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RxStudio 2021-11-25

Initial release.

Affected simulation endpoints:

  • phenytoin_bay_ncmin

RxStudio 2021-10-15

Initial release.

Affected simulation endpoints:

  • voriconazole_bay_cmin_mic_ratio
  • voriconazole_bay_fauc_mic_ratio
  • voriconazole_cfr_cmin_mic_ratio
  • voriconazole_cfr_fauc_mic_ratio
  • voriconazole_emp_cmin_mic_ratio
  • voriconazole_emp_fauc_mic_ratio
  • voriconazole_pta_cmin_mic_ratio
  • voriconazole_pta_fauc_mic_ratio

RxStudio 2021-09-23

Initial release.

Affected simulation endpoints:

  • phenytoin_loading_ncmin_24h
  • phenytoin_optloading_ncmin_24h

RxStudio 2021-08-25

Fix doses in comparative plots.

Affected simulation endpoints:

  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic

RxStudio 2021-07-28

Initial release.

Affected simulation endpoints:

  • meropenem_emp_ftime_above_mic

RxStudio 2021-06-30

Initial release.

Affected simulation endpoints:

  • amikacin_bay_cmax_mic_ratio
  • amikacin_cfr_cmax_mic_ratio
  • amikacin_pta_cmax_mic_ratio

RxStudio 2021-06-04

Initial release.

Affected simulation endpoints:

  • ceftriaxone_bay_fauc_mic_ratio
  • ceftriaxone_bay_fcmin
  • ceftriaxone_bay_fcmin_mic_ratio
  • ceftriaxone_bay_ftime_above_mic
  • ceftriaxone_cfr_fauc_mic_ratio
  • ceftriaxone_cfr_fcmin
  • ceftriaxone_cfr_fcmin_mic_ratio
  • ceftriaxone_cfr_ftime_above_mic
  • ceftriaxone_emp_fauc_mic_ratio
  • ceftriaxone_emp_fcmin
  • ceftriaxone_emp_fcmin_mic_ratio
  • ceftriaxone_emp_ftime_above_mic
  • ceftriaxone_pta_fauc_mic_ratio
  • ceftriaxone_pta_fcmin
  • ceftriaxone_pta_fcmin_mic_ratio
  • ceftriaxone_pta_ftime_above_mic

RxStudio 2021-05-18

Add sparklines to visualize the individual patient PK parameters on the population distribution.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio

RxStudio 2021-05-14

Update Goti et al. (2018) model to use the actual covariance matrix instead of relying on standard deviations estimated from the published bootstrap confidence intervals.

Affected simulation endpoints:

  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2021-05-02

Add population model to the simulated blood concentration plot. Visualize up to the next 5 recommended doses until steady-state reached. Compute and visualize the predicted target PK/PD values until steady-state reached.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio

RxStudio 2021-04-09

Show results with warning for unreliable models instead of error.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio

RxStudio 2021-04-05

Update user interface with new input field making it possible to add further PK/PD models.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_cfr_ftime_above_mic
  • cefepime_cfr_ftime_above_mic
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin
  • cefepime_emp_fcmin
  • cefepime_emp_fcmin
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic
  • cefepime_pta_ftime_above_mic
  • cefepime_pta_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • gentamicin_pta_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_cfr_ftime_above_mic
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_emp_fcmin
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic
  • meropenem_pta_ftime_above_mic
  • meropenem_pta_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic
  • piperacillin-tazobactam_pta_ftime_above_mic
  • piperacillin-tazobactam_pta_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio
  • tobramycin_pta_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio
  • vancomycin_pta_cmin_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2021-03-17

Add support for custom timezones.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio

RxStudio 2021-03-16

Add exact timestamps to plots besides relative time from first dose. Show the exact timing of the next suggested dose and estimated time to reach steady-state. Fix order of PK/PD metrics in PDF reports.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2021-02-26

Update all simulation results to interactive plots with more details shown.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2021-02-08

Full localization of report, including better support for different units of measurements and the translation of all plot text element.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2021-02-01

Optional calculation of the probability of nephrotoxicity.

Affected simulation endpoints:

  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin

RxStudio 2021-01-18

Add PK parameters table.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_fcmin_mic_ratio
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_bay_ftime_above_mic
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_cfr_ftime_above_mic
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin
  • cefepime_emp_fcmin
  • cefepime_emp_fcmin
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_emp_fcmin
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_bay_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_bay_cmin_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_auc_mic_ratio
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_emp_cmin
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2020-12-08

Initial release.

