diff --git a/.cargo/config.toml b/.cargo/config.toml
index 3c32d25..2afeb28 100644
--- a/.cargo/config.toml
+++ b/.cargo/config.toml
@@ -1,2 +1,5 @@
 [target.aarch64-unknown-linux-gnu]
 linker = "aarch64-linux-gnu-gcc"
+[target.aarch64-unknown-linux-musl]
+linker = "aarch64-linux-musl-gcc"
+rustflags = ["-C", "target-feature=-crt-static"]
diff --git a/.github/workflows/CI.yml b/.github/workflows/CI.yml
index 51d8ee6..3518d50 100644
--- a/.github/workflows/CI.yml
+++ b/.github/workflows/CI.yml
@@ -18,7 +18,7 @@ env:
   pull_request: null
 jobs:
   build:
-    if: '!contains(github.event.head_commit.message, ''skip ci'')'
+    if: "!contains(github.event.head_commit.message, 'skip ci')"
     strategy:
       fail-fast: false
       matrix:
@@ -42,6 +42,10 @@ jobs:
               rustup target add x86_64-unknown-linux-gnu &&
               npm run build -- --target x86_64-unknown-linux-gnu --zig --zig-abi-suffix 2.12 &&
               llvm-strip -x *.node
+          - host: ubuntu-latest
+            target: x86_64-unknown-linux-musl
+            docker: ghcr.io/napi-rs/napi-rs/nodejs-rust:lts-alpine
+            build: set -e && npm run build && strip *.node
           - host: macos-latest
             architecture: x64
             target: aarch64-apple-darwin
@@ -62,6 +66,14 @@ jobs:
               rustup target add aarch64-unknown-linux-gnu &&
               npm run build -- --target aarch64-unknown-linux-gnu --zig --zig-abi-suffix 2.17 &&
               llvm-strip -x *.node
+          - host: ubuntu-latest
+            target: aarch64-unknown-linux-musl
+            docker: ghcr.io/napi-rs/napi-rs/nodejs-rust:lts-alpine
+            build: |-
+              set -e &&
+              rustup target add aarch64-unknown-linux-musl &&
+              npm run build -- --target aarch64-unknown-linux-musl &&
+              /aarch64-linux-musl-cross/bin/aarch64-linux-musl-strip *.node
     name: stable - ${{ matrix.settings.target }} - node@16
     runs-on: ${{ matrix.settings.host }}
     steps:
@@ -204,6 +216,44 @@ jobs:
         shell: bash
       - name: Test bindings
         run: docker run --rm -v $(pwd):/build -w /build node:${{ matrix.node }}-slim npm test
+  test-linux-x64-musl-binding:
+    name: Test bindings on x86_64-unknown-linux-musl - node@${{ matrix.node }}
+    needs:
+      - build
+    strategy:
+      fail-fast: false
+      matrix:
+        node:
+          - '12'
+          - '14'
+          - '16'
+          - '18'
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v3
+      - name: Setup node
+        uses: actions/setup-node@v3
+        with:
+          node-version: ${{ matrix.node }}
+          check-latest: true
+          cache: npm
+      - name: Cache NPM dependencies
+        uses: actions/cache@v3
+        with:
+          path: node_modules
+          key: npm-cache-test-x86_64-unknown-linux-musl-${{ matrix.node }}-${{ hashFiles('package-lock.json') }}
+      - name: Install dependencies
+        run: npm clean-install --ignore-scripts
+      - name: Download artifacts
+        uses: actions/download-artifact@v3
+        with:
+          name: bindings-x86_64-unknown-linux-musl
+          path: .
+      - name: List packages
+        run: ls -R .
+        shell: bash
+      - name: Test bindings
+        run: docker run --rm -v $(pwd):/build -w /build node:${{ matrix.node }}-alpine npm test
   test-linux-aarch64-gnu-binding:
     name: Test bindings on aarch64-unknown-linux-gnu - node@${{ matrix.node }}
     needs:
@@ -244,13 +294,47 @@ jobs:
             set -e
             npm test
             ls -la
+  test-linux-aarch64-musl-binding:
+    name: Test bindings on aarch64-unknown-linux-musl - node@${{ matrix.node }}
+    needs:
+      - build
+    runs-on: ubuntu-latest
+    steps:
+      - run: docker run --rm --privileged multiarch/qemu-user-static:register --reset
+      - uses: actions/checkout@v3
+      - name: Download artifacts
+        uses: actions/download-artifact@v3
+        with:
+          name: bindings-aarch64-unknown-linux-musl
+          path: .
