diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 4820b5e..f1fb069 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -10,6 +10,10 @@ on:
   pull_request:
   create:
 
+env:
+  PKG_HOMEBREW_DEPS: >-
+    libxml2
+
 jobs:
   notify:
     runs-on: ubuntu-latest
@@ -53,7 +57,7 @@ jobs:
     runs-on: ${{ matrix.os }}
     strategy:
       matrix:
-        os: [windows-latest, ubuntu-latest]
+        os: [macos-latest, windows-latest, ubuntu-latest]
         perl: ['5']
         include:
           - { os: 'ubuntu-latest', perl: "5.32" }
@@ -71,6 +75,13 @@ jobs:
         with:
           name: dist
 
+      # Setup system package deps
+      - name: Setup system deps (homebrew)
+        if: runner.os == 'macOS'
+        run: |
+          brew install ${{ env.PKG_HOMEBREW_DEPS }}
+          echo "PKG_CONFIG_PATH=/usr/local/opt/libxml2/lib/pkgconfig" >> $GITHUB_ENV
+
       - name: Set up perl
         uses: shogo82148/actions-setup-perl@v1
         if: matrix.os != 'windows-latest'