diff --git a/setup.cfg b/setup.cfg
index f78ef4b5..d94b452f 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -17,7 +17,7 @@ packages = find:
 python_requires = >=3.6
 setup_requires = setuptools_scm
 install_requires =
-    astropy>=4,<4.3
+    astropy>=4
     networkx
     numpy
     scipy
@@ -31,14 +31,14 @@ console_scripts =
 test =
     pytest-astropy
     pytest-rerunfailures
-    speclite>=0.11
+    speclite>=0.14
 all =
     h5py
-    speclite>=0.11
+    speclite>=0.14
 docs =
     sphinx-astropy
     matplotlib
-    speclite>=0.11
+    speclite>=0.14
 
 [options.package_data]
 skypy = data/*,data/*/*,*/tests/data/*
diff --git a/tox.ini b/tox.ini
index a261a8fa..3f28e44a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -3,7 +3,7 @@ envlist =
     py{36,37,38,39}-test{,-all}{,-dev,-latest,-oldest}{,-cov}
     py{36,37,38,39}-test-numpy{116,117,118,119,120,121}
     py{36,37,38,39}-test-scipy{12,13,14,15,16,17}
-    py{36,37,38,39}-test-astropy{40,41,42}
+    py{36,37,38,39}-test-astropy{40,41,42,43}
     build_docs
     linkcheck
     codestyle
@@ -53,6 +53,7 @@ description =
     astropy40: with astropy 4.0.*
     astropy41: with astropy 4.1.*
     astropy42: with astropy 4.2.*
+    astropy43: with astropy 4.3.*
 
 # The following provides some specific pinnings for key packages
 deps =
@@ -74,12 +75,13 @@ deps =
     astropy40: astropy==4.0.*
     astropy41: astropy==4.1.*
     astropy42: astropy==4.2.*
+    astropy43: astropy==4.3.*
 
     dev: :NIGHTLY:numpy
     dev: :NIGHTLY:scipy
     dev: git+https://github.com/astropy/astropy.git#egg=astropy
 
-    latest: astropy==4.2.*
+    latest: astropy==4.3.*
     latest: numpy==1.21.*
     latest: scipy==1.7.*