making window creation and resource loading simple"
+readme = "README.md"
+authors = [
+    {name="Einar Forselv", email="eforselv@gmail.com"}
+]
+requires-python = ">=3.8"
+license = {file = "license.rst"}
+classifiers = [
+    "License :: OSI Approved :: MIT License",
+    "Operating System :: OS Independent",
+    "Topic :: Games/Entertainment",
+    "Topic :: Multimedia :: Graphics",
+    "Topic :: Multimedia :: Graphics :: 3D Rendering",
+    "Topic :: Scientific/Engineering :: Visualization",
+    "Programming Language :: Python :: 3 :: Only",
+    "Programming Language :: Python :: 3.8",
+    "Programming Language :: Python :: 3.9",
+    "Programming Language :: Python :: 3.10",
+    "Programming Language :: Python :: 3.11",
+]
+# zip-safe = false
+dependencies = [
+    "moderngl<6",
+    "pyglet~=2.0.0",
+    "numpy>=1.16,<2",
+    "pyrr>=0.10.3,<1",
+    "Pillow>=9,<10",
+]
+
+[tool.setuptools.packages.find]
+include = ["moderngl_window", "moderngl_window.*"]
+
+[project.optional-dependencies]
+dev = [
+    "pytest",
+    "mypy",
+    "flake8",
+    "coverage",
+]
+docs = [
+    "Sphinx==2.2.0",
+    "sphinx-rtd-theme==0.4.3",
+    "sphinxcontrib-napoleon==0.7",
+    "doc8",
+]
+pygame = ["pygame>=2.0.1"]
+pygame-ce = ["pygame-ce>=2.0.1"]
+tk = ["pyopengltk>=0.0.3"]
+trimesh = ["trimesh>=3.2.6,<4"]
+pywavefront = ["pywavefront>=1.2.0,<2"]
+PySDL2 = ["PySDL2"]
+glfw = ["glfw"]
+pyqt5 = ["PyQt5"]
+PySide2 = ["PySide2<6"]
+pdf = ["ReportLab>=1.2"]
+
+[project.urls]
+Source = "https://github.com/moderngl/moderngl_window"
+Documentation = "https://moderngl-window.readthedocs.io"
+ModernGL = "https://github.com/moderngl/moderngl"
+
+[tool.coverage.run]
+source = ["moderngl_window"]
+
+[build-system]
+requires = ["setuptools", "wheel"]
+build-backend = "setuptools.build_meta"
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index 5ad43e9c..00000000
--- a/requirements.txt
+++ /dev/null
@@ -1,27 +0,0 @@
-# For quick install of optional requirements in development
-# Get the main requirements by installing the package in editable mode:
-# pip install -e .
-
-moderngl<6
-
-# Optional
-pyglet<2
-PySide2<6
-PyQt5<6
-glfw<2
-PySDL2<1
-pygame>=2.0.1
-pyrr>=0.10
-pywavefront>=1.2.0,<2.0
-numpy>=1.16
-imgui<2
-
-# trimesh
-trimesh>=3.2.6
-scipy>=1.3.2
-
-# tkinter window
-pyopengl>=3.1.0
-pyopengltk>=0.0.3
-
-flake8
diff --git a/setup.cfg b/setup.cfg
deleted file mode 100644
index b88034e4..00000000
--- a/setup.cfg
+++ /dev/null
@@ -1,2 +0,0 @@
-[metadata]
-description-file = README.md
diff --git a/setup.py b/setup.py
deleted file mode 100644
index 12a0000a..00000000
--- a/setup.py
+++ /dev/null
@@ -1,52 +0,0 @@
-from setuptools import setup, find_namespace_packages
-
-setup(
-    name="moderngl-window",
-    version="2.4.4",
-    description="A cross platform helper library for ModernGL making window creation and resource loading simple",
-    long_description=open('README.md').read(),
-    long_description_content_type='text/markdown',
-    url="https://github.com/moderngl/moderngl_window",
-    author="Einar Forselv",
-    author_email="eforselv@gmail.com",
-    packages=find_namespace_packages(include=['moderngl_window', 'moderngl_window.*']),
-    include_package_data=True,
-    keywords=['moderngl', 'window', 'context'],
-    license='MIT',
-    platforms=['any'],
-    python_requires='>=3.7',
-    classifiers=[
-        'License :: OSI Approved :: MIT License',
-        'Operating System :: OS Independent',
-        'Topic :: Games/Entertainment',
-        'Topic :: Multimedia :: Graphics',
-        'Topic :: Multimedia :: Graphics :: 3D Rendering',
-        'Topic :: Scientific/Engineering :: Visualization',
-        'Programming Language :: Python :: 3 :: Only',
-        'Programming Language :: Python :: 3.8',
-        'Programming Language :: Python :: 3.9',
-        'Programming Language :: Python :: 3.10',
-        'Programming Language :: Python :: 3.11',
-    ],
-    install_requires=[
-        'moderngl<6',
-        'pyglet>=2.0dev23',
-        'numpy>=1.16,<2',
-        'pyrr>=0.10.3,<1',
-        'Pillow>=9,<10',
-    ],
-    extras_require={
-        "PySide2": ['PySide2<6'],
-        "pyqt5": ['PyQt5'],
-        "glfw": ['glfw'],
-        "PySDL2": ['PySDL2'],
-        "pywavefront": ["pywavefront>=1.3.3,<2"],
-        "trimesh": ["trimesh>=3.2.6,<4", "scipy>=1.3.2"],
-        "tk": ["pyopengltk>=0.0.3"],
-        "pygame": ["pygame>=2.1.2"],
-    },
-    project_urls={
-        'Documentation': 'https://moderngl-window.readthedocs.io',
-        'ModernGL': 'https://github.com/moderngl/moderngl',
-    },
-)
diff --git a/tests/requirements.txt b/tests/requirements.txt
deleted file mode 100644
index fad52503..00000000
--- a/tests/requirements.txt
+++ /dev/null
@@ -1,4 +0,0 @@
-pytest
-tox
-flake8
-coverage
diff --git a/tox.ini b/tox.ini
index 14c044bf..a315cf1a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -2,15 +2,21 @@
 # as flake8 can fail to parse the file on OS X and Windows
 
 [tox]
-skipsdist = False
+skipsdist = True
 envlist =
     py36
     py37
     py38
     py39
-    py310
     pep8
 
+[gh-actions]
+python =
+    3.6: py36
+    3.7: py37
+    3.8: py38
+    3.9: py39
+
 [testenv]
 usedevelop = True
 basepython =
@@ -18,13 +24,9 @@ basepython =
     py37: python3.7
     py38: python3.8
     py39: python3.9
-    py310: python3.10
-
-deps = 
-    -r{toxinidir}/requirements.txt
-    -r{toxinidir}/tests/requirements.txt
+extras = tests
 commands =
-    coverage run --source=moderngl_window -m pytest tests/
+    coverage run -m pytest tests/
     coverage report
 
 [testenv:pep8]