ProteoFAV v0.2.3: PROtein Feature Aggregation and Variants - Communications Biology Archival Release

ProteoFAV v0.2.3 represents a stable version of our Python module designed for cross-mapping protein structures and sequences, enriching protein structures with sequence features, annotations, and genetic variants. This release is specifically archived in connection with our publication, "A unified approach to evolutionary conservation and population constraint in protein domains highlights structural features and pathogenic sites," accepted by Communications Biology.

Please note: This version is archived for academic purposes, to facilitate replication of the results and methodologies presented in our publication. For users seeking to utilize ProteoFAV for new projects, we recommend using the most current version for access to the latest features and enhancements.

Key Features of v0.2.3:

• Cross-mapping protein structures and sequences with support for mmCIF, PDB, and other formats.
• Annotation of protein structures with sequence features and genetic variants.
• Comprehensive data handling with Pandas for efficient analysis and data merging.

Citation:

Refer to our paper for detailed methodology and findings: Stuart A. MacGowan, Fábio Madeira, Thiago Britto-Borges, and Geoffrey J. Barton, "A unified analysis of evolutionary and population constraint in protein domains highlights structural features and pathogenic sites." Pre-print available at https://doi.org/10.21203/rs.3.rs-3160340/v1.

License:

Released under the MIT license by Thiago Britto-Borges and contributors.

Feedback and contributions to ProteoFAV are welcomed to further refine and enhance the project.

tag/ProteoFAV_0.2.0_beta

Bumped the version.