Affected simulation endpoints:

  • piperacillin-tazobactam_bay_fauc_mic_ratio
  • piperacillin-tazobactam_bay_fcmin
  • piperacillin-tazobactam_bay_fcmin_mic_ratio
  • piperacillin-tazobactam_bay_ftime_above_mic
  • piperacillin-tazobactam_cfr_fauc_mic_ratio
  • piperacillin-tazobactam_cfr_fcmin
  • piperacillin-tazobactam_cfr_fcmin_mic_ratio
  • piperacillin-tazobactam_cfr_ftime_above_mic
  • piperacillin-tazobactam_emp_fauc_mic_ratio
  • piperacillin-tazobactam_emp_fcmin
  • piperacillin-tazobactam_emp_fcmin_mic_ratio
  • piperacillin-tazobactam_emp_ftime_above_mic
  • piperacillin-tazobactam_pta_fauc_mic_ratio
  • piperacillin-tazobactam_pta_fcmin
  • piperacillin-tazobactam_pta_fcmin_mic_ratio
  • piperacillin-tazobactam_pta_ftime_above_mic

RxStudio 2020-11-18

Initial release.

Affected simulation endpoints:

  • meropenem_bay_fauc_mic_ratio
  • meropenem_bay_fcmin
  • meropenem_bay_fcmin_mic_ratio
  • meropenem_bay_ftime_above_mic
  • meropenem_cfr_fauc_mic_ratio
  • meropenem_cfr_fcmin
  • meropenem_cfr_fcmin_mic_ratio
  • meropenem_cfr_ftime_above_mic
  • meropenem_emp_fauc_mic_ratio
  • meropenem_emp_fcmin
  • meropenem_pta_fauc_mic_ratio
  • meropenem_pta_fcmin
  • meropenem_pta_fcmin_mic_ratio
  • meropenem_pta_ftime_above_mic

RxStudio 2020-11-09

Initial release.

Affected simulation endpoints:

  • amikacin_bay_auc_mic_ratio
  • amikacin_bay_cmin_mic_ratio
  • gentamicin_bay_auc_mic_ratio
  • gentamicin_bay_cmin_mic_ratio
  • tobramycin_bay_auc_mic_ratio
  • tobramycin_bay_cmin_mic_ratio

RxStudio 2020-11-07

Initial release.

Affected simulation endpoints:

  • amikacin_cfr_auc_mic_ratio
  • amikacin_cfr_cmin_mic_ratio
  • gentamicin_cfr_auc_mic_ratio
  • gentamicin_cfr_cmin_mic_ratio
  • tobramycin_cfr_auc_mic_ratio
  • tobramycin_cfr_cmin_mic_ratio

RxStudio 2020-11-05

Initial release.

Affected simulation endpoints:

  • amikacin_emp_auc_mic_ratio
  • amikacin_emp_cmin
  • amikacin_emp_cmin_cmax
  • amikacin_emp_cmin_mic_ratio
  • amikacin_pta_auc_mic_ratio
  • amikacin_pta_cmin
  • amikacin_pta_cmin_cmax
  • amikacin_pta_cmin_mic_ratio
  • gentamicin_emp_auc_mic_ratio
  • gentamicin_emp_cmin
  • gentamicin_emp_cmin_cmax
  • gentamicin_emp_cmin_mic_ratio
  • gentamicin_pta_auc_mic_ratio
  • gentamicin_pta_cmin
  • gentamicin_pta_cmin_cmax
  • gentamicin_pta_cmin_mic_ratio
  • tobramycin_emp_auc_mic_ratio
  • tobramycin_emp_cmin
  • tobramycin_emp_cmin_cmax
  • tobramycin_emp_cmin_mic_ratio
  • tobramycin_pta_auc_mic_ratio
  • tobramycin_pta_cmin
  • tobramycin_pta_cmin_cmax
  • tobramycin_pta_cmin_mic_ratio

RxStudio 2020-10-14

Initial release.

Affected simulation endpoints:

  • vancomycin_bay_auc_mic_ratio
  • vancomycin_bay_cmin_mic_ratio

RxStudio 2020-10-10

Initial release.

Affected simulation endpoints:

  • cefepime_bay_ftime_above_mic

RxStudio 2020-10-06

Initial release.

Affected simulation endpoints:

  • cefepime_bay_fcmin_mic_ratio

RxStudio 2020-09-18

Initial release.

Affected simulation endpoints:

  • cefepime_emp_fauc_mic_ratio
  • cefepime_emp_fcmin

RxStudio 2020-09-17

Initial release.

Affected simulation endpoints:

  • vancomycin_cfr_auc_mic_ratio
  • vancomycin_cfr_cmin_mic_ratio
  • vancomycin_pta_auc_mic_ratio
  • vancomycin_pta_cmin_mic_ratio

RxStudio 2020-09-15

Initial release.

Affected simulation endpoints:

  • vancomycin_emp_cmin

RxStudio 2020-09-13

Initial release.

Affected simulation endpoints:

  • vancomycin_emp_auc_mic_ratio

RxStudio 2020-09-07

Enable multiple dosing regimens.

Affected simulation endpoints:

  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic

RxStudio 2020-09-05

Initial release.

Affected simulation endpoints:

  • cefepime_cfr_fcmin_mic_ratio
  • cefepime_cfr_ftime_above_mic
  • cefepime_pta_fcmin_mic_ratio
  • cefepime_pta_ftime_above_mic