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O-LM interneuron model (Lawrence et al. 2006)
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<html><pre> This is the readme for the model associated with the paper: Lawrence JJ, Saraga F, Churchill JF, Statland JM, Travis KE, Skinner FK, McBain CJ (2006) Somatodendritic Kv7-KCNQ-M channels control interspike interval in hippocampal interneurons. J Neurosci 26:12325-38 Usage: Auto-launch from ModelDB or download and extract the archive and then under ms-win ------ Compile the mod files by running mknrndll and changing to the extracted folder and selecting to create the nrnmech.dll. Then double click on the mosinit.hoc file linux/unix ---------- Compile the mod files by running nrnivmodl in the extracted folder. Then run "nrngui mosinit.hoc" mac os x -------- Drag and drop the extracted folder onto the mknrndll icon. Drag and drop the mosinit.hoc file from the extracted folder onto the nrngui icon. ---------- Once the simulation starts you can create subplots of Fig 9 by clicking the appropriately labeled buttons or you can create the whole figure by clicking the create all of fig 9 button (lower right in control box) and you will get a figure like: <img src="./screenshot.jpg" alt="screenshot"> Note: The variable step method was used in this demo, if you would like to run the simulation as in the publication you can run cvode_active(0). The model files were supplied by Dr Saraga.
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