+      - name: List packages
+        run: ls -R .
+        shell: bash
+      - name: Cache NPM dependencies
+        uses: actions/cache@v3
+        with:
+          path: node_modules
+          key: npm-cache-test-linux-aarch64-musl-${{ matrix.node }}-${{ hashFiles('package-lock.json') }}
+      - name: Install dependencies
+        run: npm clean-install --ignore-scripts
+      - name: Setup and run tests
+        uses: addnab/docker-run-action@v3
+        with:
+          image: multiarch/alpine:aarch64-latest-stable
+          options: '-v ${{ github.workspace }}:/build -w /build'
+          run: |
+            set -e
+            apk add nodejs npm
+            npm test
   publish:
     name: Publish
     runs-on: ubuntu-latest
     needs:
       - test-macOS-windows-binding
       - test-linux-x64-gnu-binding
+      - test-linux-x64-musl-binding
       - test-linux-aarch64-gnu-binding
+      - test-linux-aarch64-musl-binding
     steps:
       - uses: actions/checkout@v3
       - name: Setup node
diff --git a/README.md b/README.md
index f721b12..12fe1a8 100644
--- a/README.md
+++ b/README.md
@@ -20,12 +20,14 @@ npm install @mongodb-js/zstd
 | Linux x64 gnu    | ✓      | ✓      | ✓      | ✓      |
 | Linux arm gnu    | ✓      | ✓      | ✓      | ✓      |
 | Linux arm64 gnu  | ✓      | ✓      | ✓      | ✓      |
+| Linux x64 musl   | ✓      | ✓      | ✓      | ✓      |
+| Linux arm64 musl | ✓      | ✓      | ✓      | ✓      |
 
 ## API
 
 ```ts
-export function compress(buffer: Buffer | ArrayBuffer | Uint8Array, level: number): Promise<Buffer>
-export function decompress(buffer: Buffer): Promise<Buffer>
+export function compress(buffer: Buffer | ArrayBuffer | Uint8Array, level: number): Promise<Buffer>;
+export function decompress(buffer: Buffer): Promise<Buffer>;
 ```
 
 ### Bugs / Feature Requests
diff --git a/index.js b/index.js
index 64354f1..e411226 100644
--- a/index.js
+++ b/index.js
@@ -7,6 +7,20 @@ let nativeBinding = null;
 let localFileExisted = false;
 let loadError = null;
 
+function isMusl() {
+  // For Node 10
+  if (!process.report || typeof process.report.getReport !== 'function') {
+    try {
+      return readFileSync('/usr/bin/ldd', 'utf8').includes('musl');
+    } catch (e) {
+      return true;
+    }
+  } else {
+    const { glibcVersionRuntime } = process.report.getReport().header;
+    return !glibcVersionRuntime;
+  }
+}
+
 switch (platform) {
   case 'win32':
     switch (arch) {
@@ -59,27 +73,53 @@ switch (platform) {
   case 'linux':
     switch (arch) {
       case 'x64':
-        localFileExisted = existsSync(join(__dirname, 'zstd.linux-x64-gnu.node'));
-        try {
-          if (localFileExisted) {
-            nativeBinding = require('./zstd.linux-x64-gnu.node');
-          } else {
-            nativeBinding = require('@mongodb-js/zstd-linux-x64-gnu');
+        if (isMusl()) {
+          localFileExisted = existsSync(join(__dirname, 'zstd.linux-x64-musl.node'));
+          try {
+            if (localFileExisted) {
+              nativeBinding = require('./zstd.linux-x64-musl.node');
+            } else {
+              nativeBinding = require('@mongodb-js/zstd-linux-x64-musl');
+            }
+          } catch (e) {
+            loadError = e;
+          }
+        } else {
+          localFileExisted = existsSync(join(__dirname, 'zstd.linux-x64-gnu.node'));
+          try {
+            if (localFileExisted) {
+              nativeBinding = require('./zstd.linux-x64-gnu.node');
