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[ENH] Clarify shape of PDT2 images and recommend acq entity for split PDw/T2w images #1448

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merged 3 commits into from
Mar 24, 2023

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effigies
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@effigies effigies commented Mar 16, 2023

To briefly summarize the discussion in #223, PDT2 sequences are common in clinical settings, taking advantage of view-sharing processes to simultaneously acquire PDw and T2w volumes. It is currently ambiguous how these files should be named if the volumes are split into individual NIfTI files, which is the default behavior of BIDS converters such as dcm2niix.

It was initially proposed to add the echo- entity, which would be correct but unique among anatomical images. It was objected that clinical users may not easily recognize whether echo-1_PDT2 indicates the PDw or T2w image. On the other hand, it is possible to have PDw or T2w images in addition to PDT2 images, and recommendations for consistent unambiguous naming would be desirable.

This change intends to clarify that PDT2 images SHOULD be 4D with length 2. If PDT2 images are split, their suffixes SHOULD be PDw and T2w, respectively, and we suggest using the acq- parameter to indicate they come from the same source. @tiborauer suggested acq-partial; here I propose acq-PDT2 to be very explicit.


The expected impact of this is low, as PDT2 files are rare outside clinical contexts. None appear in OpenNeuro unless they have already been renamed according to the proposed convention.

The practical consequence for the validator are:

  1. Add a warning if PDT2 images do not have 2 volumes. This is done in schema, and I do not currently intend to backport it to the legacy validator.
  2. Remove support for PDT2map, a modality that is not believed to actually exist anywhere. This may need to be reverted and PDT2map re-added to the standard if it turns out that anybody is using it.

Closes #223.

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tiborauer commented Mar 16, 2023

Let me add a short elaboration. I suggested we do not have to treat these images any differently than other T2w and PDw images and use the acq field, as usual, to differentiate them. I suggested acq-partial only as an example and only if it their most relevant and distinctive feature (i.e., partial brain coverage), as suggested by @CPernet.
Similarly, I would not restrict or prescribe the value of acq field but only suggest them ("SHOULD") in line with its exiting use.

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codecov bot commented Mar 16, 2023

Codecov Report

Patch and project coverage have no change.

Comparison is base (8bc376e) 87.90% compared to head (a145d9e) 87.90%.

Additional details and impacted files
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@effigies
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Thanks Tibor. I agree. If there is a wording improvement to make that clearer, please feel free to suggest it.

(for example, [Johnson et al. 1994](https://pubmed.ncbi.nlm.nih.gov/8010268/)).
If separated into 3D volumes, the `PDw` and `T2w` suffixes SHOULD be used
instead, and an acquisition entity MAY be used to indicate the origin of the
images, for example, `acq-PDT2_PDw.nii` and `acq-PDT2_T2w.nii`.
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I suggest:
and an acquisition entity MAY be used to distinguish the images from others with the same modality. For example, if the PD/T2 images cover only part of the brain, then acq-partial_PDw.nii and acq-partial_T2w.nii. If the PD/T2 images differ from other PDw and T2w images only in the sequence, then acq-PDT2_PDw.nii and acq-PDT2_T2w.nii.

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Thanks @effigies for creating this PR, and for updating it as per my comments in #223. I've reviewed it carefully and it looks good to me.

@effigies effigies requested review from tiborauer, CPernet and agahkarakuzu and removed request for erdalkaraca and tsalo March 20, 2023 16:59
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Thank you @effigies for sending out this PR and @tiborauer @nicholst @CPernet for clarifying the use cases of this application, which were not completely resolved during the merging of BEP001.

This PR looks good to me and I think it adds to the clarity of the differentiation between weighted and quantitative use cases.

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Thanks for the reviews, all!

@effigies effigies merged commit 19d6b65 into bids-standard:master Mar 24, 2023
@effigies effigies deleted the enh/clarify_pdt2 branch March 24, 2023 11:56
@sappelhoff sappelhoff changed the title ENH: Clarify shape of PDT2 images and recommend acq entity for split PDw/T2w images [ENH] Clarify shape of PDT2 images and recommend acq entity for split PDw/T2w images Nov 13, 2023
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PDT2 anatomical modality: Recommendations and potential use of _echo
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