diff --git a/common.gypi b/common.gypi
index 88764c8f6b75a8..4e1f4fb24e454b 100644
--- a/common.gypi
+++ b/common.gypi
@@ -356,7 +356,10 @@
         ],
       }],
       ['v8_enable_pointer_compression == 1', {
-        'defines': ['V8_COMPRESS_POINTERS'],
+        'defines': [
+          'V8_COMPRESS_POINTERS',
+          'V8_COMPRESS_POINTERS_IN_ISOLATE_CAGE',
+        ],
       }],
       ['v8_enable_pointer_compression == 1 or v8_enable_31bit_smis_on_64bit_arch == 1', {
         'defines': ['V8_31BIT_SMIS_ON_64BIT_ARCH'],
diff --git a/tools/v8_gypfiles/features.gypi b/tools/v8_gypfiles/features.gypi
index 68da6ef3378904..6bb08bcebeca91 100644
--- a/tools/v8_gypfiles/features.gypi
+++ b/tools/v8_gypfiles/features.gypi
@@ -261,7 +261,10 @@
         'defines': ['ENABLE_MINOR_MC',],
       }],
       ['v8_enable_pointer_compression==1', {
-        'defines': ['V8_COMPRESS_POINTERS',],
+        'defines': [
+          'V8_COMPRESS_POINTERS',
+          'V8_COMPRESS_POINTERS_IN_ISOLATE_CAGE',
+        ],
       }],
       ['v8_enable_pointer_compression==1 or v8_enable_31bit_smis_on_64bit_arch==1', {
         'defines': ['V8_31BIT_SMIS_ON_64BIT_ARCH',],