+            } else {
+              nativeBinding = require('@mongodb-js/zstd-linux-x64-gnu');
+            }
+          } catch (e) {
+            loadError = e;
           }
-        } catch (e) {
-          loadError = e;
         }
         break;
       case 'arm64':
-        localFileExisted = existsSync(join(__dirname, 'zstd.linux-arm64-gnu.node'));
-        try {
-          if (localFileExisted) {
-            nativeBinding = require('./zstd.linux-arm64-gnu.node');
-          } else {
-            nativeBinding = require('@mongodb-js/zstd-linux-arm64-gnu');
+        if (isMusl()) {
+          localFileExisted = existsSync(join(__dirname, 'zstd.linux-arm64-musl.node'));
+          try {
+            if (localFileExisted) {
+              nativeBinding = require('./zstd.linux-arm64-musl.node');
+            } else {
+              nativeBinding = require('@mongodb-js/zstd-linux-arm64-musl');
+            }
+          } catch (e) {
+            loadError = e;
+          }
+        } else {
+          localFileExisted = existsSync(join(__dirname, 'zstd.linux-arm64-gnu.node'));
+          try {
+            if (localFileExisted) {
+              nativeBinding = require('./zstd.linux-arm64-gnu.node');
+            } else {
+              nativeBinding = require('@mongodb-js/zstd-linux-arm64-gnu');
+            }
+          } catch (e) {
+            loadError = e;
           }
-        } catch (e) {
-          loadError = e;
         }
         break;
       case 'arm':
diff --git a/npm/linux-arm64-musl/README.md b/npm/linux-arm64-musl/README.md
new file mode 100644
index 0000000..7547d39
--- /dev/null
+++ b/npm/linux-arm64-musl/README.md
@@ -0,0 +1,3 @@
+# `@mongodb-js/zstd-linux-arm64-musl`
+
+This is the **aarch64-unknown-linux-musl** binary for `@mongodb-js/zstd`
diff --git a/npm/linux-arm64-musl/package.json b/npm/linux-arm64-musl/package.json
new file mode 100644
index 0000000..9088e85
--- /dev/null
+++ b/npm/linux-arm64-musl/package.json
@@ -0,0 +1,21 @@
+{
+  "name": "@mongodb-js/zstd-linux-arm64-musl",
+  "version": "0.0.0",
+  "os": [
+    "linux"
+  ],
+  "cpu": [
+    "arm64"
+  ],
+  "main": "zstd.linux-arm64-musl.node",
+  "files": [
+    "zstd.linux-arm64-musl.node"
+  ],
+  "license": "MIT",
+  "engines": {
+    "node": ">= 10"
+  },
+  "libc": [
+    "musl"
+  ]
+}
diff --git a/npm/linux-x64-musl/README.md b/npm/linux-x64-musl/README.md
new file mode 100644
index 0000000..d656011
--- /dev/null
+++ b/npm/linux-x64-musl/README.md
@@ -0,0 +1,3 @@
+# `@mongodb-js/zstd-linux-x64-musl`
+
+This is the **x86_64-unknown-linux-musl** binary for `@mongodb-js/zstd`
diff --git a/npm/linux-x64-musl/package.json b/npm/linux-x64-musl/package.json
new file mode 100644
index 0000000..ebcebe2
--- /dev/null
+++ b/npm/linux-x64-musl/package.json
@@ -0,0 +1,21 @@
+{
+  "name": "@mongodb-js/zstd-linux-x64-musl",
+  "version": "0.0.0",
+  "os": [
+    "linux"
+  ],
+  "cpu": [
+    "x64"
+  ],
+  "main": "zstd.linux-x64-musl.node",
+  "files": [
+    "zstd.linux-x64-musl.node"
+  ],
+  "license": "MIT",
+  "engines": {
+    "node": ">= 10"
+  },
+  "libc": [
+    "musl"
+  ]
+}
diff --git a/package.json b/package.json
index cac8cf9..a3a8c1d 100644
--- a/package.json
+++ b/package.json
@@ -13,7 +13,9 @@
       "defaults": true,
       "additional": [
         "aarch64-apple-darwin",
-        "aarch64-unknown-linux-gnu"
+        "aarch64-unknown-linux-gnu",
+        "aarch64-unknown-linux-musl",
+        "x86_64-unknown-linux-musl"
       ]
     }
   },