diff --git a/CHANGELOG.md b/CHANGELOG.md
index 1298977849..51ecc94d8c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -39,6 +39,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
   ([#2971](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2971))
 - Drop `opentelemetry-instrumentation-test` package from default instrumentation list
   ([#2969](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2969))
+- `opentelemetry-instrumentation-httpx`: remove private unused `_InstrumentedClient` and `_InstrumentedAsyncClient` classes
+  ([#3036](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3036))
 
 ## Version 1.28.0/0.49b0 (2024-11-05)
 
diff --git a/instrumentation/opentelemetry-instrumentation-httpx/src/opentelemetry/instrumentation/httpx/__init__.py b/instrumentation/opentelemetry-instrumentation-httpx/src/opentelemetry/instrumentation/httpx/__init__.py
index 92e044bf06..195c784408 100644
--- a/instrumentation/opentelemetry-instrumentation-httpx/src/opentelemetry/instrumentation/httpx/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-httpx/src/opentelemetry/instrumentation/httpx/__init__.py
@@ -641,77 +641,6 @@ async def aclose(self) -> None:
         await self._transport.aclose()
 
 
-class _InstrumentedClient(httpx.Client):
-    _tracer_provider = None
-    _request_hook = None
-    _response_hook = None
-
-    def __init__(self, *args, **kwargs):
-        super().__init__(*args, **kwargs)
-
-        self._original_transport = self._transport
-        self._original_mounts = self._mounts.copy()
-        self._is_instrumented_by_opentelemetry = True
-
-        self._transport = SyncOpenTelemetryTransport(
-            self._transport,
-            tracer_provider=_InstrumentedClient._tracer_provider,
-            request_hook=_InstrumentedClient._request_hook,
-            response_hook=_InstrumentedClient._response_hook,
-        )
-        self._mounts.update(
-            {
-                url_pattern: (
-                    SyncOpenTelemetryTransport(
-                        transport,
-                        tracer_provider=_InstrumentedClient._tracer_provider,
-                        request_hook=_InstrumentedClient._request_hook,
-                        response_hook=_InstrumentedClient._response_hook,
-                    )
-                    if transport is not None
-                    else transport
-                )
-                for url_pattern, transport in self._original_mounts.items()
-            }
-        )
-
-
-class _InstrumentedAsyncClient(httpx.AsyncClient):
-    _tracer_provider = None
-    _request_hook = None
-    _response_hook = None
-
-    def __init__(self, *args, **kwargs):
-        super().__init__(*args, **kwargs)
-
-        self._original_transport = self._transport
-        self._original_mounts = self._mounts.copy()
-        self._is_instrumented_by_opentelemetry = True
-
-        self._transport = AsyncOpenTelemetryTransport(
-            self._transport,
-            tracer_provider=_InstrumentedAsyncClient._tracer_provider,
-            request_hook=_InstrumentedAsyncClient._request_hook,
-            response_hook=_InstrumentedAsyncClient._response_hook,
-        )
-
-        self._mounts.update(
-            {
-                url_pattern: (
-                    AsyncOpenTelemetryTransport(
-                        transport,
-                        tracer_provider=_InstrumentedAsyncClient._tracer_provider,
-                        request_hook=_InstrumentedAsyncClient._request_hook,
-                        response_hook=_InstrumentedAsyncClient._response_hook,
-                    )
-                    if transport is not None
-                    else transport
-                )
-                for url_pattern, transport in self._original_mounts.items()
-            }
-        )
-
-
 class HTTPXClientInstrumentor(BaseInstrumentor):
     # pylint: disable=protected-access,attribute-defined-outside-init
     """An instrumentor for httpx Client and AsyncClient