diff --git a/packages/react-table/src/components/Table/Table.tsx b/packages/react-table/src/components/Table/Table.tsx
index 8dbaaf0a8d3..afd2b26c5f4 100644
--- a/packages/react-table/src/components/Table/Table.tsx
+++ b/packages/react-table/src/components/Table/Table.tsx
@@ -57,6 +57,8 @@ export interface TableProps extends React.HTMLProps<HTMLTableElement>, OUIAProps
   isStriped?: boolean;
   /** Flag indicating this table contains expandable rows to maintain proper striping */
   isExpandable?: boolean;
+  /** Flag indicating this table's rows will not have the inset typically reserved for expanding/collapsing rows in a tree table. Intended for use on tree tables with no visible rows with children. */
+  hasNoInset?: boolean;
   /** Collection of column spans for nested headers. Deprecated: see https://github.com/patternfly/patternfly/issues/4584 */
   nestedHeaderColumnSpans?: number[];
   /** Visible text to add alongside the hidden a11y caption for tables with selectable rows. */
@@ -91,6 +93,7 @@ const TableBase: React.FunctionComponent<TableProps> = ({
   isNested = false,
   isStriped = false,
   isExpandable = false,
+  hasNoInset = false,
   // eslint-disable-next-line @typescript-eslint/no-unused-vars
   nestedHeaderColumnSpans,
   selectableRowCaptionText,
@@ -206,6 +209,7 @@ const TableBase: React.FunctionComponent<TableProps> = ({
           isTreeTable && stylesTreeView.modifiers.treeView,
           isStriped && styles.modifiers.striped,
           isExpandable && styles.modifiers.expandable,
+          hasNoInset && stylesTreeView.modifiers.noInset,
           isNested && 'pf-m-nested'
         )}
         ref={tableRef}
diff --git a/packages/react-table/src/components/Table/examples/Table.md b/packages/react-table/src/components/Table/examples/Table.md
index 4cb3c7875d5..3a8c8010614 100644
--- a/packages/react-table/src/components/Table/examples/Table.md
+++ b/packages/react-table/src/components/Table/examples/Table.md
@@ -297,6 +297,13 @@ the voice over technologies will recognize the flat table structure as a tree.
 ```ts file="TableTree.tsx"
 ```
 
+### Flat tree table with no inset
+
+To remove the inset used to leave space for the expand/collapse toggle in a flat tree table, use the `hasNoInset` prop on the `Table` component.
+
+```ts file="TableTreeNoInset.tsx"
+```
+
 ### Draggable row table
 
 To make a row draggable:
diff --git a/packages/react-table/src/components/Table/examples/TableTreeNoInset.tsx b/packages/react-table/src/components/Table/examples/TableTreeNoInset.tsx
new file mode 100644
index 00000000000..3c16708b9a6
--- /dev/null
+++ b/packages/react-table/src/components/Table/examples/TableTreeNoInset.tsx
@@ -0,0 +1,123 @@
+import React from 'react';
+import { Table, Thead, Tr, Th, Tbody, Td, TreeRowWrapper, TdProps } from '@patternfly/react-table';
+import LeafIcon from '@patternfly/react-icons/dist/esm/icons/leaf-icon';
+
+interface RepositoriesTreeNode {
+  name: string;
+  branches: string;
+  pullRequests: string;
+  workspaces: string;
+  children?: RepositoriesTreeNode[];
+}
+
+export const TableTreeNoInset: React.FunctionComponent = () => {
+  // In real usage, this data would come from some external source like an API via props.
+  const data: RepositoriesTreeNode[] = [
+    {
+      name: 'Repositories one',
+      branches: 'Branch one',
+      pullRequests: 'Pull request one',
+      workspaces: 'Workplace one',
+      children: []
+    },
+    {
+      name: 'Repositories seven',
+      branches: 'Branch seven',
+      pullRequests: 'Pull request seven',
+      workspaces: 'Workplace seven',
+      children: []
+    },
+    {
+      name: 'Repositories nine',
+      branches: 'Branch nine',
+      pullRequests: 'Pull request nine',
+      workspaces: 'Workplace nine'
+    }
+  ];
+
+  const columnNames = {
+    name: 'Repositories',
+    branches: 'Branches',
+    prs: 'Pull requests',
+    workspaces: 'Workspaces'
+  };
+
+  const [selectedNodeNames, setSelectedNodeNames] = React.useState<string[]>([]);
+  const isNodeChecked = (node: RepositoriesTreeNode) => selectedNodeNames.includes(node.name);
+
+  /**
+   Recursive function which flattens the data into an array of flattened TreeRowWrapper components
+   params:
+   - nodes - array of a single level of tree nodes
+   - level - number representing how deeply nested the current row is
+   - posinset - position of the row relative to this row's siblings
+   - currentRowIndex - position of the row relative to the entire table
+   - isHidden - defaults to false, true if this row's parent is expanded
+   */
+  const renderRows = (
+    [node, ...remainingNodes]: RepositoriesTreeNode[],
+    level = 1,
+    posinset = 1,
+    rowIndex = 0,
+    isHidden = false
+  ): React.ReactNode[] => {
+    if (!node) {
+      return [];
+    }
+    const isChecked = isNodeChecked(node);
+    const icon = <LeafIcon />;
+
+    const treeRow: TdProps['treeRow'] = {
+      onCollapse: () => {},
+      onToggleRowDetails: () => {},
+      onCheckChange: (_event, isChecking) => {
+        setSelectedNodeNames(prevSelected => {
+          const otherSelectedNodeNames = prevSelected.filter(name => name === node.name);
+          return !isChecking ? otherSelectedNodeNames : [...otherSelectedNodeNames, node.name];
+        });
+      },
+      rowIndex,
+      props: {
+        isHidden,
+        'aria-level': level,
+        'aria-posinset': posinset,
+        'aria-setsize': node.children ? node.children.length : 0,
+        isChecked,
+        checkboxId: `flat_checkbox_id_${node.name.toLowerCase().replace(/\s+/g, '_')}`,
+        icon
+      }
+    };
+
+    const childRows =
+      node.children && node.children.length
+        ? renderRows(node.children, level + 1, 1, rowIndex + 1, isHidden)
+        : [];
+
+    return [
+      <TreeRowWrapper key={node.name} row={{ props: treeRow.props }}>
+        <Td dataLabel={columnNames.name} treeRow={treeRow}>
+          {node.name}
+        </Td>
+        <Td dataLabel={columnNames.branches}>{node.branches}</Td>
+        <Td dataLabel={columnNames.prs}>{node.pullRequests}</Td>
+        <Td dataLabel={columnNames.workspaces}>{node.workspaces}</Td>
+      </TreeRowWrapper>,
+      ...childRows,
+      ...renderRows(remainingNodes, level, posinset + 1, rowIndex + 1 + childRows.length, isHidden)
+    ];
+  };
+
+  return (
+    <Table isTreeTable aria-label="Tree table" hasNoInset>
+      <Thead>
+        <Tr>
+          <Th width={40}>{columnNames.name}</Th>
+          <Th>{columnNames.branches}</Th>
+          <Th>{columnNames.prs}</Th>
+          <Th>{columnNames.workspaces}</Th>
+        </Tr>
+      </Thead>
+      <Tbody>{renderRows(data)}</Tbody>
+    </Table>
+  );
+};