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2.10.1

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@d-cameron d-cameron released this 20 Oct 01:47
· 313 commits to master since this release

Incremental release fixing some minor issues with with 2.10.0 release

  • #410 added locking on the setupreference step
    • prevents bwa index corruption due to concurrent writing from two GRIDSS instances using the same reference
  • virusbreakend-build.sh: creating sequence dictionaries so virusbreakend.sh never has to write to the virusbreakenddb directory
  • virusbreakend.sh: reusing GRIDSS metrics from the full BAM if they already exist
  • gridss_extract_overlapping_fragments.sh/virusbreakend.sh: sampling 10M reads when calculating metrics.
    • sampling only 1M reads was resulting in telomeric bias and underreporting of QUAL scores on 100x data
  • virusbreakend.sh: reduced heap size when running gridss.sh to 13g so it fits in a 4core/16gb VM