Model snapshot and evaluation plan version 1.3

This release contains:

• the PK-Sim snapshot (*.json) file of the PBPK model (what is a "PK-Sim snapshot")
• static content (e.g. text blocks, *.md files) as inputs for an evaluation plan
• the evaluation plan (evaluation-plan.json) to create an evaluation report using the snapshot and static text blocks to display the performance of the model

The latest release of the PK-Sim project model file and the respective evaluation report can be found here.

Downloads

Dapagliflozin PK-Sim snapshot file

Fixed issues and Improvements

• Bugfixe in the report (observed data path in the comparison plots)

Model snapshot and evaluation plan version 1.2

This release contains:

• the PK-Sim snapshot (*.json) file of the PBPK model (what is a "PK-Sim snapshot")
• static content (e.g. text blocks, *.md files) as inputs for an evaluation plan
• the evaluation plan (evaluation-plan.json) to create an evaluation report using the snapshot and static text blocks to display the performance of the model

The latest release of the PK-Sim project model file and the respective evaluation report can be found here.

Downloads

Dapagliflozin PK-Sim snapshot file

Fixed issues and Improvements

• Minor bugfixes in the report (typos, broken links)

Model snapshot and evaluation plan version 1.1

This release contains:

• the PK-Sim snapshot (*.json) file of the PBPK model
• static content (e.g. text blocks, *.md files) as inputs for an evaluation plan
• the evaluation plan (evaluation-plan.json) to create an evaluation report using the snapshot and static text blocks to display the performance of the model

The latest release of the PK-Sim project model file and the respective evaluation report can be found here.

Downloads

Dapagliflozin PK-Sim snapshot file

Model and report version 1.0

Description

Dapagliflozin whole-body PBPK model and report on model building, model features and model evaluation.
Attached PK-Sim project files built under OSP software version 8.0.

Read online

Evaluation report Dapagliflozin PBPK model v1.0

Download PDF

Evaluation report Dapagliflozin PBPK model v1.0

Downloads

Dapagliflozin PK-Sim project file
Dapagliflozin PK-Sim snapshot file