diff --git a/.changeset/fair-lobsters-sin.md b/.changeset/fair-lobsters-sin.md
new file mode 100644
index 00000000000..2612e0e407d
--- /dev/null
+++ b/.changeset/fair-lobsters-sin.md
@@ -0,0 +1,5 @@
+---
+"@primer/react": patch
+---
+
+Add `isolation:isolate` to `ButtonGroup` container
diff --git a/src/ButtonGroup.tsx b/src/ButtonGroup.tsx
index 569c7af1137..c2f85c5d5b9 100644
--- a/src/ButtonGroup.tsx
+++ b/src/ButtonGroup.tsx
@@ -6,6 +6,7 @@ import {ComponentProps} from './utils/types'
 const ButtonGroup = styled.div`
   display: inline-flex;
   vertical-align: middle;
+  isolation: isolate;
 
   && > * {
     position: relative;
diff --git a/src/__tests__/deprecated/__snapshots__/Button.test.tsx.snap b/src/__tests__/deprecated/__snapshots__/Button.test.tsx.snap
index 1900cc1727b..a89ee5222b1 100644
--- a/src/__tests__/deprecated/__snapshots__/Button.test.tsx.snap
+++ b/src/__tests__/deprecated/__snapshots__/Button.test.tsx.snap
@@ -301,6 +301,7 @@ exports[`ButtonGroup renders consistently 1`] = `
   display: -ms-inline-flexbox;
   display: inline-flex;
   vertical-align: middle;
+  isolation: isolate;
 }
 
 .c0.c0 > * {