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DESCRIPTION
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DESCRIPTION
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Package: ClustIRR
Type: Package
Title: Clustering of immune receptor repertoires
Version: 1.5.9
Authors@R: c(
person("Simo", "Kitanovski", email = "simokitanovski@gmail.com",
role = c("aut", "cre"), comment=c(ORCID="0000-0003-2909-5376")),
person("Kai", "Wollek", email = "kai.wollek@uni-duisburg-essen.de",
role = c("aut"), comment=c(ORCID="0009-0008-5941-9160")))
Description: ClustIRR analyzes repertoires of B- and T-cell receptors. It
starts by identifying communities of immune receptors with similar
specificities, based on the sequences of their complementarity-determining
regions (CDRs). Next, it employs a Bayesian probabilistic models to
quantify differential community occupancy (DCO) between repertoires,
allowing the identification of expanding or contracting communities
in response to e.g. infection or cancer treatment.
License: GPL-3 + file LICENSE
LazyData: false
Depends:
R (>= 4.4.0)
Imports:
blaster,
future,
future.apply,
grDevices,
igraph,
methods,
pwalign,
Rcpp (>= 0.12.0),
RcppParallel (>= 5.0.1),
reshape2,
rstan (>= 2.18.1),
rstantools (>= 2.4.0),
stats,
stringdist,
utils,
posterior,
visNetwork
Suggests:
BiocStyle,
knitr,
testthat,
ggplot2,
ggrepel,
patchwork
Encoding: UTF-8
NeedsCompilation: no
biocViews: Clustering, ImmunoOncology, SingleCell, Software, Classification
RoxygenNote: 7.2.3
VignetteBuilder: knitr
URL: https://github.com/snaketron/ClustIRR
BugReports: https://github.com/snaketron/ClustIRR/issues
Biarch: true
LinkingTo:
BH (>= 1.66.0),
Rcpp (>= 0.12.0),
RcppEigen (>= 0.3.3.3.0),
RcppParallel (>= 5.0.1),
rstan (>= 2.18.1),
StanHeaders (>= 2.18.0)
SystemRequirements: GNU make