diff --git a/pysynphot/locations.py b/pysynphot/locations.py
index 84e5d07..cadabe9 100644
--- a/pysynphot/locations.py
+++ b/pysynphot/locations.py
@@ -28,8 +28,7 @@
   directory shortcuts to actual paths.
 
 """
-from __future__ import division, print_function
-from six.moves.urllib import request
+from urllib import request
 
 import fnmatch
 import glob
diff --git a/pysynphot/test/test_ticket163.py b/pysynphot/test/test_ticket163.py
index 226c838..8c36716 100644
--- a/pysynphot/test/test_ticket163.py
+++ b/pysynphot/test/test_ticket163.py
@@ -1,6 +1,3 @@
-from __future__ import absolute_import, division, print_function
-from six import iteritems
-
 import os
 
 import pytest
@@ -33,7 +30,7 @@ def test_header(self):
         assert 'G15.7' == self.h1['tdisp1'].strip().upper()
 
     def test_keys(self):
-        for k, v in iteritems(self.keys):
+        for k, v in self.keys.items():
             assert self.h0[k] == v[0]
 
 
diff --git a/setup.py b/setup.py
index f39d0f7..ecabb33 100755
--- a/setup.py
+++ b/setup.py
@@ -26,7 +26,6 @@
         'astropy',
         'numpy<2',
         'beautifulsoup4',
-        'six'
     ],
     tests_require=['pytest', 'pytest-remotedata'],
     packages=['pysynphot',