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Nomenclature and definitions of protein complexes in BEL

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bio2bel/complexportal

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Bio2BEL Complex Portal

Download data from ftp://ftp.ebi.ac.uk/pub/databases/intact/complex/current/complextab/homo_sapiens.tsv

The first line contains the header of:

  • Complex ac
  • Recommended name
  • Aliases for complex
  • Taxonomy identifier
  • Identifiers (and stoichiometry) of molecules in complex
  • Confidence
  • Experimental evidence
  • Go Annotations
  • Cross references
  • Description
  • Complex properties
  • Complex assembly
  • Ligand
  • Disease
  • Agonist
  • Antagonist
  • Comment
  • Source

Goal 1: Generate BEL namespace file using bel_resources.write_namespace.

Arguments to this function:

  • values should be a dictionary from keys as entries from Complex ac and the values as 'C', which represents complexes in BEL namespace files
  • namespace_name should be 'Complex Portal'
  • namespace_keyword should be 'complexportal'.

Goal 2: Create an instance of pybel.BELGraph and populate it with links from complexes to their constituent entities (in Identifiers (and stoichiometry) of molecules in complex) using pybel.BELGraph.add_part_of.

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