diff --git a/.gitignore b/.gitignore
index 6a3811f2e..2b15cd664 100644
--- a/.gitignore
+++ b/.gitignore
@@ -12,7 +12,6 @@ scratch/
 s3/
 build/
 dist/
-.snakemake
 *stderr
 /docs/_build/
 
diff --git a/setup.py b/setup.py
index 6674da85a..d088744fe 100644
--- a/setup.py
+++ b/setup.py
@@ -79,7 +79,6 @@
             "pytest-cov >=2.8.1",
             "pytest-mock >= 2.0.0",
             "recommonmark >=0.5.0",
-            "snakemake >=5.4.0",
             "Sphinx >=2.0.1",
             "sphinx-autobuild >=2021.3.14",
             "sphinx-argparse >=0.2.5",