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MICCAI2024-UNest

This is the official repo for our MICCAI 2024 paper: "Structural Attention: Rethinking Transformer for Unpaired Medical Image Synthesis".

Setting Docker environment

Create a Docker image based on the Dockerfile available in this repository using docker build -t unest:latest . After that you can run:

docker run --name unest --gpus all --shm-size=16g -it -v /path/to/data/root:/data unest:latest

Installation

  • pip install -r requirements.txt
  • Download SAM ckpt: wget https://dl.fbaipublicfiles.com/segment_anything/sam_vit_h_4b8939.pth

Data preparation

Download MR-PET-CT MRXFDG dataset. Run the code preprocessing_images.py to process images in the proper format for UNest and getting the masks.

Train UNest

Here are the sampled command to train UNest for MR to CT translation.

python train.py --dataroot ../../data/ --gpu_ids 0 --display_id 0 --model structured_trans \ 
--name base_model --dataset_mode unaligned_mask depth 4 --structured_shape_iter 0 \
--lambda_seg 1 --fth 0.75 --out_kernel 7 --load_size 200 --pad_size 224 --preprocess \ 
resize_pad --netG unest --vit_img_size 224 224 --window_size 2 --batch_size 32 \ 
--n_epochs 50 --n_epochs_decay 50 --display_freq 5000 --print_freq 1000 --save_epoch_freq 5 \
--save_latest_freq 500 --no_flip --Aclass A --Bclass B --include_mask_val --n_layers_D 3

Notable arguments include:

  • structured_shape_iter: Directly use ground-truth segmentation instead of the predicted segmentation in the first few iterations.
  • lambda_seg: weights of segmentation loss
  • fth: threshold to determine whether a pixel is foreground or background
  • out_kernel: the final kernel of the decoder to regress each pixel
  • vit_img_size: match the image resolution # Only modify when changing iamge resolution
  • upsample: what convolution techniques used to upsampling the image features in the decoder
  • window_size: window size for local attention # Divisible by the height/width of images

Related Projects

cyclegan-pix2pix | ViT-V-Net | Recursive-Cascade-Networks

Please check out our concurrent work on unpaired medical image synthesis: MaskGAN

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