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Update changelog for next version
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ctsa committed Apr 18, 2024
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14 changes: 14 additions & 0 deletions CHANGELOG.md
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# Change Log

## v0.11.0 - 2024-04-18

Improve a number of discovery and scoring features related to inversions, inverted breakpoints and large deletions.

### Changed
- CR-323 Improve scoring for a number of cases relevant to inversions and inverted breakpoints
- CR-321 Change contig flank size handling to improve large inversion calling
- CR-318 Expand trimmed read search region for large SV candidates
- Improves recall for inverted breakpoints and duplications
- CR-317 Standardize on csi indexing for bam output

### Fixed
- CR-324 Fix non-deterministic inversion output

## v0.10.0 - 2024-03-05

Initial github release
1 change: 1 addition & 0 deletions docs/user_guide.md
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Expand Up @@ -105,6 +105,7 @@ All phred-scaled quality scores in the VCF output have a maximum value of 999.

The following filters may be applied to each VCF record:

- `ConflictingBreakpointGT` - Genotypes of breakpoints in a multi-breakpoint event conflict in the majority of cases (This filter is only relevant to inversions at present)
- `MinQUAL` - The SV allele quality score (`QUAL`) is less than 10
- `MaxScoringDepth` - Read depth at the SV locus exceeds 1000x, so all scoring and genotyping steps were disabled.
- `InvBreakpoint` - This breakpoint is represented as part of a separate VCF inversion record (the inversion record shares the same EVENT ID)
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