diff --git a/executor/seqtest/prepared_test.go b/executor/seqtest/prepared_test.go
index 11dae5e570767..5edbed52b4e13 100644
--- a/executor/seqtest/prepared_test.go
+++ b/executor/seqtest/prepared_test.go
@@ -420,14 +420,14 @@ func TestPreparedInsert(t *testing.T) {
 			err = counter.Write(pb)
 			require.NoError(t, err)
 			hit := pb.GetCounter().GetValue()
-			require.Equal(t, float64(1), hit)
+			require.Equal(t, float64(0), hit) // insert-values-stmt cannot use the plan cache
 		}
 		tk.MustExec(`set @a=3,@b=3; execute stmt_insert using @a, @b;`)
 		if flag {
 			err = counter.Write(pb)
 			require.NoError(t, err)
 			hit := pb.GetCounter().GetValue()
-			require.Equal(t, float64(2), hit)
+			require.Equal(t, float64(0), hit)
 		}
 
 		result := tk.MustQuery("select id, c1 from prepare_test where id = ?", 1)
@@ -443,21 +443,21 @@ func TestPreparedInsert(t *testing.T) {
 			err = counter.Write(pb)
 			require.NoError(t, err)
 			hit := pb.GetCounter().GetValue()
-			require.Equal(t, float64(2), hit)
+			require.Equal(t, float64(0), hit)
 		}
 		tk.MustExec(`set @a=2; execute stmt_insert_select using @a;`)
 		if flag {
 			err = counter.Write(pb)
 			require.NoError(t, err)
 			hit := pb.GetCounter().GetValue()
-			require.Equal(t, float64(3), hit)
+			require.Equal(t, float64(1), hit)
 		}
 		tk.MustExec(`set @a=3; execute stmt_insert_select using @a;`)
 		if flag {
 			err = counter.Write(pb)
 			require.NoError(t, err)
 			hit := pb.GetCounter().GetValue()
-			require.Equal(t, float64(4), hit)
+			require.Equal(t, float64(2), hit)
 		}
 
 		result = tk.MustQuery("select id, c1 from prepare_test where id = ?", 101)
diff --git a/planner/core/plan_cache_test.go b/planner/core/plan_cache_test.go
index 7a4ac860d8593..a480c583d0434 100644
--- a/planner/core/plan_cache_test.go
+++ b/planner/core/plan_cache_test.go
@@ -221,6 +221,29 @@ func TestIssue38533(t *testing.T) {
 	tk.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("0"))
 }
 
+func TestIgnoreInsertStmt(t *testing.T) {
+	store := testkit.CreateMockStore(t)
+	tk := testkit.NewTestKit(t, store)
+	tk.MustExec("use test")
+	tk.MustExec("create table t (a int)")
+
+	// do not cache native insert-stmt
+	tk.MustExec("prepare st from 'insert into t values (1)'")
+	tk.MustExec("execute st")
+	tk.MustExec("execute st")
+	tk.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("0"))
+
+	// ignore-hint in insert-stmt can work
+	tk.MustExec("prepare st from 'insert into t select * from t'")
+	tk.MustExec("execute st")
+	tk.MustExec("execute st")
+	tk.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("1"))
+	tk.MustExec("prepare st from 'insert /*+ ignore_plan_cache() */ into t select * from t'")
+	tk.MustExec("execute st")
+	tk.MustExec("execute st")
+	tk.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("0"))
+}
+
 func TestIssue38710(t *testing.T) {
 	store := testkit.CreateMockStore(t)
 	tk := testkit.NewTestKit(t, store)
diff --git a/planner/core/plan_cacheable_checker.go b/planner/core/plan_cacheable_checker.go
index 3412ace379271..041509d224792 100644
--- a/planner/core/plan_cacheable_checker.go
+++ b/planner/core/plan_cacheable_checker.go
@@ -94,6 +94,21 @@ func (checker *cacheableChecker) Enter(in ast.Node) (out ast.Node, skipChildren
 				return in, true
 			}
 		}
+	case *ast.InsertStmt:
+		if node.Select == nil {
+			// do not cache insert-values-stmt like 'insert into t values (...)' since
+			// no performance benefit and to save memory.
+			checker.cacheable = false
+			checker.reason = "ignore insert-values-stmt"
+			return in, true
+		}
+		for _, hints := range node.TableHints {
+			if hints.HintName.L == HintIgnorePlanCache {
+				checker.cacheable = false
+				checker.reason = "ignore plan cache by hint"
+				return in, true
+			}
+		}
 	case *ast.VariableExpr, *ast.ExistsSubqueryExpr, *ast.SubqueryExpr:
 		checker.cacheable = false
 		checker.reason = "query has sub-queries is un-cacheable"
diff --git a/planner/core/plan_cacheable_checker_test.go b/planner/core/plan_cacheable_checker_test.go
index 658537bde4188..e87a08592eb16 100644
--- a/planner/core/plan_cacheable_checker_test.go
+++ b/planner/core/plan_cacheable_checker_test.go
@@ -53,7 +53,9 @@ func TestCacheable(t *testing.T) {
 
