diff --git a/dockers/docker-fpm-frr/isolate.j2 b/dockers/docker-fpm-frr/isolate.j2
index cfcd023ea1f3..9d19f9f40905 100755
--- a/dockers/docker-fpm-frr/isolate.j2
+++ b/dockers/docker-fpm-frr/isolate.j2
@@ -10,7 +10,13 @@ exit $?
 configure terminal
   router bgp {{ DEVICE_METADATA['localhost']['bgp_asn'] }}
 {% for neighbor_addr in BGP_NEIGHBOR %}
+{% if neighbor_addr | ipv4 %}
     neighbor {{ neighbor_addr }} route-map ISOLATE out
+{% else %}
+  address-family ipv6
+    neighbor {{ neighbor_addr }} route-map ISOLATE out
+  exit-address-family
+{% endif %}
 {% endfor %}
   exit
 exit
diff --git a/dockers/docker-fpm-frr/unisolate.j2 b/dockers/docker-fpm-frr/unisolate.j2
index 2a0780745d75..abd6a912c0d5 100755
--- a/dockers/docker-fpm-frr/unisolate.j2
+++ b/dockers/docker-fpm-frr/unisolate.j2
@@ -10,7 +10,13 @@ exit $?
 configure terminal
   router bgp {{ DEVICE_METADATA['localhost']['bgp_asn'] }}
 {% for neighbor_ip in BGP_NEIGHBOR %}
+{% if neighbor_ip | ipv4 %}
     no neighbor {{ neighbor_ip }} route-map ISOLATE out
+{% else %}
+  address-family ipv6
+    no neighbor {{ neighbor_ip }} route-map ISOLATE out
+  exit-address-family
+{% endif %}
 {% endfor %}
   exit
 exit
diff --git a/dockers/docker-fpm-quagga/isolate.j2 b/dockers/docker-fpm-quagga/isolate.j2
index cfcd023ea1f3..9d19f9f40905 100755
--- a/dockers/docker-fpm-quagga/isolate.j2
+++ b/dockers/docker-fpm-quagga/isolate.j2
@@ -10,7 +10,13 @@ exit $?
 configure terminal
   router bgp {{ DEVICE_METADATA['localhost']['bgp_asn'] }}
 {% for neighbor_addr in BGP_NEIGHBOR %}
+{% if neighbor_addr | ipv4 %}
     neighbor {{ neighbor_addr }} route-map ISOLATE out
+{% else %}
+  address-family ipv6
+    neighbor {{ neighbor_addr }} route-map ISOLATE out
+  exit-address-family
+{% endif %}
 {% endfor %}
   exit
 exit
diff --git a/dockers/docker-fpm-quagga/unisolate.j2 b/dockers/docker-fpm-quagga/unisolate.j2
index 2a0780745d75..abd6a912c0d5 100755
--- a/dockers/docker-fpm-quagga/unisolate.j2
+++ b/dockers/docker-fpm-quagga/unisolate.j2
@@ -10,7 +10,13 @@ exit $?
 configure terminal
   router bgp {{ DEVICE_METADATA['localhost']['bgp_asn'] }}
 {% for neighbor_ip in BGP_NEIGHBOR %}
+{% if neighbor_ip | ipv4 %}
     no neighbor {{ neighbor_ip }} route-map ISOLATE out
+{% else %}
+  address-family ipv6
+    no neighbor {{ neighbor_ip }} route-map ISOLATE out
+  exit-address-family
+{% endif %}
 {% endfor %}
   exit
 exit