 	tableRefsClause := &ast.TableRefsClause{TableRefs: &ast.Join{Left: &ast.TableSource{Source: tbl}}}
 	// test InsertStmt
-	stmt = &ast.InsertStmt{Table: tableRefsClause}
+	stmt = &ast.InsertStmt{Table: tableRefsClause} // insert-values-stmt
+	require.False(t, core.Cacheable(stmt, is))
+	stmt = &ast.InsertStmt{Table: tableRefsClause, Select: &ast.SelectStmt{}} // insert-select-stmt
 	require.True(t, core.Cacheable(stmt, is))
 
 	// test DeleteStmt
diff --git a/sessiontxn/txn_rc_tso_optimize_test.go b/sessiontxn/txn_rc_tso_optimize_test.go
index f321d40340496..3e945778ca107 100644
--- a/sessiontxn/txn_rc_tso_optimize_test.go
+++ b/sessiontxn/txn_rc_tso_optimize_test.go
@@ -105,7 +105,7 @@ func TestRcTSOCmdCountForPrepareExecuteNormal(t *testing.T) {
 		tk.MustExec("commit")
 	}
 	countTsoRequest, countTsoUseConstant, countWaitTsoOracle := getAllTsoCounter(sctx)
-	require.Equal(t, uint64(398), countTsoRequest.(uint64))
+	require.Equal(t, uint64(496), countTsoRequest.(uint64))
 	require.Equal(t, uint64(594), countTsoUseConstant.(uint64))
 	require.Equal(t, uint64(198), countWaitTsoOracle.(uint64))
 
@@ -137,7 +137,7 @@ func TestRcTSOCmdCountForPrepareExecuteNormal(t *testing.T) {
 		tk.MustExec("commit")
 	}
 	count := sctx.Value(sessiontxn.TsoRequestCount)
-	require.Equal(t, uint64(594), count)
+	require.Equal(t, uint64(693), count)
 }
 
 func TestRcTSOCmdCountForPrepareExecuteExtra(t *testing.T) {
@@ -234,7 +234,7 @@ func TestRcTSOCmdCountForPrepareExecuteExtra(t *testing.T) {
 		tk.MustExec("commit")
 	}
 	countTsoRequest, countTsoUseConstant, countWaitTsoOracle = getAllTsoCounter(sctx)
-	require.Equal(t, uint64(16), countTsoRequest.(uint64))
+	require.Equal(t, uint64(20), countTsoRequest.(uint64))
 	require.Equal(t, uint64(5), countTsoUseConstant.(uint64))
 	require.Equal(t, uint64(5), countWaitTsoOracle.(uint64))
 
@@ -412,7 +412,7 @@ func TestRcTSOCmdCountForPrepareExecuteExtra(t *testing.T) {
 	require.Nil(t, stmt)
 	tk.MustExec("commit")
 	countTsoRequest, countTsoUseConstant, countWaitTsoOracle = getAllTsoCounter(sctx)
-	require.Equal(t, uint64(3), countTsoRequest.(uint64))
+	require.Equal(t, uint64(4), countTsoRequest.(uint64))
 	require.Equal(t, uint64(2), countTsoUseConstant.(uint64))
 	require.Equal(t, 0, countWaitTsoOracle.(int))
 	tk.MustQuery("SELECT * FROM t1 WHERE id1 = 1").Check(testkit.Rows("1 1 1"))